Saba Ghaffary

ORCID: 0000-0003-1336-6039
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About
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Research Areas
  • Neutropenia and Cancer Infections
  • Antibiotics Pharmacokinetics and Efficacy
  • Attention Deficit Hyperactivity Disorder
  • COVID-19 Clinical Research Studies
  • Cardiac Ischemia and Reperfusion
  • Intensive Care Unit Cognitive Disorders
  • Natural Antidiabetic Agents Studies
  • Cardiac, Anesthesia and Surgical Outcomes
  • COVID-19 and healthcare impacts
  • Pain Mechanisms and Treatments
  • Bacterial Identification and Susceptibility Testing
  • Antibiotic Use and Resistance
  • Nutrition and Health in Aging
  • Mycobacterium research and diagnosis
  • Healthcare and Venom Research
  • Metabolism and Genetic Disorders
  • Bee Products Chemical Analysis
  • Mitochondrial Function and Pathology
  • Perfectionism, Procrastination, Anxiety Studies
  • Chemotherapy-related skin toxicity
  • Long-Term Effects of COVID-19
  • Cancer Treatment and Pharmacology
  • Anesthesia and Neurotoxicity Research
  • Neonatal and Maternal Infections
  • Iron Metabolism and Disorders

Tabriz University of Medical Sciences
2011-2025

University of Tabriz
2017

Tehran University of Medical Sciences
2015-2016

Farabi Hospital
2016

Heart failure is a root cause of morbidity and mortality worldwide. Due to the limited regenerative capacity heart following myocardial injury, stem cell-based therapies have been considered hopeful approach for improving cardiac regeneration. In recent years, different kinds cell products investigated regarding their potential treat patients with failure. Despite special attention therapy its products, therapeutic efficacy has disappointing, clinical application not affordable. past few...

10.1016/j.ijcha.2024.101399 article EN cc-by-nc IJC Heart & Vasculature 2024-03-30

Background: Okra (Abelmoschus esculentus) has garnered scientific attention for its beneficial effects on various chronic disorders, including type 2 diabetes mellitus. Objectives: The current study was designed and conducted to assess the influence of whole okra fruit powder serum levels specific biochemical parameters in individuals with pre-diabetes. Methods: Seventy pre-diabetic patients, aged 30 - 55 years, were divided into two groups: group (n = 35, fasting plasma glucose: 116.26 ±...

10.5812/jjnpp-143074 article EN Jundishapur Journal of Natural Pharmaceutical Products 2024-01-23

Abstract Okra ( Abelmoschus esculentus ) has traditionally been used in diabetes treatment. This study investigated the effect of whole fruit on blood glucose level patients with mellitus type 2 concomitant use oral hypoglycemic agents. In this double‐blind randomized clinical trial, 120 diabetic were assigned to okra group n = 60) and control 60). The received 1,000 mg A.esculentus capsules orally, every 6 hr for 8 weeks. placebo capsule same manner. levels FBS (fasting sugar), BS (blood...

10.1002/ptr.7341 article EN Phytotherapy Research 2022-03-18

ABSTRACT Introduction Hypersensitivity reactions (HSRs), an unpredictable and sometimes harmful reaction, may hamper the effectiveness of chemotherapy lead to need for drug switching. The recall ranitidine from market due N ‐nitrosodimethylamine production necessitates identification a proper alternative prevention HSRs. Our study aimed evaluate efficacy oral famotidine in HSRs patients who received agents, particularly platinum‐based taxanes. Methods A total 426 were treated with agents or...

10.1111/ajco.14154 article EN Asia-Pacific Journal of Clinical Oncology 2025-02-04

Post-operative cognitive dysfunction (POCD) is an important complication of cardiac surgeries. Glutamate plays a critical role in physiologic and pathologic conditions the brain. Due to glutamate ischemia, this study designed identify effect memantine prevention POCD early late after In randomized clinical trial, 172 patients with ages 45–75 years old who underwent elective surgery were enrolled. For group, 5 mg per day administered at least 48 h before increased 10 during first 24 continued...

10.1186/s40199-017-0190-0 article EN cc-by DARU Journal of Pharmaceutical Sciences 2017-11-21

Exhaled breath condensate (EBC) has been proposed as an alternative non-invasive biological sample for therapeutic drug monitoring.

