A5080165517- Antioxidant Activity and Oxidative Stress
- Oral microbiology and periodontitis research
- Liver Disease Diagnosis and Treatment
- Global Health Workforce Issues
- Adipokines, Inflammation, and Metabolic Diseases
- Nanoparticles: synthesis and applications
- Migration, Health and Trauma
- Medical Education and Admissions
- Health, psychology, and well-being
- Innovations in Medical Education
- Exercise and Physiological Responses
- Natural Antidiabetic Agents Studies
- Mental Health Treatment and Access
- Heme Oxygenase-1 and Carbon Monoxide
- Osteoarthritis Treatment and Mechanisms
- Laser Applications in Dentistry and Medicine
- Biochemical effects in animals
- Child and Adolescent Psychosocial and Emotional Development
- High Altitude and Hypoxia
- dental development and anomalies
- Salivary Gland Disorders and Functions
- Phytochemicals and Antioxidant Activities
- Diet, Metabolism, and Disease
- Anatomy and Medical Technology
- Quantum Information and Cryptography
Iuliu Hațieganu University of Medicine and Pharmacy
2015-2025
Hôpital d'Hautepierre
2024
Horia Hulubei National Institute for R and D in Physics and Nuclear Engineering
2023
University of Bucharest
2023
University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca
2008-2020
Mitsubishi Corporation (United States)
2014
Institutul Clinic Fundeni
2011
Universidade de São Paulo
2010
Migration of healthcare workers is receiving increased attention worldwide. In Europe, the creation a border-free labor market and its expansion with EU enlargements 2004, 2007, 2013 endowed health professionals right to provide services relocate another Member State. For Romanian doctors, EU-wide recognition medical degree obtained in Romania has created new opportunities, while inadequate working conditions relatively low salaries pushed many them search for employment abroad. As there...
Nigella sativa (NS) has been used for centuries in various inflammatory conditions because of its anti-inflammatory and antioxidant activities. The study aimed to evaluate the anti-inflammatory, antinociceptive activity oil (NSO) two models acute (carrageenan-induced) sub-acute inflammation (complete Freund’s adjuvant induced) rats. Materials Methods: NSO was administered orally 1, 2 4 mL/kg phase. For subacute phase, mL/kg, 7 days before or after induction, association with diclofenac 5...
Morbid obesity represents a proinflammatory and pro-oxidative state associated with dysregulation of adipokines. We aimed to evaluate the circulating levels chemerin omentin-1 in morbidly obese (MO) patients investigate relationship between these two adipokines each them anthropometric, metabolic, oxidative stress chronic inflammatory parameters.32 MO 20 controls were investigated this study. Anthropometric, metabolism parameters, markers, indicators as well measured.Serum increased while...
Schiff bases (SBs) are chemical compounds displaying a significant pharmacological potential. They able to modulate the activity of many enzymes involved in metabolism and found among antibacterial, antifungal, anti-inflammatory, antioxidant, antiproliferative drugs. A new thiazolyl-triazole SB was obtained characterized by elemental spectral analysis. The antibacterial antifungal ability evaluated against Gram-positive Gram-negative bacteria three Candida strains. showed good L....
Background and Objectives: The study investigates the relationship between accessible biomarkers extent of lung damage, assessed with computed tomography (CT) imaging, in patients hospitalized for COVID-19. Materials Methods: This retrospective analysis was conducted a hospital Cluj-Napoca, Romania, it includes 111 diagnosed moderate to severe forms COVID-19 during Delta Omicron waves. We evaluated association affordable lab works, such as C-reactive protein (CRP), procalcitonin, ferritin,...
BACKGROUND Curcumin is an antioxidant that reduces inflammation and pain. This study aimed to assess the effect of pretreatment with naproxen liposomal curcumin compared solution on oxidative stress parameters pain in a rat model migraine. MATERIAL AND METHODS Sixty-three male Wistar rats included control group (n=9) migraine (n=54) induced by intraperitoneal injection nitroglycerin (1 mg/0.1 kg). The was divided into untreated (n=9), pretreated alone (2.8 mg/kg) combined kg) (2 (n=9)....
