A5075666358- Retinal Diseases and Treatments
- Retinal Development and Disorders
- Glaucoma and retinal disorders
- Nitric Oxide and Endothelin Effects
- Neuroscience and Neuropharmacology Research
- Receptor Mechanisms and Signaling
- Retinopathy of Prematurity Studies
- Neuropeptides and Animal Physiology
- Eicosanoids and Hypertension Pharmacology
- Cardiac Ischemia and Reperfusion
- Black Holes and Theoretical Physics
- Cosmology and Gravitation Theories
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Aquaculture Nutrition and Growth
- Ion channel regulation and function
- Connexins and lens biology
- Interconnection Networks and Systems
- Biochemical effects in animals
- Cardiac electrophysiology and arrhythmias
- Neuroinflammation and Neurodegeneration Mechanisms
- Advanced Glycation End Products research
- Renin-Angiotensin System Studies
- Neurological Disorders and Treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Context-Aware Activity Recognition Systems
Kitasato University
2014-2024
Teikyo University
2020-2024
The University of Tokyo
1997-2024
Tokyo Medical University
2023-2024
Kyushu Institute of Technology
2022-2024
Yamaguchi University
1998-2023
Cell Biotech (South Korea)
2023
Biocat
2023
Pharmac
2019-2022
National Sanyo Hospital
2016-2019
The physicochemical properties of the H(2)O molecules adsorbed on TiO(2) surfaces during UV light irradiation were fully investigated by near-infrared (NIR) absorption spectroscopy. It was found that desorb heating effect source. Since amount decreased, distribution hydrogen bonds within resulting in a decrease surface tension clusters. under to be one most important driving forces which clusters spread out thermodynamically, forming thin layers. partial elimination hydrocarbons from...
Using viral vectors as gene delivery vehicles for therapy necessitates their quality control. Here, we report on nanopore sensing nondestructively inspecting genomes inside the nanoscale cargoes at single-molecule level. ionic current measurements, motion-tracked adeno-associated virus (AAV) they translocated through a solid-state nanopore. Considering varying contributions of electrophoretic forces from negatively charged internal polynucleotides different lengths, nanocargoes carrying...
The heterotetrameric phosphodiesterase (PDE) 6 complex, made up of α, β and two γ subunits, regulates intracellular cGMP levels by hydrolyzing in response to light activation G protein coupled receptors cones rods, making it an essential component the visual phototransduction cascade [Zhang, X. Cote, R.H. (2005) signaling vertebrate retinal photoreceptor cells. Front. Biosci., 10, 1191–1204.]. Using a genetic positional candidate cloning strategy, we have identified missense mutations within...
Etudes de la duree vie ces electrodes utilisables comme anodes pour le degagement d'oxygene
Ocular pathologic angiogenesis is a causative factor for retinopathy of prematurity, diabetic retinopathy, and age-related macular degeneration. In the present study, we examined effects rapamycin everolimus, inhibitors mammalian target (mTOR), on retinal in mice with oxygen-induced (OIR), an animal model proliferative ischemic retinopathy. Mice were exposed to 80% oxygen from postnatal day (P) 7 P10, then brought into room air subcutaneously injected everolimus. The neovascular tufts, size...
Objective Acute exacerbations of idiopathic pulmonary fibrosis (AE-IPF) are fatal episodes acute respiratory worsening unknown etiology. Previous studies on distress syndrome have shown that direct hemoperfusion with a polymyxin B-immobilized fiber column (PMX-DHP) can beneficial effect the status. This retrospective study investigated prognosis and survival outcome patients AE-IPF who underwent PMX-DHP. Methods We examined records 50 treated in our hospital. All received corticosteroid...
Resveratrol, which is a polyphenol found in grapes, peanuts, and other plants, has health benefits for various chronic diseases. The aim of the present study was to examine effect resveratrol on cataract formation diabetic rats. Male Wistar rats (7-week-old) were treated with streptozotocin, streptozotocin-treated animals administered 5% D-glucose drinking water promote cataracts by inducing severe hyperglycemia. Resveratrol supplementation (10 or 30 mg/kg/d) initiated immediately after...
Abstract Although the 6 min walk test (6MWT) is well-established for assessing desaturation in patients with interstitial lung disease (ILD), it cannot be easily performed primary healthcare settings. This retrospective observational study aimed to evaluate usefulness of 1 sit-to-stand (1STST) during 6MWT ILD normal resting blood oxygen levels. We included 116 patients, and pulse saturation (SpO 2 ) both methods was analyzed. The SpO nadir 1STST correlated strongly (ρ = 0.82). frequency <...
This paper proposes human activity recognition based on the actual semantics of human's current location. Since no predefined location can adequately identify activity, we automatically from things by focusing association between and activities with things. Ontology is used to deal various possible representations (terms) each thing, identified a RFID tag, multi-class Naive Bayesian approach applied detect multiple terms. Our suitable for detecting even given variety object characteristics...
Adeno-associated virus (AAV) vector can efficiently transduce therapeutic genes in various tissue types with less side effects; however, owing to complex multistep processes during manufacture, there have been surges the pricing of recently approved AAV vector-based gene therapy products. This study aimed develop a simple and efficient method for high-quality purification via tangential flow filtration (TFF), which is commonly used concentration diafiltration solutions purification. We...
It has been suggested that nitric oxide (NO) stimulates the cyclooxygenase (COX)-dependent mechanisms in ocular vasculature; however, importance of pathway regulating retinal circulation vivo remains to be elucidated. Therefore, we investigated role COX-dependent NO-induced vasodilation blood vessels thiobutabarbital-anesthetized rats with and without neuronal blockade (tetrodotoxin treatment). Fundus images were captured a digital camera was equipped special objective lens. The vascular...