- Stress Responses and Cortisol
- Ear and Head Tumors
- Sarcoma Diagnosis and Treatment
- Oral and Maxillofacial Pathology
- Viral-associated cancers and disorders
- Cancer, Stress, Anesthesia, and Immune Response
- Tumors and Oncological Cases
- Salivary Gland Tumors Diagnosis and Treatment
- Oral and gingival health research
- Parvovirus B19 Infection Studies
- Biochemical effects in animals
- Lymphoma Diagnosis and Treatment
- Pain Management and Opioid Use
- Neuropeptides and Animal Physiology
- Histiocytic Disorders and Treatments
- Tryptophan and brain disorders
- Cardiac tumors and thrombi
- Oral Health Pathology and Treatment
- Nerve Injury and Rehabilitation
- Vascular Malformations Diagnosis and Treatment
- Effects of Radiation Exposure
- Neuroblastoma Research and Treatments
- Sleep and related disorders
- Chemokine receptors and signaling
- Trigeminal Neuralgia and Treatments
Universidade Estadual Paulista (Unesp)
2020-2025
Social isolation has affected a large number of people and may lead to impairment physical mental health. Although stress resulting from social increase cancer progression, its interference on tumorigenesis is poorly known. In this study, we used preclinical model evaluate the effects chemically induced oral carcinogenesis. Sixty-two 21-day-old male Wistar rats were divided into isolated grouped groups. After 90 days age, both groups underwent carcinogenesis with 4-nitroquinoline 1-oxide...
ABSTRACT Background This exploratory cross‐sectional observational study sought to characterize sleep quality and evaluate its association with sociodemographic, clinicopathological, behavioral, psychological variables in patients head neck squamous cell carcinoma (HNSCC). Patients Methods Sleep problems from 132 HNC were assessed before starting oncological treatment through the questionnaires Pittsburgh Quality Index (PSQI), Insomnia Severity (ISI), Epworth Sleepiness Scale (ESS),...
Pain associated with head and neck cancer (HNC) is difficult to manage reduces quality of life. It has been increasingly recognized that HNC patients exhibit a wide range pain symptoms. Here we developed an orofacial assessment questionnaire conducted pilot study improve phenotyping in at the diagnosis. The captures following characteristics: intensity, location, quality, duration, frequency; impact on daily activities; changes smell food sensitivities. Twenty-five completed questionnaire....
Abstract Chronic stress increases the systemic levels of hormones norepinephrine and cortisol. As well as tobacco-specific carcinogen NNK (4-(methylnitrosamine)-1-(3-pyridyl)-1-butanone), they can induce expressive DNA damage contributing to cancer development. However, it is unknown whether have genotoxic effects in oral keratinocytes. This study investigated on a human keratinocyte cell line (NOK-SI). NOK-SI cells stimulated with or cortisol showed higher compared untreated cells....
Clinical investigations suggest that melatonin suppression and circadian dysfunction may be related to cancer development in shift workers. Studies also show after pinealectomy increases incidence preclinical models. However, no study evaluated the influence of on oral development. In current study, we investigated effects squamous cell carcinoma (OSCC) occurrence progression rats. Rats submitted sham surgery were used as control. Pinealectomy promoted an increase 140% OSCC when compared...
Venous malformations (VMs) are congenital disorders that constitute about 40% of all vascular anomalies. These lesions do not regress spontaneously and may increase in size during childhood. The case a 10-year-old girl with an extensive oral VM is reported. Intraoral examination revealed the presence purplish nodules alveolar mucosa gingiva from anterior maxilla. Doppler ultrasound showed well-defined hypoechoic image increased vascularization low blood flow for lesion. patient was submitted...
To evaluate the influence of early life stress (ELS) on severity apical periodontitis (AP) in Wistar rats.Forty male rats were divided into four groups (n = 10): Control rats; AP-rats with AP; ELS-rats subject to ELS; AP + exposed ELS and AP. was induced by maternal separation (MS) for a period 3 h 21 consecutive days. via pulp exposure first second right maxillary molars oral environment 40 Three days before euthanasia, all underwent behavioural analysis measure anxiety levels elevated zero...