Cornus mas L. extract (CM) presents hypolipidemic, antioxidant and anti-inflammatory activity. Gold nanoparticles (AuNPs) are considered potent delivery systems may be used to release pharmaceutical compounds at the level of injury. In our study, we gold functionalized with bioactive from (AuNPsCM) in an experimental model a high-fat diet (HFD), assessed their effects on aorta wall but also serum, as compared administration. Sprague Dawley female rats were fed for 9 months HFD. During last...
Osteoarthritis (OA) is the most prevalent chronic joint disease, increases in prevalence with age, and affects individuals over 65. The present study aimed to assess oxidative status relation diet physical activity patients OA. We used a cross-sectional applied 98 females Blood samples were collected determine stress markers: malonyl dialdehyde (MDA), reduced glutathione (GSH), oxidized (GSSG), GSH/GSSG. Diet was estimated standardized food frequency questionnaire. International Physical...
Background and Objectives: The ongoing COVID-19 pandemic has posed an array of new challenges for medical students worldwide. Amidst academic rigors, are confronted with unique stressors, potentially affecting their mental health substance use. This study aimed to investigate the multifaceted effects depression, alcohol use, stress on discern how these factors have been amplified by pandemic's circumstances, identify predictors distress during period. Materials Methods: Two online anonymous...
Metabolic syndrome (MetS) has been associated with left ventricular diastolic dysfunction (LVDD) preserved systolic function. This study aims at identifying the predictive factors for LVDD in MetS patients.The studied group comprised 72 consecutive hospitalized patients (2010-2011) diagnosed based on AHA/NHLBI/IDF 2009 definition, free of cardiovascular disease (36.11% males, age 59.19 ± 5.26 years), who underwent echocardiographic examination. Laboratory measurements high-sensitivity...
This study focuses on the assessment of attitudes and practices regarding research among undergraduate medical students from Cluj-Napoca, Romania.A cross-sectional was performed thorough anonymous questionnaires (May-June 2018) 510 third- fifth-year Iuliu Hatieganu University Medicine Pharmacy Romania.More than 60% declared that they were interested willing to perform during studies, while more two-thirds in doing so after graduation. In total, 6% third-year 31% had prepared a scientific...
Fluoropyrimidines represent the backbone of many chemotherapy protocols and standard treatment for types tumors. Toxicity associated with fluoropyrimidines can occur in up to 40% cases.The objective this study was analyze correlation between plasma concentration 5-fluorouracil adverse events that patients might experience during therapy.A total 58 received 5-fluorouracil-based chemotherapy. A blood sample collected from each patient drug infusion, order assess area under curve...
Stigmatizing attitudes to mental illness, and especially schizophrenia, are not limited the general population but also common among health professionals. Health professionals in a position model related both public patients. Medical students an interesting group focus upon, since they future correcting stigmatizing is still possible during their educational curriculum.This study investigated attitude toward illness medical at Iuliu Hatieganu University of Medicine Pharmacy. We surveyed...
To estimate the effects of hydroethanolic red grapes seeds extract obtained from Vitis vinifera, Burgund Mare variety, Recaş , Romania (BMR) on oxidant-antioxidant ballance, as compared to ascorbic acid, during pregnancy in rats. Thirty Wistar female rats were assigned three groups (n=10) which administered by gavage: Group I, 3 × 100 mg/kg body weight saline, II — BMR 30 mg gallic acid equivalents/kg weight; III vitamin C days 1, 7 and 14 pregnancy. On day 21 blood samples collected. Malon...
The seed extract (GSE) of Burgund Mare de Recas grape variety was evaluated for antitumor activity against Ehrlich ascites carcinoma(EAC)-bearing Swiss albino mice. antioxidant GSE also estimated in EAC-bearing mice treated with doxorubicin 2x0.1 mg/mouse. composition polyphenols the GSE, expressed as gallic acid, consisted 11.477mg/l. anti-tumor assessed by measuring tumor volume and counting cells. As oxidative stress parameters total thiobarbituric reactive substances (TBARS) plasma were...
Abstract Serum paraoxonase-1 (PON1) binds mainly to high density lipoproteins (HDLs) and protects low (LDLs) against oxidation. While paraoxonase arylesterase activities are traditionally assayed, lactonase activity, accounting for protection LDL oxidation, was less investigated in obese children adolescents. Therefore, we aimed measure lactonase, activities, oxidized (ox-LDL) malondialdehyde (MDA) levels Study population included 68 (35 33 normal-weight). Arylesterase were assayed...