Arthur W. Toga
A5102799042- Advanced Neuroimaging Techniques and Applications
- Functional Brain Connectivity Studies
- Advanced MRI Techniques and Applications
- Fetal and Pediatric Neurological Disorders
- Traumatic Brain Injury Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Dementia and Cognitive Impairment Research
- MRI in cancer diagnosis
- Medical Image Segmentation Techniques
- Alzheimer's disease research and treatments
- Tensor decomposition and applications
- Trauma and Emergency Care Studies
- Bone and Joint Diseases
- Cardiac Arrest and Resuscitation
- Cerebrovascular and Carotid Artery Diseases
- Cerebrospinal fluid and hydrocephalus
- Amyotrophic Lateral Sclerosis Research
- Parkinson's Disease Mechanisms and Treatments
- Scientific Computing and Data Management
- Morphological variations and asymmetry
- Biomedical Text Mining and Ontologies
- Schizophrenia research and treatment
- Cell Image Analysis Techniques
- Medical Imaging Techniques and Applications
- Health, Environment, Cognitive Aging
University of Southern California
2016-2025
Neurological Surgery
2015-2021
Oxford University Press (United Kingdom)
2020
Cognitive Neuroimaging Lab
2018
University of California, Los Angeles
2004-2015
Keck Hospital of USC
2015
Stanford University
2015
Brain Mapping Foundation
2008-2013
UCLA Health
2006-2013
Imaging Center
2012-2013
Most traumatic brain injuries (TBIs) are classified as mild (mTBI) based on admission Glasgow Coma Scale (GCS) scores of 13 to 15. The prevalence persistent functional limitations for these patients is unclear.To characterize the natural history recovery daily function following mTBI vs peripheral orthopedic injury in first 12 months postinjury using data from Transforming Research and Clinical Knowledge Traumatic Brain Injury (TRACK-TBI) study, and, clinical computed tomographic (CT) scans,...
<h3>Importance</h3> Traumatic brain injury (TBI) has been associated with adverse mental health outcomes, such as posttraumatic stress disorder (PTSD) and major depressive (MDD), but little is known about factors that modify risk for these psychiatric sequelae, particularly in the civilian sector. <h3>Objective</h3> To ascertain prevalence of PTSD MDD among patients evaluated emergency department mild TBI (mTBI). <h3>Design, Setting, Participants</h3> Prospective longitudinal cohort study...
<h3>Importance</h3> Moderate to severe traumatic brain injury (msTBI) is a major cause of death and disability in the US worldwide. Few studies have enabled prospective, longitudinal outcome data collection from acute chronic phases recovery after msTBI. <h3>Objective</h3> To prospectively assess outcomes areas life function at 2 weeks 3, 6, 12 months <h3>Design, Setting, Participants</h3> This cohort study, as part Transforming Research Clinical Knowledge TBI (TRACK-TBI) was conducted 18...
<h3>Importance</h3> Knowledge of differences in mild traumatic brain injury (mTBI) recovery by sex and age may inform individualized treatment these patients. <h3>Objective</h3> To identify sex-related symptom from mTBI; secondarily, to explore within women, who demonstrate poorer outcomes after TBI. <h3>Design, Setting, Participants</h3> The prospective cohort study Transforming Research Clinical Traumatic Brain Injury (TRACK-TBI) recruited 2000 patients with mTBI February 26, 2014, July 3,...
Abstract The age‐related trends of the width and depth major cortical sulci were studied in normal adults. Ninety healthy subjects (47 males, 43 females) age 20–82 years evaluated. Measurements average sulcal 14 prominent structures per hemisphere performed with high‐resolution anatomical MRI. increased at a rate about 0.7 mm/decade, while decreased 0.4 mm/decade. Sulcal found to be highly influenced by gender superior temporal, collateral, cingulate ( P < 0.05), males showing more...
Brain structural abnormalities and neurocognitive dysfunction have been observed in individuals with fetal alcohol spectrum disorders (FASDs). Little is known about how white matter integrity related to these functional morphological deficits. We used a combination of diffusion tensor T1-weighted magnetic resonance imaging evaluate FASDs findings Seventeen children adolescents were compared 19 typically developing age-and gender-matched controls. Lower fractional anisotropy (FA) was relative...
White matter (WM) mapping of the human brain using neuroimaging techniques has gained considerable interest in neuroscience community. Using diffusion weighted (DWI) and magnetic resonance imaging (MRI), WM fiber pathways between regions may be systematically assessed to make inferences concerning their role normal function, influence on behavior, as well consequences network-level damage. In this paper, we investigate detailed connectomics a noted example severe traumatic injury (TBI) which...
Brain connectivity analyses show considerable promise for understanding how our neural pathways gradually break down in aging and Alzheimer's disease (AD). Even so, we know very little about the brain's networks change AD, which metrics are best to evaluate these changes. To better understand AD affects brain connectivity, analyzed anatomical based on 3-T diffusion-weighted images from 111 subjects (15 with 68 mild cognitive impairment, 28 healthy elderly; mean age, 73.7±7.6 SD years). We...
We used diffusion tensor imaging to investigate fractional anisotropy (FA), a measure of fiber tract integrity, in attention-deficit hyperactivity disorder (ADHD). Using tract-based atlasing approach on six-direction data, we examined FA within the cingulum, corpus callosum, corticospinal tract, fornix, optic radiations, superior longitudinal fasciculus, uncinate and inferior occipitofrontal fasciculi an all-male sample 17 children adolescents with ADHD 16 age-matched controls. patients had...
<h3>Importance</h3> Mild traumatic brain injury (mTBI) affects millions of Americans each year. Lack consistent clinical practice raises concern that many patients with mTBI may not receive adequate follow-up care. <h3>Objective</h3> To characterize the provision care to during first 3 months after injury. <h3>Design, Setting, and Participants</h3> This cohort study used data on enrolled in Transforming Research Clinical Knowledge Traumatic Brain Injury (TRACK-TBI) between February 26, 2014,...