- Chemical synthesis and alkaloids
- Ocular Diseases and Behçet’s Syndrome
- Intraocular Surgery and Lenses
- Ocular Infections and Treatments
- Retinal Diseases and Treatments
- Acute Ischemic Stroke Management
- LGBTQ Health, Identity, and Policy
- Smoking Behavior and Cessation
- Substance Abuse Treatment and Outcomes
- Retinal and Macular Surgery
- Retinal and Optic Conditions
- Opioid Use Disorder Treatment
- Family Support in Illness
- Syphilis Diagnosis and Treatment
- Vasculitis and related conditions
- Attachment and Relationship Dynamics
- Poisoning and overdose treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Glaucoma and retinal disorders
- Vascular Malformations Diagnosis and Treatment
- Ocular Surface and Contact Lens
- Neonatal and Maternal Infections
- Treatment of Major Depression
- Cardiac Arrest and Resuscitation
- Cardiovascular Health and Risk Factors
Northwestern University
2025
Greenlane Clinical Centre
2017-2024
Auckland District Health Board
2013-2024
University of Southampton
2023
University of Auckland
2011-2021
Pfizer (United States)
2021
Comer Children's Hospital
2020
University of Oxford
1997-2017
North Tyneside General Hospital
2014
John Radcliffe Hospital
2013
<h3>Objective:</h3> To evaluate the 5-year impact of stroke and TIA on utility quality-adjusted survival. <h3>Methods:</h3> patients from a UK population-based study (Oxford Vascular Study) were recruited 2002 to 2007, followed up until 2012. Quality life was assessed over 5 years using EQ-5D (EuroQol-5 Dimensions), with responses converted into utilities ranging −0.59 (worse than death) 1 (perfect health), population valuations. Utilities for compared those in matched controls obtained 2006...
The overall effectiveness of nicotine replacement therapy could be greater if the were targeted at those most likely to respond.Variants dopamine D2 receptor (DRD2 32806 C/T) have been implicated in initiation and maintenance smoking, 1 2 these variants may also related response therapy. 3Additionally, mechanisms addiction differ men women. 4 With this evidence mind, we examined whether is modified by sex genotype.
To assess the feasibility of a randomized clinical trial supervised injectable versus oral methadone maintenance and to medium-term treatment outcomes.Randomized (MMT). Trial participants were dependent illicit opiate injectors allocated at intake or treatment.Specialist addictions centre in South London.Forty seeking treatment.Daily maintenance, delivered centre.Frequency heroin use frequency drug injecting during 30 days before prior 6-month follow-up.frequency methadone, crack cocaine,...
This study uses 2021 data on the percentage of unavailable opioid tests in US to examine how involvement informs injury death investigations.
Objectives: To describe the mental health of lesbians in New Zealand, and to document their accounts experience services. Method: This is a descriptive cross-sectional study. A postal questionnaire, Lesbian Mental Health Survey, was distributed via lesbian newsletters 1222 women throughout Zealand. measures included General Questionnaire (GHQ-28), Interview Schedule for Social Interaction (ISSI), respondents' histories sexual abuse psychiatric histories. Experiences services were sought....
Women patients suffer from a range of mental disorders similar to those that men may experience. However, there are some striking differences in the prevalence specific disorders, and their presentation management. Some illnesses only occur women. It seems women have different experience treatment, consequence needs also way health professionals perceive needs. These embedded wider cultural milieu which we live. There particular issues for relation to, example, childhood sexual abuse, rape...
Purpose: The aim of this study was to identify the factors associated with positive culture sample in patients endophthalmitis based on clinical presentation and multimodal intraocular sampling. Design: Retrospective review. Methods: A total 259 subjects a diagnosis presented tertiary ophthalmic referral center between 2006 2018. Patient demographics, presenting findings results aqueous vitreous sampling were analyzed. Results: Mean age 64.2 (± 22.6) years 52.9% female. Endophthalmitis...
Background: This study explores local trends in antimicrobial resistance and its influence on long-term visual outcomes following treatment with broad-spectrum empiric intravitreal antibiotics. Methods: All patients undergoing intraocular sampling for endophthalmitis from Auckland between January 2006–May 2023 were included. The impact of the final outcome was analysed using logistic regression models. Results: 389 cases included, 207 eyes (53.2%) culture positive. When tested, all...
