Ioana Onac

ORCID: 0000-0003-1361-4098
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About
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Research Areas
  • Musculoskeletal pain and rehabilitation
  • Spine and Intervertebral Disc Pathology
  • Vasculitis and related conditions
  • Inflammatory Bowel Disease
  • Otitis Media and Relapsing Polychondritis
  • Mindfulness and Compassion Interventions
  • Psoriasis: Treatment and Pathogenesis
  • Electromagnetic Fields and Biological Effects
  • Insect and Pesticide Research
  • Platelet Disorders and Treatments
  • Rabbits: Nutrition, Reproduction, Health
  • Myofascial pain diagnosis and treatment
  • Food Industry and Aquatic Biology
  • Cancer Diagnosis and Treatment
  • Adrenal Hormones and Disorders
  • Osteoarthritis Treatment and Mechanisms
  • Pain Management and Placebo Effect
  • Spondyloarthritis Studies and Treatments
  • Immunodeficiency and Autoimmune Disorders
  • Sarcoidosis and Beryllium Toxicity Research
  • Kawasaki Disease and Coronary Complications
  • Exercise and Physiological Responses
  • Streptococcal Infections and Treatments
  • Infectious Diseases and Tuberculosis
  • Magnetic and Electromagnetic Effects

Surrey and Sussex Healthcare NHS Trust
2022

King's College London
2021

King's College Hospital
2020

Princess Royal Hospital
2014

Carol Davila University of Medicine and Pharmacy
2001

Hai phong University Of Medicine and Pharmacy
1999

Real-world secukinumab gastrointestinal-related adverse events (GIRAE) data during treatment for AS and PsA are lacking. We aimed to obtain this through baseline evaluation of pre-existing IBD rates predictors GIRAE.Patient electronic paper records commencing from 10 UK hospitals between 2016 2019 were reviewed. GIRAE after initiation defined as: definite [objective evidence (biopsy proven), clear temporal association, resolution symptoms on drug withdrawal, no alternative explanation felt...

10.1093/rheumatology/keab193 article EN Lara D. Veeken 2021-02-28

We studied the changes occurring in metabolism of proteins (serum cholinesterase, total proteins) and glycosides glucose) Cavia cobaia. The result this simple blind study was evaluated on first, tenth twentieth days treatment. A Duncan test used for graphical statistical analysis data. technique treatment doses were similar all groups, laser treated, red light controls. In groups treated with He-Ne laser, serum cholinesterase levels increased proportionately dose, reaching a peak day 10,...

10.5978/islsm.11.130 article EN LASER THERAPY 1999-01-01

The aim of the study was to assess effects therapeutic ultrasound (US) on oxidative stress (OS)-induced changes in cultured human chondrocytes (HCH). For this, monolayer HCH were randomized three groups: a control group (CG), exposed OS (OS group), and US (US-OS group). exposure performed prior induction by hydrogen peroxide. Transmission electron microscopy (TEM) used ultrastructure. inflammatory markers recorded. Malondialdehyde (MDA) tumor necrosis factor (TNF)-α significantly higher (p...

10.3390/app12052334 article EN cc-by Applied Sciences 2022-02-23

Numerous post-Streptococcal syndromes (PSS) have been described in the literature. The role of antibiotic therapy management PSS is best established with acute rheumatic fever. We present a patient streptococcus-associated medium vessel vasculitis multiple flares despite immunosuppressive that achieved sustained remission long term oral penicillin V 250 mg twice daily.

10.1016/j.idcr.2021.e01071 article EN cc-by-nc-nd IDCases 2021-01-01

Abstract Introduction This case describes a very aggressive form of giant cell arteritis (GCA) complicated by ocular ischaemic syndrome (OIS), complete bilateral visual loss and scalp muscle necrosis, despite treatment with high dose intravenous steroids. OIS, defined as ischaemia all intraorbital intraocular structures, is rare, estimated at 7.5 cases per million. also highlights the use PET CT in management complex GCA. Case description A 79-year-old lady presented sudden onset pain above...

10.1093/rap/rkz028.002 article EN cc-by-nc Rheumatology Advances in Practice 2019-09-01

We checked the changes occurring in metabolism of proteins (seric cholinesterase, total proteins) and glycosides glucose) Cavia cobaia. A simple blind study was carried out results were on first, tenth twentieth days treatment. The data thus obtained graphically represented statistically processed according to Duncan test. technique treatment doses similar they compared with from controls environment controls. In groups biostimulated He-Ne laser, seric cholinesterase levels increased...

10.1117/12.432909 article EN Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE 2001-06-29

Abstract Case report - Introduction Bacterial and fungal infections are recognised complications of viral pneumonia, particularly in patients who critically ill. We describe a case sacroiliitis complicating severe COVID-19 pneumonia following prolonged intensive care unit (ICU) admission. Candida albicans sacroilitis is rarely reported infection with few reports the literature. osteoarticular can present as septic arthritis, knee involvement 75% cases, or osteomyelitis. The latter...

10.1093/rap/rkaa052.012 article EN cc-by Rheumatology Advances in Practice 2020-10-01

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)

10.1530/endoabs.34.p306 article EN Endocrine Abstracts 2014-03-01

<h3>Background</h3> Temporal arteritis (TA) is the commonest vasculitis characterised by inflammation of large and medium vessels. It predominantly affects cranial arteries arising from aortic arch requires early recognition treatment to ensure avoidance ischaemic neuro-ophthalmic complications. <h3>Objectives</h3> 100% compliance with British Society Rheumatology guidelines for TA: Ø Diagnosis criteria Urgent referral specialist evaluation Inflammatory markers checked before steroid started...

10.1136/annrheumdis-2016-eular.4247 article EN Annals of the Rheumatic Diseases 2016-06-01

Abstract Background Secukinumab is a selective interleukin-17a inhibitor (anti-IL17) and an effective treatment option for psoriatic arthritis (PsA) ankylosing spondylitis (AS). Phase III study safety data indicate possible risk of inflammatory bowel disease (IBD), link which biologically plausible as IL-17 known to influence intestinal immunopathology. Real world secukinumab gastrointestinal are limited. We set out describe the post-licensing experience in routine care, evaluating both...

10.1093/rheumatology/keaa110.018 article EN Lara D. Veeken 2020-04-01

Abstract Case report - Introduction Sarcoidosis is a multisystem disorder of unknown aetiology that characterised pathologically by the presence non-caseating granulomata. The disease known for its multitude presentations and can affect almost any organ system. Symptomatic skeletal muscle involvement in sarcoidosis infrequent occurs &amp;lt; 3% all patients. We present case 47-year-old male with involving his lungs, eyes, liver, who presented to our tertiary sarcoid centre proximal weakness....

10.1093/rap/rkaa052.022 article EN cc-by Rheumatology Advances in Practice 2020-10-01
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