Benjamin Sui

ORCID: 0000-0003-1324-9940
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About
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Research Areas
  • Cancer Cells and Metastasis
  • Wnt/β-catenin signaling in development and cancer
  • Hippo pathway signaling and YAP/TAZ

University of California, Irvine
2022

Maintenance of undifferentiated, long-lived, and often quiescent stem cells in the basal compartment is important for homeostasis regeneration multiple epithelial tissues, but molecular mechanisms that coordinately control cell fate quiescence are elusive. Here, we report an epithelium-intrinsic requirement Zeb1, a core transcriptional inducer epithelial-to-mesenchymal transition, mammary ductal side branching regenerative capacity. Our findings uncover evolutionarily conserved role Zeb1...

10.1016/j.celrep.2021.110240 article EN cc-by-nc-nd Cell Reports 2022-01-01
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