To compare 1-year outcomes of eyes with diabetic macular edema (DME) treated in routine clinical practice based on the proportion visits where intravitreal VEGF inhibitor injections were delivered.
as smoking and exposure to secondhand smoke outside the home were more prevalent in New Zealand early 1980s.This may explain apparently stronger association between household mortality 1996-9 cohort compared with 1981-4 cohort.The results from this study add weight of evidence harm caused by passive support steps reduce other people's smoke-in settings.We thank Jackie Fawcett June Atkinson for technical help data extraction analysis.
To determine whether patients with TIA or ischemic stroke coexisting cardiovascular disease (i.e., history of coronary peripheral artery disease) are still at high risk recurrent events despite current secondary prevention guidelines.In a population-based study in Oxfordshire, UK (Oxford Vascular Study), we studied consecutive for 2002-2014. Patients were treated according to guidelines and determined risks events, stroke, major bleeding stratified by the presence disease.Among 2,555 (9,148...
Aims To examine the role of early vitrectomy in management endophthalmitis from all causes. Methods Retrospective study 290 consecutive subjects diagnosed with at Auckland District Health Board between 1 January 2006 and 31 July 2019. Main outcome measure was visual acuity 9-month follow-up proportion severe vision loss (≤20/200). Results Median age presentation 70.4 years 151 (52.1%) were women. Cataract surgery most common cause 92 (31.7%) followed by intravitreal injection 57 (19.7%),...
Abstract Background Epiretinal membrane (ERM) is a common finding in patients with uveitis that contributes to visual impairment. We describe the long‐term acuity (VA) and morphometric progression epiretinal (ERM). Methods Retrospective cohort study of uveitic ERM from tertiary centre database. Multivariate analysis risk factors for was calculated using marginal Cox regression model estimate hazard ratios (HR). Results Two hundred sixteen eyes (4%) total 5450 were identified have an ERM. The...
To discover whether the timing of intravitreal antibiotics, from time presentation to injection, affects visual outcomes patients with endophthalmitis all causes.A retrospective study consecutive managed at Auckland District Health Board between 1 January 2004 and July 2021. The main outcome measure was final acuity follow-up proportion subjects severe vision loss (≤6/60).Three hundred seventy-four eyes were included in study, a median age 69.7 years presentation; 192 (51.6%) female....
Smoking prevalence and changes during inpatient detoxification were examined among 135 admissions to an alcohol drug unit, of whom 83 (61.5%) re-interviewed one week later. Ninety-two per cent the initial sample currently smokers; 87% misusers, 97% misusers 100% drug/alcohol misusers. Smokers consumed a daily mean 27 cigarettes before admission. Those classified as heavy smokers (smoking 40 or more prior admission) decreased their smoking levels by average 10.5 detoxification. Light (1-19...
Choroidal neovascularization is an uncommon complication of macular surgery. The functional outcome poor despite various treatment options, including laser photocoagulation, photodynamic therapy, and a variety surgical procedures. We report case iatrogenic choroidal in 69-year-old woman at the site inadvertent retinal trauma 5 weeks after epiretinal membrane peel. Visual acuity was 6/15 time diagnosis. Four intravitreal bevacizumab injections were administered over period 6 months;...
Purpose To compare functional and anatomical outcomes, rates of culture positivity number procedures in eyes with endophthalmitis following phacoemulsification surgery, treated either primary vitrectomy intravitreal antibiotics or vitreous tap antibiotic injection (T&I).Methods Patients developing after surgery between 2007 2016 were identified, outcomes compared the two treatment groups.Results 19 patients underwent a 22 T&I. There was significant improvement visual acuity T&I (p=.003)...
Many patients treated for head and neck cancer require nutritional support, which is often delivered using a gastrostomy tube. It difficult to predict will retain their tube in the long term. This study aimed identify factors affect duration of retention.In this retrospective study, 151 consecutive from one centre were audited. All had mucosal tumour neck, underwent insertion between 2003 2007.There near-complete data sets 132 patients. The was retained survivors (n = 66) mean 21.3 months...