A5035553382- Vibrio bacteria research studies
- Salmonella and Campylobacter epidemiology
- Fecal contamination and water quality
- Child Nutrition and Water Access
- Viral gastroenteritis research and epidemiology
- Antibiotic Resistance in Bacteria
- Parasitic Infections and Diagnostics
- Amoebic Infections and Treatments
- Congenital Anomalies and Fetal Surgery
- Parasitic infections in humans and animals
- Antibiotic Use and Resistance
- Parasite Biology and Host Interactions
Kenya Medical Research Institute
2021-2025
Children who have been discharged from hospital in sub-Saharan Africa remain at substantial risk of mortality the post-discharge period. Antimicrobial resistance (AMR) may be an important factor. We sought to determine prevalence and factors associated with AMR commensal Escherichia coli (E. coli) Kenyan children time discharge.Fecal samples were collected 406 aged 1-59 months western Kenya discharge cultured for E. coli. Susceptibility ampicillin, ceftriaxone, cefotaxime, ceftazidime,...
Non-typhoidal Salmonella (NTS) presents a considerable health threat to children in low-resource settings, where clean water, sanitation, and hygiene are often inadequate. However, the environmental factors influencing NTS persistence spread remain poorly understood. We utilized case-control approach investigate associated with infection living Nairobi’s informal settlements between August 2022 July 2023. Stool samples were collected from febrile children, or without diarrhea, who visited...
Typhoid fever cases and carriers can transmit Salmonella enterica serovar Typhi ( S . Typhi) through fecal shedding. It remains unclear whether the shedding by exhibits similar phenotypic genotypic characteristics to those from acute cases. We investigated multidrug resistance in individuals residing urban informal settlements Nairobi, Kenya. recruited participants ≤ 65 years six health facilities tested for typhoid infection blood stool cultures. The culture-positive were treated followed...
Abstract Cholera is a diarrhoeal disease caused by the toxigenic Vibrio cholerae ( V. ) bacterium. can contaminate drinking water sources and food through poor sanitation hygiene, especially in informal settlements refugee camps where cholera outbreaks have been reported Kenya. This study aimed to identify environmental transmission routes of within Mukuru settlement Nairobi. We collected nine types samples (drinking water, flood open drains, surface shaved ice, raw produce, street food,...
Dogs living in a domestic-wildlife interface can serve as reservoirs and sentinels of parasites shared among humans, domestic animals wildlife. In Kenya, the epidemiology intestinal dogs their role zoonoses is poorly understood, especially interfaces. This study aimed to determine occurrence helminths Oloisukut Conservancy. One hundred dog faecal samples were collected per rectum examined microscopically following zinc chloride flotation formal-ether concentration techniques. Genotyping was...
Nontyphoidal
The causative agent of typhoid fever,
Cholera is a diarrhoeal disease caused by Vibrio cholerae (V. cholerae) bacterium, with strains belonging to serogroups 01 and 0139 causing huge proportion of the disease. V. can contaminate drinking water sources food through poor sanitation hygiene. This study aimed identify environmental routes exposure within Mukuru informal settlement in Nairobi. We collected nine types samples (drinking water, flood open drains, surface shaved ice, raw produce, street food, soil, public latrine swabs)...
Although typhoid fever has largely been eliminated in high-income countries, it remains a major global public health concern especially among low- and middle-income countries. The causative agent, Salmonella enterica serovar Typhi ( S. Typhi), is human restricted pathogen with limited capacity to replicate outside the host. Human carriers, 90% of whom have gallstones their gallbladder, continue shed for an ill-defined period time after treatment. genetic mechanisms involved establishing...