A5042029362- Aortic aneurysm repair treatments
- Aortic Disease and Treatment Approaches
- Cardiac, Anesthesia and Surgical Outcomes
- Vascular Procedures and Complications
- Peripheral Artery Disease Management
- Infectious Aortic and Vascular Conditions
- Diagnosis and Treatment of Venous Diseases
- Wound Healing and Treatments
- Venous Thromboembolism Diagnosis and Management
- Radiation Dose and Imaging
- Acute Ischemic Stroke Management
- Cardiac Valve Diseases and Treatments
- Renal and Vascular Pathologies
- Central Venous Catheters and Hemodialysis
- Protease and Inhibitor Mechanisms
- Entomological Studies and Ecology
- Intracranial Aneurysms: Treatment and Complications
- Electrolyte and hormonal disorders
- Diabetic Foot Ulcer Assessment and Management
- Cardiac tumors and thrombi
- Dermatologic Treatments and Research
- Peripheral Nerve Disorders
- Hip and Femur Fractures
- Electroconvulsive Therapy Studies
- Advanced X-ray and CT Imaging
Guy's and St Thomas' NHS Foundation Trust
2018-2025
St Thomas' Hospital
2006-2024
King's College London
2006-2024
National Health Service
2023
University of Hull
2023
King's College - North Carolina
2021
Kings Health Partners
2019
University of Nottingham
2012-2013
Nottingham University Hospitals NHS Trust
2013
Queen's Medical Centre
2011-2013
Objective: The objective of this study was to evaluate the outcome endovascular aortic arch repair for chronic dissection with a custom-made branched endograft. Background: Acute type A dissections are often treated prosthetic replacement ascending aorta. During follow-up, an aneurysmal evolution false lumen distal prosthesis can be challenge both surgeon and patient. Methods: We conducted multicenter, retrospective consecutive patients from 14 vascular units custom-made, inner-branched...
Radiation exposure during fluoroscopically guided interventions such as endovascular aortic repair (EVAR) is a growing concern for operators. This study aimed to measure DNA damage/repair markers in operators perfoming EVAR.Expression of the marker, γ-H2AX and damage response phosphorylated ataxia telangiectasia mutated (pATM), were quantified circulating lymphocytes peri-operative period (infrarenal, branched, fenestrated) open using flow cytometry. These separately measured same but this...
ObjectiveThis multicenter international study aimed to describe outcomes of fenestrated-branched endovascular aortic repairs (FB-EVAR) in a cohort patients treated for chronic post-dissection thoracoabdominal aneurysms (PD-TAAAs).MethodsWe reviewed the clinical data all consecutive by FB-EVAR repair Extent I-III PD-TAAAs 16 centres from United States and Europe (2008-2021). Data were extracted institutional prospectively maintained databases electronic patient records. All received...
Leiomyosarcoma of the inferior vena cava is a rare tumor that presents in an insidious manner with non-specific symptoms. Given its rarity, there are no consensus guidelines to management. The aim this study was report clinical experience management patients presenting our institution during 12 year period.Four leiomyosarcomas were managed at period reviewed. Patient details identified through search pathology department computerized database, and case notes retrospectively reviewed obtain...
The aim of this study was to examine the effect statin treatment on activity proteases in wall abdominal aortic aneurysms (AAAs).The activities matrix metalloproteinases (MMPs) 9 and 3, cathepsins B, H, K, L S, cystatin C level were measured extracts AAA taken from 82 patients undergoing repair; 21 receiving before surgery. All values standardized against soluble protein (SP) concentration extract, reported as median (interquartile range) or mean(s.e.m.).The two groups had similar...
Objective This UK multicenter study aims to report early- and medium-term results following covered endovascular reconstruction of aortic bifurcation (CERAB) for the treatment aortoiliac occlusive disease (AIOD) in patients with chronic limb threatening ischemia (CLTI) or intermittent claudication (IC). Materials Methods Retrospective case analysis was performed who underwent CERAB between November 1, 2012 March 31, 2020 6 centers across United Kingdom. Anatomical data, including degree...
Abstract Background The presence of fibrous tissue in poorly healing venous leg ulcers suggests abnormal collagen metabolism. aim was to determine whether there were differences turnover and matrix metalloproteinase (MMP) activity between that healed, those did not heal normal skin. Methods Biopsies taken from the 12 patients whose went on 15 failed despite months compression bandaging. controls. Collagen (collagen III N-terminal propeptide (PIIINP) degraded collagen), total MMP, MMP-1 MMP-3...
BackgroundPercutaneous transluminal angioplasty (PTA) is a common procedure in patients with peripheral arterial disease (PAD) affecting the femoropopliteal segment (F-P). Biomimetic nitinol stents (Supera stent, SPS) and drug eluting (DES) were designed to improve longevity of F-P PTA; however, their performance has not been compared pragmatic setting, taking atherosclerotic plaque characteristics into account.MethodsOverall, 296 consecutive (mean age: 73 y, SD: 11 65% male, 68% chronic...
The aim of this study was to determine the success excision and meshed skin grafting for chronic leg ulcers. effects different ulcer aetiology size on outcome were also assessed.All patients who had mesh ulceration between January 1996 December 2004 at St Thomas' Hospital reviewed. Recurrence classified as any breakdown during follow-up.Sixty-two with 100 ulcers underwent operation. Seventy-two venous median 36 (range 1.5-192) cm2. Only three left hospital their unhealed, but recurred in 28...
Objective: The main objective of this study is to present the experience 2 centers undertaking total percutaneous aortic arch-branched graft endovascular repair using combination femoral and axillary routes. report summarizes procedural steps, outcomes achieved, benefits approach, which eliminates need for direct open surgical exposure carotid, subclavian, or arteries, thereby reducing unnecessary associated risks. Methods: Retrospectively collected data 18 consecutive patients (15M:3F)...
Recent international guidance recommends the use of catheter-directed thrombolysis (CDT) in selected patients with symptomatic iliofemoral deep vein thrombosis (DVT). The aim this study was to estimate potential increase workload as a result recommendation.Using radiology database, review performed all DVTs diagnosed between August 2010 and February 2012 at large tertiary referral hospital. National Institute for Health Clinical Excellence American College Chest Physicians applied...