A5100354373- Congenital Heart Disease Studies
- Tracheal and airway disorders
- Coronary Artery Anomalies
- Congenital Diaphragmatic Hernia Studies
- Dialysis and Renal Disease Management
- Pulmonary Hypertension Research and Treatments
- Vascular anomalies and interventions
- Chronic Kidney Disease and Diabetes
- Cardiac Structural Anomalies and Repair
- Heart Failure Treatment and Management
- Vascular Anomalies and Treatments
- Cardiovascular Disease and Adiposity
- Esophageal and GI Pathology
- Cardiovascular Issues in Pregnancy
- Long-Term Effects of COVID-19
- Aortic Disease and Treatment Approaches
- Anesthesia and Neurotoxicity Research
- Cardiac Arrhythmias and Treatments
- Acute Kidney Injury Research
- Coronary Interventions and Diagnostics
- SARS-CoV-2 and COVID-19 Research
- Hepatitis B Virus Studies
- Renal Diseases and Glomerulopathies
- Cardiovascular and Diving-Related Complications
- Hepatocellular Carcinoma Treatment and Prognosis
China Medical University
2025
First Hospital of China Medical University
2020-2025
Nanjing University
2025
Nanjing General Hospital of Nanjing Military Command
2025
Guangzhou Medical University
2014-2024
Beijing University of Chinese Medicine
2015-2024
First Hospital of Jilin University
2016-2024
Jilin University
2016-2024
First Affiliated Hospital of Wenzhou Medical University
2017-2024
Wenzhou Medical University
2014-2024
Evidence highlights the importance of muscular strength as a protective factor for health and function across aging populations. The purpose this study was to examine extent which low normalized grip (NGS) serves biomarker both cardiometabolic disease physical disability in U.S. Chinese adults. Middle aged older adults from National Health Nutrition Examination Survey 2011–2012 2013–2014 combined surveys (n = 4,544), 2011 wave China Retirement Longitudinal Study 6,030) were included....
Abstract Skeletal disorders are commonly diagnosed by X-ray imaging, but the radiation limits its use. Optical imaging through near-infrared-II window (NIR-II, 1000–1700 nm) can penetrate deep tissues without risk, targeting of contrast agent is non-specific. Here, we report that lanthanide-doped nanocrystals passively target bone marrow, which be effective for over two months. We therefore develop high-resolution NIR-II method disease diagnosis, including 3D instrumentation to show...
ABSTRACT Candida haemulonii complex ( , var. vulnera and duobushaemulonii ) consists of emerging pathogens. Thirty-one isolates from 14 hospitals in China were studied for their species classification antifungal susceptibilities. Performances molecular (i.e., ribosomal DNA [rDNA] internal transcribed spacer [ITS] sequencing, D1/D2 ITS sequencer-based capillary gel electrophoresis [SCGE]) phenotypic identification methods compared. Twenty-six (83.9%) 31 identified as C. 5 by sequencing the...
Bats are reservoirs of many important viral pathogens. To evaluate whether bat-parasitic blood-sucking arthropods participate in the circulation these viruses, it is necessary to conduct unbiased virome studies on arthropods.
Transforming growth factor-beta1 (TGF-β1) is a major factor in pathogenesis of chronic hepatic injury. Carbon tetrachloride (CCl4) liver toxicant, and CCl4-induced injury mouse classical animal model chemical However, it still unclear whether TGF-β1 involved the process acute The present study aimed to evaluate role its signaling molecule Smad3 induce by CCl4. results showed that CCl4 induced mice effectively confirmed H&E staining tissues, levels not only markers serum ALT AST, but also...
Background: Accumulating evidence suggests that platelet-derived growth factor-BB (PDGF-BB) and vascular endothelial factor(VEGF) play a role in the progression of pulmonary arterial hypertension (PAH).Since chronic hypoxia is responsible for intimal hyperplasia disordered angiogenesis arteries, which are histological hallmarks PAH, we explored PDGF-BB/KLF4/VEGF signaling axis artery cells (PAECs). Methods: Adult male Wistar rats were used to study hypoxia-induced or monocrotaline...
Background. Xenogeneic organ transplantation has been proposed as a potential approach to fundamentally solve shortage problem. immune responses across species is one of the major obstacles for clinic application xeno-organ transplantation. The generation glycoprotein galactosyltransferase α 1, 3 ( GGTA1 ) knockout pigs greatly contributed reduction hyperacute xenograft rejection. However, severe rejection can still be induced by xenoimmune porcine histocompatibility complex antigens swine...
