John Diks

ORCID: 0000-0003-1330-0232
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About
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Research Areas
  • Neuroendocrine Tumor Research Advances
  • Long-Term Effects of COVID-19
  • COVID-19 Clinical Research Studies
  • RNA modifications and cancer
  • Multiple and Secondary Primary Cancers
  • COVID-19 and healthcare impacts
  • Cancer Genomics and Diagnostics
  • Angiogenesis and VEGF in Cancer
  • Gastrointestinal Tumor Research and Treatment
  • Lymphoma Diagnosis and Treatment
  • Pancreatic and Hepatic Oncology Research
  • Axon Guidance and Neuronal Signaling
  • IgG4-Related and Inflammatory Diseases
  • Whipple's Disease and Interleukins
  • Lung Cancer Treatments and Mutations
  • Glycosylation and Glycoproteins Research
  • Genetic factors in colorectal cancer
  • Gastrointestinal disorders and treatments
  • Apelin-related biomedical research
  • Neurogenetic and Muscular Disorders Research
  • Gastric Cancer Management and Outcomes
  • Autoimmune Bullous Skin Diseases

The University of Texas MD Anderson Cancer Center
2023

SUNY Downstate Health Sciences University
2019-2022

State University of New York
2021-2022

Cairo University
2015

Abstract Background African-Americans/Blacks have suffered higher morbidity and mortality from COVID-19 than all other racial groups. This study aims to identify the causes of this health disparity, determine prognostic indicators, assess efficacy treatment interventions. Methods We performed a retrospective cohort clinical features laboratory data patients admitted over 52-day period at height pandemic in United States. was an urban academic medical center New York City, declared COVID-only...

10.1186/s12879-021-05782-9 article EN cc-by BMC Infectious Diseases 2021-01-18

More than 3.5 million people have died globally from COVID-19, yet an effective therapy is not available. It is, therefore, important to understand the signaling pathways that mediate disease progression in order identify new molecular targets for therapeutic development. Here, we report blood serum levels of ephrin-A1 and sheddase ADAM12 were significantly elevated COVID-19 patients treated at SUNY Downstate Hospital Brooklyn, New York. Both are known be involved inflammation regulate...

10.1016/j.heliyon.2021.e07200 article EN cc-by-nc-nd Heliyon 2021-05-31

ABSTRACT Background African-Americans/Blacks have suffered higher morbidity and mortality from COVID-19 than all other racial groups. This study aims to identify the causes of this health disparity, determine prognostic indicators, assess efficacy treatment interventions. Method We performed a retrospective cohort clinical features laboratory data patients admitted over five-week period at height pandemic in United States. was an urban academic medical center New York City, declared...

10.1101/2020.07.15.20154906 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2020-07-16

Abstract Background Genomic profiling is needed to identify actionable alterations in non–small cell lung cancer (NSCLC). Panel‐based testing such as next‐generation sequencing (NGS) often preferred interrogate multiple simultaneously. In this study, we evaluate the utility of an RNA‐based NGS assay detect genomic NSCLC cytology specimens and compare these results fluorescence situ hybridization (FISH) testing. Methods A retrospective review was performed 264 that were concurrently tested...

10.1002/cncy.22766 article EN Cancer Cytopathology 2023-09-25

Whipple's disease is a bacterial infection caused by Tropheryma whipplei and known to cause perplexing clinical presentations, making its diagnosis challenging. The beginning the involvement of gastrointestinal tract, can slowly progress affect almost any organ system lead chronic multi-system inflammatory disease. Hereby, we present middle age man who initially manifested with shortness breath weight loss. He subsequently developed pleuro-pericardial effusion, ascites, mesenteric...

10.12691/ajmcr-9-7-2 article EN American Journal of Medical Case Reports 2021-04-01

Introduction: Type 1 autoimmune pancreatitis (AIP) and idiopathic duct-centric chronic (IDCP) are distinct steroid-responsive fibro-inflammatory diseases of the pancreas that share overlapping features can be difficult to distinguish. Here, we describe an atypical presentation relapsing type AIP. Case Description/Methods: 65-year-old female with rheumatoid arthritis (RA) breast cancer status post lumpectomy, radiation, aromatase inhibition followed by Rheumatology. Therapy for RA was limited...

10.14309/01.ajg.0000779660.28150.05 article EN The American Journal of Gastroenterology 2021-10-01

Abstract Background: Despite advances in the treatment of classic Hodgkin lymphoma (CHL), current therapies fail to cure 10%-15% patients, and a similar proportion patients may be over treated, resulting both short-term long-term treatment-related complications. Current prognostic models predict outcome with imperfect accuracy, clinically relevant biomarkers have not been established improve on international score. Patients Methods: CD 68 protein RNA expression were assessed 81 Hodgkin's...

10.1158/1538-7445.am2015-2217 article EN Cancer Research 2015-08-01

INTRODUCTION: Gastrointestinal stromal tumors (GISTs) are a common mesenchymal tumor of the GI tract. Here we present case 60-year-old male with 33.5 × 27 cm GIST arising from greater stomach curvature, increased in size 18.1 13.4 five months; an alarming growth rate for known to grow slowly. CASE DESCRIPTION/METHODS: history and HTN presented hospital abdominal pain shortness breath. Physical exam revealed decreased bowel sounds diffuse tenderness palpation right left lower quadrants....

10.14309/01.ajg.0000600200.30431.35 article EN The American Journal of Gastroenterology 2019-10-01

Introduction: Two tumors having different histopathologies at anatomically distinct sites giving the picture of dual primary malignancies. Here we presented a case two possible and one secondary mass. Case Report: A 74-year-old female, active smoker, without personal or family cancer history with early satiety weakness for months. Systems review was positive “raw” feeling in stomach, alleviated antacids. Vital signs were stable negative abdominal exam. Lab showed leukocytosis 24.8 K/uL...

10.5348/100064z11el2022cr article EN cc-by 2022-12-22

Introduction: Two tumors having different histopathologies at anatomically distinct sites giving the picture of dual primary malignancies. Here we presented a case two possible and one secondary mass. Case Description/Methods: 74-year-old female, active smoker, without personal or family cancer history with early satiety weakness for months. Systems review was positive "raw" feeling in stomach, alleviated antacids. Vital signs were stable negative abdominal exam. Lab showed leukocytosis 24.8...

10.14309/01.ajg.0000784052.49425.00 article EN The American Journal of Gastroenterology 2021-10-01
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