A5085479221- Skin and Cellular Biology Research
- Dermatological and Skeletal Disorders
- Cutaneous Melanoma Detection and Management
- Genetic and rare skin diseases.
- Cutaneous lymphoproliferative disorders research
- Dermatology and Skin Diseases
- Autoimmune Bullous Skin Diseases
- Acne and Rosacea Treatments and Effects
- Vascular Tumors and Angiosarcomas
- Nonmelanoma Skin Cancer Studies
- Wnt/β-catenin signaling in development and cancer
- Hair Growth and Disorders
- Fungal Infections and Studies
- Vascular Malformations and Hemangiomas
- RNA regulation and disease
- Cell Adhesion Molecules Research
- Immunodeficiency and Autoimmune Disorders
- Urticaria and Related Conditions
- Social Policies and Family
- Tuberous Sclerosis Complex Research
- Cellular Mechanics and Interactions
- Dermatological diseases and infestations
- Body Image and Dysmorphia Studies
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Ubiquitin and proteasome pathways
Ludwig-Maximilians-Universität München
2021-2025
LMU Klinikum
2021-2025
München Klinik
2024
Universitätsmedizin Greifswald
2023
Leoni (Germany)
2023
University Medical Center Freiburg
2019-2022
University of Freiburg
2019-2022
Oxfam
2021
John Wiley & Sons (United States)
2021
Hudson Institute
2021
Background Basal cell carcinoma (BCC) is the most common skin cancer in general population. Treatments vary from Mohs surgery to topical therapy, depending on subtype. Dermoscopy, reflectance confocal microscopy (RCM) and optical coherence tomography (OCT) have gained a foothold daily clinical practice optimize diagnosis subtype-oriented treatment. The new technique of line-field OCT (LC-OCT) allows imaging at high resolution depth, but its use has not yet been investigated larger studies....
Abstract Background The treatment of keratinocyte cancers (KC) strictly depends on their differentiation and invasiveness. Non‐invasive diagnostic techniques can support the diagnosis in real time, avoiding unnecessary biopsies. This study aimed to preliminarily define main imaging criteria histological correlations actinic keratosis (AK), Bowen’s disease (BD) squamous cell carcinoma (SCC) using novel device line‐field confocal optical coherence tomography (LC‐OCT). Methods Dermoscopy LC‐OCT...
Abstract Background Keratinopathic ichthyoses are a group of hereditary skin disorders caused by pathogenic variants in keratin genes such as KRT1 , KRT2 and KRT10 resulting conditions epidermolytic ichthyosis (EI), autosomal‐recessive EI, superficial EI epidermal nevus. Case reports highlight the diversity clinical manifestations, but only limited information exists regarding quality life burden disease. Objectives The objective this study was to assess spectrum, genotype–phenotype...
Abstract Remote consultations are likely to grow in importance the following years, especially if coronavirus disease 2019 (COVID‐19) pandemic continues. Patients’ opinions on teledermatology have already been analyzed, but a current analysis during COVID‐19 is lacking. The purpose of this survey was investigate satisfaction patients who had received dermatological advice via telephone and analyze their general opinion about eHealth as well possible limitations for broad implementation....
Background: Allergic diseases represent a major global health issue with more than one-third of the population affected by at least one allergic condition. conditions can not only cause life-threatening anaphylactic reactions but also impact daily life significant influence on mental and quality (QoL). Objectives: This study aims to evaluate health-related QoL depression severity among patients presenting in tertiary care allergy center. Methods: A cross-sectional was conducted 596 symptoms...
Abstract Background Short anagen hair (SAH) is a rare paediatric disorder characterized by short phase, an inability to grow long scalp and negative psychological impact. The genetic basis of SAH currently unknown. Objectives To perform molecular investigations in 48 individuals with clinical phenotype suggestive identify, if any, the this condition. Methods Exome sequencing was performed 27 patients diagnosed or complaint short, nongrowing hair. cohort screened for variants minor allele...