<p>Rheumatoid arthritis (RA) is a poly-articular systemic autoimmune disorder characterized by infiltration of immune cells, synovial hyperplasia and joint destruction. Macrophages (MΦs) can polarize into either pro-inflammatory M1 or anti-inflammatory M2 phenotype in response to different environmental signals. In RA, MΦs are prone the phenotype. Reprogramming has shown promise treating diseases, <i>e.g.</i>, chimeric antigen receptor-MΦ (CAR-M)-based adoptive...
To evaluate the potential benefits of Bacteroides fragilis 839 (BF839), a next-generation probiotics, in reducing myelosuppression and gastrointestinal toxicity associated with chemotherapy breast cancer patient.
Wound care treatment is a serious issue faced by the medical staffs due to its variety and complexity. dressings are typically used manage various types of wounds. In this study, polyurethane (PU) fibers containing mupirocin (Mu), commonly antibiotic in wound care, were fabricated via electrospinning technique. The aim study was develop biomedical electrospun fiber scaffolds for preventing infections with good compatibility demonstrate their applications as anti-infective burn dressings....
Purpose To investigate the dietary nutrient intake of Maintenance hemodialysis (MHD) patients, identify influencing factors, and explore correlation between nutritional disease control indicators.
Abstract Background Nutrition support is important for clinical management to improve outcomes of infants following congenital heart surgery. Protein‐enriched and energy‐enriched formula (PE‐formula) may help provide adequate nutrition promote wound healing. However, the effects tolerance increased protein energy intakes these have not been well defined. Objective To evaluate a PE‐formula compared with standard (S‐formula) in first 5 days after Methods : Fifty were randomly assigned...
Purpose: Berberine (BBR), an alkaloid produced by a traditional Chinese plant, was recently attributed multiple effects on lipometabolism, inflammation, and fibrosis. Thyroid-associated ophthalmopathy (TAO) is highly associated with these pathologic changes. Thus, we aimed to examine the potential therapeutic effect of BBR in vitro model TAO. Methods: Orbital fibroblasts (OFs) obtained from control donors (n = 6) or patients TAO were cultured. The CCK-8 assay conducted for assessing optimal...
Dysfunction and injury of endothelial cells play critical roles in pulmonary arterial hypertension, including aberrant proliferation, suppressed apoptosis, excessive angiogenesis. The 12-lipoxygenase 12-hydroxyeicosatetraenoic acid pathway, which has been considered as a crucial mediator, elevates vascular resistance pressure. However, the mechanisms underlying bioactivity vasculature, especially cells, are still elusive. Thus we aim to determine key role...
A capillary electrophoresis fingerprint was constructed for Sanhuang tablet, a Chinese traditional patent medicine, that commonly used in clinical practice, where the isosceles trapezoid method first applied optimization of background electrolyte solution, and resolution index performed to assess experimental conditions; furthermore, novel linear quantitative established accurate qualitative discrimination test samples from diverse commercial brands. The analysis coupled with determination...
Overlapping idiopathic membranous nephropathy (IMN) and immunoglobulin A (IgAN) is rare. This study aims to investigate the unique prognostic, clinical, renal histopathological characteristics of IMN+IgAN. retrospective observational included 73 consecutive cases IMN+IgAN 425 IMN treated between September 2006 November 2015. Prognostic baseline clinical data were compared two patient groups. Poor prognostic events a permanent 50% reduction in eGFR, end-stage disease, all-cause mortality....
Objectives: This study aimed to investigate the unique prognostic, clinical, and renal histopathological characteristics of patients with idiopathic membranous nephropathy (IMN) different levels proteinuria.Methods: retrospective observational included 190 IMN low proteinuria (low group), 193 medium (medium 123 high (high group) treated between September 2006 November 2015. Prognostic baseline clinical data were compared among three groups. Poor prognostic events occurrence a persistent 50%...
Abstract Background Hemodialysis patients require a reasonable dietary intake to manage their disease progression effectively. However, there is limited research on these patients’ overall knowledge, attitude, and practice (KAP) status. This study aimed investigate the KAP status latent profiles in hemodialysis identify sociodemographic disease-related factors associated with practice. Methods A multicenter cross-sectional involving 425 was conducted. questionnaire used evaluate of patients....