Despite the growing interest in study of Gram-negative bacilli (GNB) infections, very little information on osteomyelitis caused by GNB is available medical literature. : To assess clinical and microbiological features 101 cases alone, between January 2007 2009, a reference center for treatment high complexity traumas city São Paulo. Most patients were men (63%), with median age 42 years, affected chronic (43%) or acute associated to open fractures (32%), majority lower limbs (71%). The...

To evaluate the incidence and microbiological profile of surgical site infections (SSIs) associated with internal fixation fractures to compare differences in SSIs observed among patients closed open fractures.Retrospective study. Analyzed data included information from all who underwent surgery for or January 2005 December 2012 remained outpatients at least one year following surgery. Incidence infection (SSI) was compared between infection, as well polymicrobial related Gram-negative...

Septic arthritis is an infrequent disease although very important due to the possibility of disastrous outcomes if treatment not adequately established. Adequate information concerning epidemiology septic still lacking uncommon nature as well struggle establish a correct case-definition.To epidemiologically characterize population seen at Hospital das Clínicas, University São Paulo with diagnosis between 2006 and 2011.Sixty-one patients diagnosed knee 2011 were retrospectively evaluated. The...

The aim of this study was to estimate the additional cost treatment a group nosocomial infections in tertiary public hospital. A retrospective observational cohort conducted by means analyzing medical records 34 patients with infection after total knee arthroplasty, diagnosed 2006 and 2007, who met criteria for according Centers Disease Control Prevention. To direct costs these patients, following data were gathered: length hospital stay, laboratory tests, imaging examinations, surgical...

Avaliar a incidência e o perfil microbiológico das ISC relacionadas procedimentos de fixação fraturas num hospital acadêmico ortopédico terciário em São Paulo, Brasil, comparar as diferenças observadas entre os pacientes com fechadas expostas. Estudo retrospectivo. Foram incluídos na análise dados relativos todos que passaram por procedimento cirúrgico para ou expostas janeiro 2005 dezembro 2012 mantiveram seguimento pelo menos um ano. Foi verificada presença associação tipo fratura,...

OBJECTIVES:To clinically and epidemiologically characterize a population diagnosed with treated for septic arthritis of the knee, to evaluate treatment results analyze differences between patients positive negative culture results, Gram-positive Gram-negative bacterial isolates S. aureusand non-S.aureus-related infections.METHODS: One hundred five knee were included in this study.The clinical epidemiological data evaluated.Statistical analysis was performed compare without an isolated...

We sought to evaluate the indirect impact of ertapenem use for treatment extended-spectrum beta-lactamase-producing Enterobacteriaceae infections in our hospital on susceptibility Pseudomonas aeruginosa imipenem. The was mandated absence nonfermenting gram-negative bacilli 1 year. imipenem restricted. Imipenem consumption decreased 64.5%. Ertapenem 42.57 defined daily doses per 1,000 patient-days. None 18 P. isolates recovered after introduction were imipenem-resistant, compared with 4 20 previous

INTRODUCTION: Despite the growing interest in study of Gram-negative bacilli (GNB) infections, very little information on osteomyelitis caused by GNB is available medical literature. OBJECTIVES AND METHODS: To assess clinical and microbiological features 101 cases alone, between January 2007 2009, a reference center for treatment high complexity traumas city São Paulo. RESULTS: Most patients were men (63%), with median age 42 years, affected chronic (43%) or acute associated to open...

Treatment of orthopedic infections usually requires prolonged antimicrobial therapy, ranging from 14 days up to 6 months. Nowadays, rising levels resistance demands parenteral therapy for many patients. Outpatient (OPAT) is a modality that allows treatment out hospital in these situations. In Brazil, where public universal healthcare system full coverage all citizens, implantation and dissemination OPAT programs would be beneficial patients the system, because it allow better allocation...

OBJECTIVE:To establish the risk factors for joint infection by oxacillin-resistant Staphylococcus aureus (MRSA) using clinical and epidemiological data.METHODS: All septic arthritis cases of knee hip diagnosed treated in our institution from 2006 to 2012 were evaluated retrospectively.Only patients with cultures identified as microbial agents included study.The characteristics analyzed, seeking differences between populations affected MRSA oxacillin-sensitive (MSSA).RESULTS: S. was isolated...

IOT – Institute of Orthopedics and Traumatology(Instituto de Ortopedia e Traumatologia), Clinical Hospital,School Medicine, Sao Paulo University, started theadministration ertapenem in March 2006. The ClinicalHospital is a tertiary quaternary healthcare center andthe Traumatology isexclusively designed to treat highly complex cases,counting on 200 beds. That antibiotic (ertapenem) wasincluded the standardization use antimicrobialagents intended hospital-acquired infectionsassociated...

Background: Acinetobacter baumannii complex is an increasingly important cause of osteomyelitis. It considered a difficult to treat agent, due increasing antimicrobial resistance and few available therapeutic options. Objective: To compare effectiveness tolerability tigecycline colistin in patients with osteomyelitis caused by carbapenem-resistant A. (CRABC). Methods: This retrospective review included all admitted 150-bed tertiary hospital from 2007 2015 microbiologically confirmed CRABC...

The implantation of joint prostheses, especially for the hip and knee, is becoming increasingly common. This provides a significant reduction in discomfort an immeasurable improvement patient mobility. Reviews worldwide literature indicate that 1 to 5% these prostheses become infected, although it important remember as number operations performed implant prosthesis increases, so will cases this type infection. Gram-positive bacteria predominate contaminations particular Staphylococcus aureus...

Introduction: tuberculosis (TB) remains a major cause of morbidity and mortality worldwide. The incidence TB has increased since the 1980s. Given increasing prevalence worldwide, osteoarticular (OATB) is significant health problem. Methods: retrospective study case series hospitalized patients with confirmed OATB by culture or histopathological examination who were seen at reference orthopedic hospital in São Paulo, Brazil, from 2014 to 2019. Results: thirty bone joint main sites spine (83.3...

Central line-associated bloodstream infections (CLABSIs) are an important type of healthcare-associated infection in intensive care units (ICUs) with high mortality rates and healthcare costs (1). According to the World Health Organization (WHO), CLABSIs also most common cause (2). In United States, median rate ranges from 1.8 5.2 per 1,000 catheter days, according Centers for Disease Control Prevention (CDC) (3). Each year, 100,000 cases 30,000 deaths occur among patients ICUs (4). In...

O aumento considerável da expectativa de vida dos pacientes infectados pelo HIV na era do tratamento antirretroviral alta potência, resulta em importantes alterações metabólicas e osteoarticulares decorrentes prolongado tempo infecção viral desse tratamento. As complicações ortopédicas mais frequentes são as mineralização óssea, a osteonecrose, síndrome túnel carpo capsulite adesiva glenoumeral, com padrão apresentação clínica, evolução natural doença resposta terapêutica diferentes daqueles...

O implante de próteses articulares, principalmente quadril e joelho, vem se tornando cada vez mais frequente, representando significante redução no desconforto imensurável melhora na mobilidade dos pacientes. As revisões da literatura mundial revelam que 1 a 5% destas tornam-se infectadas, sendo importante lembrar que, conforme cresce o número cirurgias para implantação próteses, também casos deste tipo infecção. bactérias gram-positivas são predominantes nas contaminações das em especial...