A5006307377- Glioma Diagnosis and Treatment
- Meningioma and schwannoma management
- Neurofibromatosis and Schwannoma Cases
- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Vascular Malformations Diagnosis and Treatment
- Infectious Diseases and Tuberculosis
- Traumatic Brain Injury and Neurovascular Disturbances
- Musculoskeletal pain and rehabilitation
- Sarcoma Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Intracranial Aneurysms: Treatment and Complications
- Fetal and Pediatric Neurological Disorders
- Spinal Hematomas and Complications
- Pituitary Gland Disorders and Treatments
- Bacterial Infections and Vaccines
- Cerebrospinal fluid and hydrocephalus
- Cerebral Venous Sinus Thrombosis
- Trauma Management and Diagnosis
- Radiomics and Machine Learning in Medical Imaging
- Biochemical Acid Research Studies
- Traumatic Ocular and Foreign Body Injuries
- Vascular Procedures and Complications
- Case Reports on Hematomas
- Head and Neck Surgical Oncology
Education Training And Research
2025
Universidad CES
2024-2025
Istanbul University
2018-2024
Fatih Sultan Mehmet Eğitim Ve Araştırma Hastanesi
2019-2024
Sağlık Bilimleri Üniversitesi
2022-2024
Okan University
2016-2019
Bahçeşehir University
2019
Acıbadem Kadıköy Hospital
2008-2017
Istanbul Memorial Hospital
2016
Memorial Sisli Hospital
2016
Traumatic brain injury (TBI) was induced by a weight-drop device using 300 g-1 m weight-height impact. The study groups were: control, alpha-lipoic acid (LA) (100 mg/kg, po), TBI, and TBI + LA po). Forty-eight hours after the injury, neurological scores were measured samples taken for histological examination or determination of thiobarbituric reactive substances (TBARS) glutathione (GSH) levels, myeloperoxidase (MPO) Na(+)-K(+) ATPase activities, whereas cytokines (TNF-alpha, IL-1beta)...
The aim of this retrospective study was to investigate the diagnostic yield and accuracy stereotactic biopsy in patients harboring brain mass. Stereotactic performed 130 between 1995 2000 an educational research hospital Turkey. results histological analysis were compared resected specimens 23 patients. lesions lobar 62% cases deep‐seated 38% cases. During procedures, pathologist operating theatre a very small fragment used for cytological examination. No frozen section any Samples 122...
Background: Nosocomial meningitis is a rare complication following neurosurgical procedures and associated with high morbidity mortality. Aim: The aim of this study was to describe the clinical characteristics risk factors mortality in patients who developed nosocomial operations. Setting design: Tertiary care hospital an observational study. Materials Methods: subjects included 2265 underwent various operations during 2003-05. diagnosis based on Center for Disease Control criteria....
The overproduction of reactive oxygen species and resultant damage to cellular proteins or lipids cell membranes DNA by free radicals are the underlying mechanisms many neuropathologies. Cyclooxygenase-2 (COX-2) inhibitors have been suggested be neuroprotective reducing prostanoid radical synthesis, directing arachidonic acid metabolism through alternate pathways. This study investigated putative effect COX-2 inhibitor, meloxicam, in a rat model diffuse brain injury.Sprague-Dawley rats were...
Oxidative stress is a mediator of secondary injury to the spinal cord following trauma.To investigate putative neuroprotective effect alpha-lipoic acid (LA), powerful antioxidant, in rat model (SCI).Wistar albino rats were divided as control, vehicle-treated SCI, and LA-treated SCI groups. To induce standard weight-drop method that induced moderately severe (100 g/cm force) at T10 was used. Injured animals given either 50 mg/kg LA or saline 30 minutes postinjury by intraperitoneal injection....
Introduction: Traumatic brain injury is highly associated with the over-production of reactive oxygen species. The aim this study was to investigate putative neuroprotective effect montelukast, a cysteinyl-leukotriene receptor antagonist, in rat model traumatic (TBI).Methods: Sprague Dawley rats were subjected TBI weight-drop device using 300 g-1 m weight-height impact. groups were: control (saline), montelukast (10 mg kg −1 per day, ip), trauma and + montelukast. Two days post-trauma,...
