Zhenfeng Guo

ORCID: 0000-0003-1340-1308
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Research Areas
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Traditional Chinese Medicine Analysis
  • Lymphoma Diagnosis and Treatment
  • Traditional Chinese Medicine Studies
  • Venous Thromboembolism Diagnosis and Management
  • Streptococcal Infections and Treatments
  • Nephrotoxicity and Medicinal Plants
  • Renal function and acid-base balance
  • Metabolism, Diabetes, and Cancer
  • Infective Endocarditis Diagnosis and Management
  • Neonatal Respiratory Health Research
  • Blood Coagulation and Thrombosis Mechanisms
  • Plant-based Medicinal Research
  • Intracranial Aneurysms: Treatment and Complications
  • Ocular Surface and Contact Lens
  • Transplantation: Methods and Outcomes
  • Vector-borne infectious diseases
  • Leptospirosis research and findings
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Cardiac Structural Anomalies and Repair
  • Corneal Surgery and Treatments
  • Retinal and Optic Conditions
  • Acute Myocardial Infarction Research
  • Cardiovascular Function and Risk Factors

Tianjin Beichen Hospital
2014-2024

Nankai University
2024

Nanjing Medical University
2011-2023

Tianjin Medical University Eye Hospital
2010-2022

Tianjin Medical University
2010-2022

Uveitis is a not uncommon potentially sight-threatening intraocular inflammatory disorder and major cause of blindness worldwide. Early diagnosis effective treatment are very important to reduce complications protect vision.In retrospective series, we enrolled 263 (390 eyes) consecutive uveitis patients, comprising 126 males 137 females. The clinical types uveitis, efficacy, visual prognosis were evaluated by detailed examination, laboratory tests observation.There 101 cases panuveitis...

10.21037/apm-21-3549 article EN Annals of Palliative Medicine 2021-12-01

Scrub typhus is a zoonotic disease caused by Orientia tsutsugamushi, gram-negative intracellular bacterium and endemic in Asia-Pacific area. Acute myocardial infarction after Oricntia tsutsugamushi infection was rarely reported, young adult not reported.A 33-year-old man came to the emergency complained with chest tightness fever for 4 days.After Weil-Felix agglutination test (titer 1:160) twice, scrub diagnosed.After treating hormonotherapy, antibiotic ventilator-assisted ventilation, his...

10.1097/md.0000000000035271 article EN cc-by-nc Medicine 2023-09-29

This study aimed to explore the pterygium formation and recurrence, by detecting expression of Nod-like receptor pyrin domain 3 (NLRP3) 6 (NLRP6) in evaluate correlation between NLRP3 NLRP6 pterygium.In this prospective study, levels NLRP6, with their related effectors, were evaluated primary (n = 40) recurrent 32) tissue samples compared normal conjunctiva 11) immunohistochemistry.Compared group, NLRP3, caspase-1, IL-18, IL-1β, significantly higher, showed an that was lower (P < 0.05,...

10.1177/11206721221074200 article EN European Journal of Ophthalmology 2022-01-24

Abstract The study aimed to assess the effect and mechanism of safflower injection in preventing retinal vein thrombosis rabbits. Twenty healthy adult pigmented rabbits were randomly assigned either experimental group, receiving injection, or control normal saline. After two weeks treatment, blood samples collected analyze platelet adhesion aggregation rates. Photodynamic therapy was applied induce occlusion target vein. Fundus photography fluorescein angiography recorded using a dynamic...

10.1038/s41598-024-58734-z article EN cc-by Scientific Reports 2024-04-05

To evaluate the effects and mechanisms of glucose-insulin-potassium (GIK) on post-procedural myocardial injury (PMI) after percutaneous coronary intervention (PCI).A total 200 non-diabetic patients with documented heart disease (CHD) were divided into Group GIK G, 100 in each group. Patients G given intravenous infusion glucose solution 2 hours before PCI. As compared, GIK.Both creatine phosphokinase isoenzyme MB (CK-MB; 62.1 ± 47.8 vs. 48.8 52.6 U/L, P = 0.007) cTnI (0.68 0.83 0.19 0.24...

10.11909/j.issn.1671-5411.2020.09.004 article EN PubMed 2020-09-28

Objective To explore the recurrence and poor prognosis mechanism from perspective multi-drug resistance (MDR) by detecting expression of P-gp,GST-π LRP in orbital lymphoma.Methods Fifty lymphoma tissue which were diagnosed pathology after surgery collected Tianjin eye hospital first centre hospital.Among them,46 cases observation group.Meanwhile,17 reactive lymphoid hyperplasia tissues as contrast group.Orbital microarray immunohistochemical staining was used to detect hyperplasia.Results...

10.3760/cma.j.issn.1006-4443.2014.06.020 article EN Chinese Journal of Practical Ophthalmology 2014-06-10

A 23-year-old male with no history of heart disease was admitted to our hospital for an abnormal electrocardiogram ST-T changes mimicking myocardial infarction. Catheterisation revealed totally normal coronary and peripheral arteries. The echocardiogram delayed enhancement cardiovascular magnetic resonance imaging indicated a markedly reduced left ventricular function enlarged cavity evidence necrotic myocardium. Giving the patient9s multiple blunt trauma 7 years ago ‘acute infarction’...

10.1136/heartjnl-2011-300867.615 article EN Heart 2011-10-01

Objective To probe the color Doppler imaging (CDI) characteristics of orbital and ocular adnexal lymphoma. Methods The CDI 30 cases (30 eyes) lymphoma including clinical manifestation occurrence sites were analyzed retrospectively from 2005 to 2009 at Tianjin Eye Hospital. All diagnosed by postoperative pathologic diagnosis. Results Thirty lymphomas occurred in orbit, conjunctiva, lacrimal gland sac. Most them our with anteroposterior diameter longer than 1cm, irregular shape, unclear margin...

10.3760/cma.j.issn.1006-4443.2010.10.014 article EN Chinese Journal of Practical Ophthalmology 2010-10-10

Objective To investigate the effect of hematoma puncture and clearance on neurological cognitive function in patients with cerebral hemorrhage. Methods The clinical data 116 hemorrhage treated Linfen People’s Hospital from July 2015 to February 2018 were retrospectively analyzed. According surgical treatment schemes, selected divided into control group (hematoma clearance, 58 cases) observation puncture, cases). The two groups compared. Results Before treatment, there was no...

10.3760/cma.j.issn.1674-4756.2019.13.016 article EN Central Plains Medical Journal 2019-07-10
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