A5101941917- Inflammatory Bowel Disease
- Nutritional Studies and Diet
- Essential Oils and Antimicrobial Activity
- Pharmacological Effects of Natural Compounds
- Obesity, Physical Activity, Diet
- Analytical Methods in Pharmaceuticals
- Nutrition, Genetics, and Disease
- Drug Solubulity and Delivery Systems
- Eosinophilic Esophagitis
- Microscopic Colitis
- Vitamin C and Antioxidants Research
- Antioxidant Activity and Oxidative Stress
- Bipolar Disorder and Treatment
- Immunodeficiency and Autoimmune Disorders
- Maternal and Perinatal Health Interventions
- Reproductive Health and Contraception
- Breast Lesions and Carcinomas
- COVID-19 and healthcare impacts
- COVID-19 Impact on Reproduction
- Schizophrenia research and treatment
- Pregnancy and preeclampsia studies
- Diet and metabolism studies
- Maternal and fetal healthcare
- Reproductive Health and Technologies
- Cancer and Skin Lesions
Carol Davila University of Medicine and Pharmacy
2008-2025
Centre Hospitalier Régional Universitaire de Brest
2024
Hôpital Maison Blanche
2024
University of Bucharest
2023
UCB Pharma (United States)
2020-2021
Clinical Emergency Hospital Bucharest
2021
Arad County Clinical Hospital
2021
Spitalul Clinic de Psihiatrie Alexandru Obregia
2020
Wayne State University
1999
Sinai Hospital
1999
Background and Objectives: This study aims to assess the health status factors influencing healthy choices among children young people in Romania, as well efficacy of related education programs. Through understanding these dynamics, seeks provide insights that can shape targeted interventions, policies, educational strategies improve this demographic’s overall well-being. Materials Methods: For study, we performed a literature review original published papers on status, habits, education,...
Nutriepigenetics, the study of nutritional effects on gene expression, offers new insights into clinical variability and relapse frequency inflammatory bowel disease (IBD). As older adult populations are frequently unrepresented in literature regarding their nutrition's influence we considered that studying this aspect would shed light population group. We conducted a prospective observational 60 IBD patients, categorized by age, residence, nutrition access. Patients were grouped according...
Background and objectives: The primary oral disease during adolescence is dental caries. Less known about the caries prevalence, health behavior, sweets nutritional habits in Romanian adolescents. objective of this study was to assess actual prevalence among adolescents a representative area Romania, Cluj, correlate with hygiene behaviors dietary sugary foods intake. Materials methods: We have done cross-sectional 650 aged 10 19-years-old (average age 15.3 ± 2.8). performed examination...
Alcohol consumption is a major public health problem facing universities. The objectives of the present study were to investigate alcohol and behaviors associated with it among Romanian university medical students, particular reference sex differences, behavioral consequences, lifestyle patterns. We performed cross-sectional on 722 students (60.4% females; 39.6% males); participants filled out validated questionnaire containing following items co-occurring consumption: smoking, illicit drug...
Poor eating habits and substance abuse are major public health concerns among young adults transitioning into university life. This study’s objective was to assess Romanian students’ alcohol consumption correlate it with other lifestyle factors. We performed a cross-sectional study of 1212 students mean age 21.1 ± 2.4 years. applied valid online questionnaire evaluate statistically analyze the interrelation between factors by multivariate statistical analysis. The prevalence student...
The use of gentamicin (GM) is limited due to its nephrotoxicity mediated by oxidative stress. This study aimed evaluate the capacity a flavonoid-rich extract Sambucus nigra L. elderflower (SN) inhibit lipoperoxidation in GM-induced nephrotoxicity. HPLC analysis SN recorded high contents rutin (463.2 ± 0.0 mg mL-1), epicatechin (9.0 1.1 µg and ferulic (1.5 0.3 mL-1) caffeic acid (3.6 0.1 mL-1). Thirty-two Wistar male rats were randomized into four groups: control group (C) (no treatment), GM...
Alpha-lipoic acid (ALA, thioctic acid), a naturally-occurring essential dithiol compound, has become common ingredient in many pharmaceutical and food supplement products (FSP), used oxidative stress-dependent pathologies; oral bioavailability of ALA is limited by pharmacokinetic particularities that reduce its therapeutic efficacy-reduced solubility, lack gastric stability hepatic degradation, doubled formulation hinders. The objectives were to develop solid 600 mg FSP obtain an optimal...
