A5100608692- Climate Change and Health Impacts
- Air Quality and Health Impacts
- Folate and B Vitamins Research
- Liver Disease Diagnosis and Treatment
- Thermoregulation and physiological responses
- Global Health Care Issues
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiovascular Health and Disease Prevention
- Cancer, Lipids, and Metabolism
- Nutritional Studies and Diet
- Immune Response and Inflammation
- Influenza Virus Research Studies
- Health disparities and outcomes
- Retinoids in leukemia and cellular processes
- Lipoproteins and Cardiovascular Health
- Asthma and respiratory diseases
- Maritime Transport Emissions and Efficiency
- Diabetic Foot Ulcer Assessment and Management
- Cerebrovascular and Carotid Artery Diseases
- Vitamin D Research Studies
- COVID-19 Clinical Research Studies
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Urticaria and Related Conditions
- Healthcare Systems and Technology
Chongqing University of Posts and Telecommunications
2025
Tongmyong University
2024-2025
Beijing Center for Disease Prevention and Control
2025
Tianjin Metallurgical Vocational Technical College
2024
Kunming Medical University
2024
Yan'an Hospital Affiliated To Kunming Medical University
2024
Nanchang University
2017-2023
Peking Union Medical College Hospital
2018-2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2018-2023
First Affiliated Hospital of Nanchang University
2023
<h3>Importance</h3> Uncertainty remains about the efficacy of folic acid therapy for primary prevention stroke because limited and inconsistent data. <h3>Objective</h3> To test hypothesis that with enalapril is more effective in reducing first than alone among Chinese adults hypertension. <h3>Design, Setting, Participants</h3> The China Stroke Primary Prevention Trial, a randomized, double-blind clinical trial conducted from May 19, 2008, to August 24, 2013, 32 communities Jiangsu Anhui...
Background and Purpose— Elevated blood homocysteine concentration increases the risk of stroke, especially among hypertensive individuals. Homocysteine is largely affected by methylenetetrahydrofolate reductase C677T polymorphism folate status. Among patients, we aimed to test hypothesis that association between stroke can be modified folic acid intervention. Methods— We analyzed data 20 424 adults enrolled in China Stroke Primary Prevention Trial. The participants, first stratified...
Abstract Background Studies on the associations between ambient temperature and asthma hospitalizations are limited, results controversial. We aimed to assess short-term effects of risk quantify hospitalization burdens attributable non-optimal in adults Beijing, China. Methods collected daily hospitalizations, meteorological factors air quality data Beijing from 2012 2015. applied a time-stratified case-crossover design fitted distributed lag non-linear model with conditional quasi-Poisson...
We sought to determine whether folic acid supplementation can independently reduce the risk of first stroke associated with elevated total cholesterol levels in a subanalysis using data from CSPPT (China Stroke Primary Prevention Trial), double-blind, randomized controlled trial.A 20 702 hypertensive adults without history major cardiovascular disease were randomly assigned double-blind daily treatment an enalapril 10-mg and 0.8-mg tablet or alone. The primary outcome was stroke.The median...
Natural borneol (NB, called “Bingpian”) is an important traditional Chinese medicine to restore consciousness, remove heat and relieve pain, all of which are inflammation-related diseases. Recently, due the limited source NB, synthetic (SB) widely used as a substitute for NB in clinics. However, little known about effects SB instead NB. Herein, aim present study was compare on chemical profiles by gas chromatography-mass spectrometer (GC-MS) analysis, anti-inflammatory activity...
Membrane protein immobilization is particularly significant in vitro drug screening and determining drug-receptor interactions. However, there are still some problems the of membrane proteins with controllable direction high conformational stability, activity, specificity. Cell chromatography (CMC) retains complete biological structure proteins. conventional CMC has limitation poor which results its limited life span low reproducibility. To overcome this limitation, we propose a method for...
Diabetic foot ulcer (DFU) is a common and serious complication of diabetes, its treatment challenging. Platelet-rich plasma (PRP) gel umbilical cord mesenchymal stem cells (UC-MSCs) have been concerned as new therapies for DFU in recent years, comparative studies on the efficacy mechanisms these methods, however, are rarely reported.
Over the past few decades, a growing body of epidemiological studies found effects temperature on cardiovascular disease, including risk for acute myocardial infarction (AMI). Our study aimed to investigate whether there is an association between extremely and hospital admission in Beijng, China. We obtained 81029 AMI cases daily data from January 1, 2013 December 31, 2016. employed time series design modeled distributed lag nonlinear model (DLNM) analyze cases. Compared with 10th percentile...
The aim of the present post hoc analysis China Stroke Primary Prevention Trial (CSPPT) was to evaluate effect folic acid supplementation on risk new-onset diabetes in hypertensive adults China.In all, 20 702 with no history stroke and/or myocardial infarction (MI) were randomly assigned receive double-blind daily treatment tablets containing either: (i) 10 mg enalapril and 0.8 (n = 348); or (ii) alone 354). New-onset defined as either self-reported physician-diagnosed use glucose-lowering...
Abstract Background Atrial fibrillation (AF) is an important arrhythmia associated with cardiovascular morbidity and mortality. This study focused on exploring the potential relationship between short‐term air pollution exposure occurrence of AF. Methods A case‐crossover design was used to investigate effect pollutants AF among 100 patients from 2013 2014. The included ambient particulate matter less than 2.5 μm in aerodynamic diameter (PM ), 10 nitrogen dioxide (NO 2 sulfur (SO carbon...
To evaluate the effects of co-administration inactivated avian influenza H5N1 virus (IAIV) and different Toll-like receptor (TLR) ligands in chickens, 10-d-old chickens were immunized intranasally with IAIV TLR ligand [Bacillus subtilis spores, polyinosinic-polycytidylic acid, CpG oligodeoxynucleotides (CpG-ODN), respectively]. The results showed that both anti-avian (AIV) specific secretory IgA level respiratory tract anti-AIV IgG serum significantly increased, as well expressions IL-12,...
Saposhnikoviae Radix, the dried root of divaricata, is commonly used in traditional Chinese anti-allergic preparations, like Bofutsusho-san and Yupingfeng granules. A high-expression Mas-related G protein-coupled receptor X2 cell membrane chromatography coupled online with high-performance liquid combined an ion trap time-of-flight multistage mass spectrometry system was established for screening identifying components Radix. The validated excellent specificity suitability using appropriate...
The study of volatile organic compounds (VOCs) in exhaled breath presents significant potential for noninvasive disease diagnosis and human exposure monitoring. While thermal desorption (TD) tubes are the most commonly used preconcentration technique analyzing VOCs breath, they still face practical challenges, mainly selective adsorption interference from water vapor samples. This is first to develop a method combining Stirling cooling technology with gas chromatography-flame ionization...
Purpose: To evaluate the associations between acute exacerbations of chronic obstructive pulmonary disease (AECOPD) hospitalizations and daily mean temperature (Tmean) as well apparent (AT), to explore practical values these two indices in policymaking patient education. Methods: Daily AECOPD Meteorological data Beijing were obtained 2013 2016. Distributed lag non-linear model was adopted investigate association ambient hospitalizations. The cumulative effects cold/hot abstracted. For...
Objectives Our work aimed at exploring the relationship between cold spells and acute exacerbation of chronic obstructive pulmonary disease (AECOPD) hospitalisations in Beijing, China, assessing moderating effects intensities durations spells, as well identifying vulnerable. Design A time-series study. Setting We obtained data AECOPD hospitalisations, meteorological variables air quality index China during 2012–2016. Participants All among permanent residents seasons (November–March)...