A5107940240- Glioma Diagnosis and Treatment
- Head and Neck Cancer Studies
- Ferroptosis and cancer prognosis
- Radiomics and Machine Learning in Medical Imaging
- Head and Neck Surgical Oncology
- Immune cells in cancer
- Salivary Gland Tumors Diagnosis and Treatment
- Brain Metastases and Treatment
- Cancer-related molecular mechanisms research
- Lung Cancer Research Studies
- Cancer Immunotherapy and Biomarkers
- Cancer Diagnosis and Treatment
- Colorectal Cancer Surgical Treatments
- Medical Imaging and Pathology Studies
- MRI in cancer diagnosis
- Circular RNAs in diseases
- Occupational and environmental lung diseases
- Pleural and Pulmonary Diseases
- Inflammasome and immune disorders
- Effects of Radiation Exposure
- Remote Sensing in Agriculture
- Food Chemistry and Fat Analysis
- Cancer-related cognitive impairment studies
- Vehicle Routing Optimization Methods
- Optimism, Hope, and Well-being
First Affiliated Hospital of Fujian Medical University
2016-2025
Fujian Medical University
2016-2025
Ministry of Agriculture and Rural Affairs
2024-2025
Guangdong Academy of Agricultural Sciences
2024-2025
Jinan University
2024
First Affiliated Hospital of Xi'an Jiaotong University
2024
China Meteorological Administration
2024
Beijing Meteorological Bureau
2024
Ocean University of China
2024
University of Shanghai for Science and Technology
2024
Objective: Despite several clinicopathological factors being integrated as prognostic biomarkers, the individual variants and risk stratification have not been fully elucidated in lower grade glioma (LGG). With prevalence of gene expression profiling LGG, based on critical role immune microenvironment, aim our study was to develop an immune-related signature for prognosis prediction LGG. Methods: RNA-sequencing data from The Cancer Genome Atlas (TCGA), Tissue Expression (GTEx), Chinese...
The purpose of this study was to evaluate the 7th edition UICC/AJCC staging system for nasopharyngeal carcinoma (NPC) patients who were treated with intensity modulated radiation therapy (IMRT).The clinical data 1241 NPC initial magnetic resonance imaging (MRI) scans studied retrospectively. All MRIs independently reevaluated and restaged according by two radiologists specializing in head neck cancers. Analysis prognostic factors local relapse-free survival (LRFS), distant metastasis-free...
As a prevalent and infiltrative cancer type of the central nervous system, prognosis lower-grade glioma (LGG) in adults is highly heterogeneous. Recent evidence has demonstrated prognostic value mRNA expression-based stemness index (mRNAsi) LGG. Our aim was to develop index-based signature (SI-signature) for risk stratification survival prediction.Differentially expressed genes (DEGs) between LGG Cancer Genome Atlas (TCGA) normal brain tissue samples from Genotype-Tissue Expression (GTEx)...
Abstract Background Tumor-associated neutrophils (TANs) in the tumor microenvironment are prognostic biomarkers many malignancies. However, it is unclear whether TANs can serve as a marker for clinical outcomes patients with glioblastoma (GBM), classified according to World Health Organization Classification of Tumors Central Nervous System, fifth edition (CNS5). In present study, we analyzed correlations and peripheral blood prior radiotherapy overall survival (OS) GBM Methods RNA-seq...
ABSTRACT Objective Several observational studies have identified an association between plasma proteins and hepatocellular carcinoma (HCC). This study aimed to explore the potential causal relationship circulating protein‐to‐protein ratio morbidity risk of HCC. Methods Genetic data for 2821 ratios were sourced from UKB PPP Suhre's study. HCC FinnGen cohort (finngen‐R11‐HCC) IEU OpenGWAS project (ieu‐b‐4953). Subsequently, a two‐sample Mendelian randomization (MR) drug‐targeted MR approach...
Abstract Parotid area lymph node ( PLN ) metastasis in nasopharyngeal carcinoma NPC is rare, and its prognosis remains largely unknown. Our study aimed to investigate the prognostic value staging categories of patients with treated intensity‐modulated radiation therapy IMRT ), provide a reference for clinical treatment metastasis. Records 1616 untreated without distant was retrospectively reviewed. All underwent magnetic resonance imaging MRI examination prior then received as their primary...
Benefit of percutaneous endoscopic gastrostomy in patients undergoing definitive chemoradiotherapy for locally advanced nasopharyngeal carcinoma Yun Xu,1,2 Qiaojuan Guo,1,2 Jin Lin,1,2 Bijuan Chen,1,2 Jiangmei Wen,1,2 Tianzhu Lu,1,2 Yuanji Mingwei Zhang,1,2 Jianji Pan,1,2 Shaojun Lin1,2 1Department Radiation Oncology, Fujian Provincial Cancer Hospital, 2Fujian Key Laboratory Translational Medicine, Fuzhou, Fujian, People’s Republic China Background and aim: To evaluate the impact (PEG)...
This study aims to explore the applicability of Nutrition Risk Screening 2002 (NRS2002) tool in screening nutritional risk and Patient-Generated Subjective Global Assessment (PG-SGA) determining nutrition status nasopharyngeal carcinoma (NPC) patients.NRS2002 PG-SGA were simultaneously applied evaluate NPC patients before induction chemotherapy, as well after radiotherapy. The results considered golden standard evaluating status, ROC curve value Youden index analyze NRS2002 effectiveness...
Major depressive disorder (MDD) is a severe disease characterized by multiple pathological changes. However, there are no reliable diagnostic biomarkers for MDD. The aim of the current study was to investigate gene network and underlying pathophysiology MDD.In this study, we conducted comprehensive analysis mRNA expression profile MDD using data from Gene Expression Omnibus (GEO). dataset (GSE98793) with 128 64 control whole blood samples divided randomly into two non-overlapping groups...
Glioblastoma multiform is a lethal primary brain tumor derived from astrocytic, with poor prognosis in adults. Reticulocalbin-1 (RCN1) calcium-binding protein, dysregulation of which contributes to tumorigenesis and progression various cancers. The present study aimed identify the impact RCN1 on outcomes patients multiforme (GBM). applied two public databases require RNA sequencing data samples clinical for construction training set validation set, respectively. We used bioinformatic...
The optimal approach to assess the postoperative status of lymph nodes in differentiated thyroid cancer (DTC) remains controversial. Our aim was determine if log odds negative nodes/T stage ratio (LONT) could serve as a new prognostic and predictive tool for DTC without metastases patients aged ≥ 55 years.The Surveillance, Epidemiology, End Results (SEER) database used study role LONT ≥55 years diagnosed with metastases. primary outcome overall survival (OS). Kaplan-Meier method Cox...