- Burn Injury Management and Outcomes
- Trauma and Emergency Care Studies
- Injury Epidemiology and Prevention
- Cardiac, Anesthesia and Surgical Outcomes
- Wound Healing and Treatments
- Lung Cancer Diagnosis and Treatment
- Hernia repair and management
- Disaster Response and Management
- Gastric Cancer Management and Outcomes
- Pelvic and Acetabular Injuries
- Cancer, Hypoxia, and Metabolism
- Venous Thromboembolism Diagnosis and Management
- Cardiac Arrest and Resuscitation
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Abdominal Trauma and Injuries
- Congenital Diaphragmatic Hernia Studies
- Vascular Procedures and Complications
- Appendicitis Diagnosis and Management
- Medical Malpractice and Liability Issues
- Immune Cell Function and Interaction
- Angiogenesis and VEGF in Cancer
- Climate Change and Health Impacts
- Hepatocellular Carcinoma Treatment and Prognosis
- Cardiac Valve Diseases and Treatments
- Trauma Management and Diagnosis
Loyola University Medical Center
2021-2025
Loyola University Chicago
2023-2025
Loyola Medicine
2022-2024
Brigham and Women's Hospital
2020-2022
University of Washington
2022
Harvard University
2022
University of Portland
2022
The University of Texas Southwestern Medical Center
2018-2022
The University of Texas Medical Branch at Galveston
2022
University of Maryland, Baltimore
2021
This Clinical Practice Guideline (CPG) addresses the topic of acute fluid resuscitation during first 48 hours following a burn injury for adults with burns ≥20% total body surface area (%TBSA). The listed authors formed an investigation panel and developed clinically relevant PICO (Population, Intervention, Comparator, Outcome) questions. A systematic literature search returned 5978 titles related to this after 3 levels screening, 24 studies met criteria address questions were critically...
Despite the widespread institution of modern massive transfusion protocols with balanced blood product ratios, survival for patients traumatic hemorrhage receiving ultramassive (UMT) (defined as ≥20 U packed red cells [RBCs]) in 24 hours) remains low and resource consumption high. Therefore, we aimed to identify factors associated mortality trauma UMT resuscitation era.An Eastern Association Surgery Trauma multicenter retrospective study 461 from 17 centers who received RBCs hours was...
Trauma patients have an increased risk of venous thromboembolism (VTE), partly because greater inflammation. However, it is unknown if this association present in who undergo emergency general surgery (EGS).To investigate whether case status independently associated with VTE compared elective and to test the hypothesis that cases would a higher VTE.This retrospective cohort study used American College Surgeons National Surgical Quality Improvement Program database from January 1, 2005,...
Abstract Burn shock and acute fluid resuscitation continue to spark intense interest debate among burn clinicians. Following a major injury, of is life-saving, but paradoxically can also be source increased morbidity mortality because the unintended consequence systemic edema formation. Considerable research over past two decades has been devoted understanding mechanisms formation, develop strategies curb fluids limit development. Recognition endotheliopathy—injury endothelium’s glycocalyx...
It is well known that liver disease has an adverse effect on postoperative outcomes. However, what still unknown how to appropriately risk stratify this patient population based the degree of failure. Because data are limited, specifically in general surgery practice, we analyzed model end-stage (MELD) terms predicting complications after one three operations: inguinal hernia repair (IHR), umbilical (UHR), and colon resection (CRXN). National Surgical Quality Improvement Program 17,812 total...
Abstract Introduction Large burns induce a systemic inflammatory response, compromising vascular endothelium and hemodynamics, resulting in the degradation of endothelial glycocalyx (EG), luminal barrier regulating passage molecules. EG breakdown releases Angiopoietin (Ang)-1 Ang-2, essential mediators integrity peripheral tissues within bone marrow by competing for TIE2 receptor. Ang-2 acts to increase permeability. potentially worsening capillary leak, tissue edema, hypoxia. We propose...
Abstract Introduction Inhalation injury greatly contributes to the morbidity and mortality of burn patients. With limited treatment options for inhalation injury, patients are at an increased risk developing secondary respiratory complications, such as pneumonia (PNA). The impact complications on course stay with remains poorly described. This study aims assess association between PNA, developed in setting hospital outcomes. Methods utilized American Burn Association Care Quality Platform...
Abstract Introduction Inhalation injury is present in 10-20% of all burn admissions. Clinical diagnosis, triage, and prognostication remains difficult with poor accuracy given the heterogeneity patterns. In setting a mass casualty incident, ability to accurately diagnosis inhalation critical triage resource allocation for patients injury. As such we sought test feasibility using handheld ultrasound detect smoke lung (SILI) inhalation. Methods An observational survey study was conducted....
A consensus on the optimal surgical approach for repair of a paraesophageal hernia has not been reached. The aim this study was to examine outcomes open and laparoscopic repairs (PHR), both with without mesh. review National Surgical Quality Improvement Program (NSQIP) database from 2007 2011 conducted. Patients who underwent an or PHR were included. primary outcome 30-day mortality. Secondary included infections, respiratory cardiac complications, intraoperative perioperative transfusions,...
Patient Safety Indicators (PSIs) were originally intended for use as a screen quality of care but are now being used to rank hospitals and modify hospital reimbursement. PSI data dependent on accuracy clinical documentation coding. Information whether event is inherent the nature operation or posed significant impact outcome lacking. Cases one year at single academic center queried. with target PSIs included (n = 136). evaluated both significance injury. Both patient safety officers agreed...
Abstract On June 17 to 18, 2019, the American Burn Association, in conjunction with Underwriters Laboratories, convened a group of experts on burn resuscitation Washington, DC. The goal meeting was identify and discuss novel research strategies optimize process resuscitation. Patients who sustain large thermal injury (involving >20% total body surface area [TBSA]) face sequence challenges, beginning shock. Over last century, has helped elucidate much underlying pathophysiology shock,...
Background and Objectives:The advantages of laparoscopy over open surgery are well established. Laparoscopic resection for gastric cancer is safe results in equivalent oncologic outcomes when compared with resection. The purpose this study was to assess the use treat associated outcomes.Methods:The American College Surgeons National Surgical Quality Improvement Project (NSQIP) dataset queried patients (ICD-9 Code 151.0–151.9) from January 2005 through December 2012. Logistic regression used...