In this survey, we analyzed data from patients suffering the most common cutaneous T-cell lymphomas (CTCLs) subtypes mycosis fungoides (MF) and Sézary syndrome (SS), treated with retinoid alitretinoin during a 7-year period at our outpatient department between 2015 2020.We patient medical records including TNMB stage, side effects under therapy alitretinoin, time to next treatment (TTNT), previous photo documentation.A total of 35 MF (n = 28) SS 7) were included in study, whom 69% male 31%...
Demodex spp. mites are the most complex resident of human skin microbiome. Although they considered commensals, can be pathophysiologically relevant in inflammatory diseases like rosacea. Until now, there is no culture system available for these except using live vertebrate hosts.Our aim was to establish an ex vivo and characterize sebogenesis-dependent mite density.Demodex were cultivated pilosebaceous units explants, called organotypic explant (hOSEC). Furthermore, different...
Abstract While the incidence of infections with human immunodeficiency virus largely remained unchanged in Germany, an increase other sexually transmitted (STIs) was observed. The aim to analyse effectiveness our sexual education lecture for students improving awareness, knowledge and prevention STIs. We conducted a cross-sectional survey after had attended extra-curricular at Department Dermatology Ludwig-Maximilians-University Munich, Germany (LMU). compared data previously performed study...
Non-syndromic congenital ichthyosis describes a heterogeneous group of hereditary skin disorders associated with erythroderma and scaling at birth. Although both severe mild courses are known, the prediction natural history in clinical practice may be challenging.To determine course genotype-phenotype correlations children affected by non-syndromic case series from south-western Germany.We performed retrospective observational study 32 ichthyoses seen our genodermatosis clinic between 2011...
The corona pandemic affects many aspects of life - with challenges in medical treatment undoubtedly paramount importance. However, continuing education needs to be consistently provided. During a semester lockdown-phases and limited student-to-patient-contact availability, we supplied silicone models primary skin lesions every student asked them evaluate this teaching tool.In two anonymous online surveys, students enrolled dermatology (n = 222) at the Medical Facility Ludwig Maximilian...
Introduction: The coronavirus pandemic forced universities to transfer academic curricula into the digital realm and calls for introduction of new teaching methods adequately compensate limited in-patient training. Especially in field dermatology, use 3D models presents an interesting opportunity maintain diagnostically essential sensory haptic characteristics primary lesions. Objectives: We developed a prototype silicone model presented it medical service Department Dermatology...
Zusammenfassung Hintergrund und Ziele: Die Corona‐Pandemie betrifft eine Fülle von verschiedenen Lebensaspekten – Herausforderungen in der medizinischen Behandlung sind hier unzweifelhaft höchster Wichtigkeit. Allerdings muss auch, um die Ausbildung Studierenden zu gewährleisten, fortlaufende medizinische Lehre stattfinden. Während eines Semesters mit Lockdown‐Phasen eingeschränktem Patientenkontakt für schickten wir jedem ein Silikonmodell baten Evaluation dieses Lernwerkzeugs. Methoden:...
Autosomal recessive epidermolytic ichthyosis is a rare skin condition associated with KRT10 loss-of-function mutations. It presents severe life-threatening clinical manifestations. Here we describe case of autosomal an unusually mild, spontaneously improving phenotype. Erythroderma and superficial blistering were present at birth, but the recovered remained almost intact age 1 year. Mild scaling on neck fragility manifesting as erosions after scratching only features child grew. As cause,...
Background Allergic diseases represent a major global health issue with more than one third of the population affected at least allergic condition. conditions can not only cause life threatening anaphylactic reactions but also impact on daily significant influence mental and quality (QoL) Objectives This study aims to evaluate related QoL depression severity among patients presenting in tertiary care allergy center. Methods A cross-sectional was conducted 628 symptoms or previously diagnosed...
Inborn errors of immunity (IEI) can affect different parts the immune system and manifest especially through pathological infection susceptibility dysregulation. Cutaneous manifestations IEI hint at underlying immunodeficiency tendency for inflammation. These present as recurring eczema, erythema, abscesses, hair loss with poor response to therapy. be specific certain IEI, or rather unspecific. Together clinical course severity, they indicate diagnosis. Early accurate recognition, diagnosis,...