Vitamin C is indispensable for the normal functioning of most important biological processes in human body and plays an essential role immune response to stress viral bacterial infections.Hesperidin a bioflavonoid with vascularprotecting anti-inflammatory properties.Given benefits vitamin hesperidin increased absorption by bioflavonoids, dietary supplement containing both active ingredients has been developed improve system.Calcium ascorbate was used intake reduce high acid side effects at...
Immature sacrococcygeal teratoma represents a histological form with rapid tumor growth, risk of premature birth, an enhanced rate complications, increased recurrence, and higher mortality than the mature type. Thus, prenatal diagnosis immature forms would significantly improve prognosis these cases. To this end, we performed extensive literature review on diagnosis, therapeutic management, follow-up teratomas. Regarding medical conduct, also presented our case. In conclusion, early...
Tablet manufacturing involves the processing of raw materials through several unit operations. Thus, mitigation input-induced variability should also consider downstream processability intermediary products. The objective present work was to study effect variable and conditions on compression properties granules containing two active pharmaceutical ingredients (APIs) microcrystalline cellulose. Differences in compressibility tabletability were highlighted function initial particle size first...
Osteoarthritis (OA) is the most prevalent chronic joint disease, increases in prevalence with age, and affects individuals over 65. The present study aimed to assess oxidative status relation diet physical activity patients OA. We used a cross-sectional applied 98 females Blood samples were collected determine stress markers: malonyl dialdehyde (MDA), reduced glutathione (GSH), oxidized (GSSG), GSH/GSSG. Diet was estimated standardized food frequency questionnaire. International Physical...
The study aimed to evaluate lifestyle factors among Information Technology (IT) workers from Romania before and during the pandemic. We used an online applied questionnaire, filled in by 1638 respondents, that assessed nutrition status-Body Mass Index (BMI), weight diet change, physical activity, alcohol consumption, number of hours working front computer, stress, sleep. Multivariate logistic regression was establish lead gain. Although level activity (PA) low pandemic, results our showed a...
Genome-wide association studies (GWAS) have successfully revealed numerous susceptibility loci for obesity. The PREDATORR study (2014) shows that in Romania, 346% of adults aged 20–79 y/o are overweight, and 31.4% obese with a high risk cardiometabolic complications, number puts almost 67% Romania’s population the abnormal weight group. Our aims to investigate current status genetic foundation metabolic disease associated obesity, applied pilot group patients specifically examining impact...
OBJECTIVE: Retroflex views of the rectal vault are included in teaching colonoscopic technique but not pervasive clinical practice. The utility adding a retroflex maneuver at end colonoscopy has yet to be determined. aim this study was evaluate additional benefit view completion examination. METHODS: A prospective consecutive colonoscopies performed by single physician conducted. first visually inspected upon withdrawal colonoscope. endoscope then readvanced into rectum and retroflexed...
In recent years, nanoparticles have gained significant importance due to their unique properties, such as pharmacological, electrical, optical, and magnetic abilities, contributing the growth of science technology sector. Particular naturally derived biomolecules with beneficial effects on menopause disorder been subject studies pharmaceutical formulation obtain alternative forms increased bioavailability without side effects, in nanostructured lipid carriers (NLCs) loaded active...
Although many phytochemicals have been used in traditional medicine, there is a great need to refresh the health benefits and adjust shortcomings of herbal medicine. In this research, two principles (Diosgenin Glycyrrhiza glabra extract) coopted Nanostructured Lipid Carriers developed for improving most desirable properties medicine—antioxidant anti-inflammatory actions. The contribution phytochemicals, vegetable oils lipid matrices has highlighted by comparative study size, stability,...
Overt hyperthyroidism (HT) during pregnancy is associated with a risk of maternal–fetal complications. Antithyroid drugs (ATD) have potential for teratogenic effects and fetal–neonatal hypothyroidism. This study evaluated ATD treatment thyroid function control pregnancy, outcome in women HT. Patients methods: A retrospective analysis 36 single fetus pregnancies 29 consecutive (median age 30.3 ± 4.7 years) HT diagnosed before or pregnancy; group 39 healthy euthyroid pregnant was used....