10.1039/c7ay01715d article EN Analytical Methods 2017-01-01

Purpose . To evaluate the difference in biomechanical properties between contact lens induced corneal warpage and normal keratoconic eyes. Method Prospective observational case control study, where 94 eyes of 47 suspicious 46 23 patients were included. Warpage suspected cases followed until a definite diagnosis was made (warpage, normal, or keratoconus). Results 44 22 had related warpage. people diagnosed as nonwarpage known keratoconus included for comparison. The mean age participants 23.8...

10.1155/2016/5603763 article EN cc-by Journal of Ophthalmology 2016-01-01

Background Diabetes patients frequently experience diabetic neuropathy (DN), a microvascular complication that significantly reduces patients’ quality of life. Memantine has demonstrated potential benefits for neuropathic pains in preclinical studies. This study aimed to assess the efficacy memantine management peripheral with type 2 diabetes mellitus (T2DM). Method randomized clinical trial includes 143 (aged between 18 and 75 years) confirmed diagnosis neuropathy. Patients were randomly...

10.1177/14791641231191093 article EN cc-by-nc Diabetes and Vascular Disease Research 2023-07-01

Objectives: Oral mucositis is a chemotherapy adverse effect. Because of anti-inflammatory, wound-healing, and antimicrobial effect Achillea millefolium, the current research assessed effectiveness millefolium mouthwash on prevention treatment oral mucositis, induced by in patients with acute myeloid leukemia. Methods: From 29 patients, who received induction or consolidation regimen, 14 intervention 15 control groups, were randomly assigned this study. The group gargled 10 mL plus...

10.5812/jjnpp.14077 article EN Jundishapur Journal of Natural Pharmaceutical Products 2019-01-09

Serum sodium (Na) concentration more than 145 mmol/L is defined as hypernatremia. Hypernatremia carries an acute morbidity and mortality, especially in neonates infants. Rapid correction of hypernatremia leads to severe cerebral damages, seizure the most common neurological complication Selection calculation appropriate fluid its amount one tremendous challenges. It important choose correct suitable adjust rehydration rate. In this study, we have suggested practical equation determine that...

10.4103/2279-042x.200988 article EN cc-by-nc-sa Journal of Research in Pharmacy Practice 2017-01-01

Background: There is a relation between amounts of antibiotic uses and creation resistant bacteria. Due to the critical role antibiotics increasing trend resistance in developing countries, comprehensive methods use necessary limit threat microorganisms. In this study we compare consumption by Defined Daily Dose (DDD) per 100 bed-days teaching private hospitals during six months Tabriz, Iran. Methods: Four university one hospital were included study. Amount their obtained from pharmacies....

10.15171/ps.2017.06 article EN cc-by-nc Pharmaceutical Sciences 2017-03-30

Purpose: The aim of the study is to evaluate effect metformin in complication improvement hospitalized patients with COVID-19. Methods: This was a randomized clinical trial that involved 189 confirmed COVID-19 infection. Patients intervention group received metformin-500 mg twice daily. who before admission were excluded from control group. discharged taking at least 2000 study. Primary outcomes vital signs, need for ICU admission, intubation, and mortality. Results: Data showed diabetes...

10.34172/apb.2023.066 article EN cc-by Advanced Pharmaceutical Bulletin 2022-07-02

Background: Varicella-Zoster virus (VZV) is the causative agent of herpes zoster, or "shingles." Most cases acute zoster are self-limiting, although pain can cause significant suffering, and experience postherpetic neuralgia (PHN), particularly in older adults. Early treatment herpetic subacute phase may prevent PHN progression. This study aimed to evaluate efficacy memantine neuropathic zoster. Methods: randomized clinical trial was performed on sixteen patients aged 18-75 years with...

10.18502/jpc.v10i4.11579 article EN cc-by-nc Journal of Pharmaceutical Care 2023-01-02

Background: Effective clinical care and identifying susceptibility to COVID-19-related mortality requires rapid recognition of risk factors their relations with disease outcomes. This study aimed cluster identify various subgroups COVID-19 patients examine the relationship between these causes death. Methods: retrospective assessed contributing patients’ death (n = 128) by evaluating deceased patients' demographic, clinical, laboratory features clustering individuals investigate any...

10.18502/jpc.v11i1.12636 article EN cc-by-nc Journal of Pharmaceutical Care 2023-05-03
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