Ozone (O 3 ) is a gas that contains three atoms of oxygen with cyclic structure (5).It induces antioxidant stress and promotes resistance against oxidative (13,15) has been used as an agent in inflammation (26).Oxygen-ozone therapy known to be bio-oxidative procedure (2) application low-dose ozone inhibits prostaglandin synthesis, release bradykinin algogenic substances, proteinase secretion from macrophages polymorphonuclear leukocytes (8).█ INTRODUCTION C erebral vasospasm one the main...
Screw-loosening is a common instrumentation-related complication following fusion. Patients who present with pain and neurological symptoms due to screw-loosening require revision. It has been reported that fat-infiltrated and/or atrophied paraspinal muscles were associated low back pain, disability, radiculopathy, failures. However, there limited conflicting knowledge regarding the association of screw-loosening. In study, we aimed identify whether fatty infiltration in was A retrospective...
Traumatic injury to the central nervous system results in delayed dysfunction and neuronal death. Impaired mitochondrial function, generation of reactive oxygen species (ROS), lipid peroxidation occur soon after traumatic spinal cord (SCI), while activation compensatory molecules that neutralize ROS occurs at later time points. The aim current study was investigate putative neuroprotective effect COX2 inhibitor meloxicam a rat model SCI. In order induce SCI, standard weight-drop method...
Despite low back pain being common in pregnancy, cauda equina syndrome is rare. Misdiagnosis and delay treatment may cause neurological sequelae including urinary fecal incontinence, sexual dysfunction patients. A case of a pregnant woman at 25-week gestation presented here. The patient underwent an emergency, standard lumbar microdiscectomy under general anesthesia on prone position. Neither the nor baby had any complication related to surgery.
Brown tumor (BT), also known as osteoclastoma, may appear in the context of primary and secondary hyperparathyroidism. Spinal cord compression due to BT is extremely rare. We present here an unusual case involving thoracal spine mandible. A 26-year-old woman, who had been on hemodialysis for chronic renal failure over 6 years, got admitted with dorsal pain progressive weakness her lower extremities gait disturbances. Neurological examination revealed spastic paraparesis symmetrically...
Pseudoaneurysms of the superficial temporal artery are mostly traumatic in origin.Here, a case aneurysm that emerged following recraniotomy is presented.A 59-year-old woman was admitted with subarachnoid hemorrhage.She underwent pterional craniotomy and clipping saccular middle cerebral bifurcation.A control digital subtraction angiography on 3rd postoperative day revealed partial filling revision performed.The second 4th showed pseudoaneurysm left artery.The excised successfully under local...
To investigate the vascular variations in patients with intracranial aneurysm circle of Willis.We used data on 128 consecutive cases. Cerebral angiography images were analyzed retrospectively. Arteries grouped as anterior cerebral arterial system (ACS), posterior (PCS) and middle (MCS) for grouping variations. Lateralization, being single/multiple, gender; also any connection accompanying aneurysms" number, localization, dimension, whether bleeding/incidental has been inspected.Variations...
adequate therapy (34).Stereotactic surgery started with the Horsley-Clarke apparatus in 1908 ( 14).After introduction of stereotactic human patients by Spiegel and Wycis 1947, this approach has been used safely effectively to obtain tissue diagnosis for intracranial lesions.There are many papers establishing issues related safety, accuracy diagnostic yield biopsy literature (6,9,10,24,28,31,34).█ INTRODUCTION E xact histological diagnoses still important strongly recommended when deciding on...
Despite many reports investigating the relationship of subarachnoid haemorrhage and seasonal variation in different parts world, there is no clear correlation. As far as we know this subject has not been reported from Istanbul yet. The purpose study to determine if any correlation between season spontaneous (SAH) caused by intracranial aneurysms and/or arteriovenous malformations (AVM) Istanbul.Data were collected retrospectively medical patients having due aneurysm malformation. data...