A5100449808- Photorefractive and Nonlinear Optics
- Liver Disease Diagnosis and Treatment
- Advanced Fiber Laser Technologies
- Vacuum and Plasma Arcs
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Photonic Crystals and Applications
- Photonic and Optical Devices
- Electrical Fault Detection and Protection
- COVID-19 epidemiological studies
- Marine animal studies overview
- Mental Health Research Topics
- Mobile Health and mHealth Applications
- Health Systems, Economic Evaluations, Quality of Life
- Emergency and Acute Care Studies
- Vaccine Coverage and Hesitancy
- Advanced materials and composites
- Second Language Acquisition and Learning
- SARS-CoV-2 and COVID-19 Research
- Healthcare Policy and Management
- Virology and Viral Diseases
- Radiation Detection and Scintillator Technologies
- Particle Detector Development and Performance
- EFL/ESL Teaching and Learning
- Mental Health Treatment and Access
University of Washington
2016-2025
Ningxia Medical University General Hospital
2025
Ningxia Medical University
2025
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
2022-2025
Huazhong University of Science and Technology
2020-2025
First People's Hospital of Yunnan Province
2025
Kunming University of Science and Technology
2025
Zhejiang Chinese Medical University
2023-2025
Shanxi University
2023-2025
Bengbu Medical College
2025
Background: Chronic hepatitis C virus is difficult to treat and affects approximately 3 million Americans. Protease inhibitors increase the effectiveness of standard therapy, but they are costly. A genetic assay may identify patients most likely benefit from this treatment advance. Objective: To assess cost-effectiveness new protease an interleukin (IL)–28B genotyping for treating chronic virus. Design: Decision-analytic Markov model. Data Sources: Published literature expert opinion. Target...
Purpose – Although the health information seeking behavior of consumers through internet has received great attention, limited attempt been made to integrate both and usage in a mobile online context. The purpose this paper is explore factors that influence consumer (MHIS) based on quality, perceived value, personal trust. Design/methodology/approach A survey was conducted collect data. two-step approach structure equation modeling used test measurement model hypothesis model. Findings...
Introduction: Thrombolysis with intravenous tissue plasminogen activator (tPA) is the only FDA approved treatment for patients acute ischemic stroke, but its use limited by narrow therapeutic window, selective efficacy, and hemorrhagic complication. In past two decades, extensive efforts have been undertaken to extend time window explore alternative thrombolytic agents, both show little progress. Nanotechnology has emerged as a promising strategy improve efficacy safety of tPA.Areas covered:...
Abstract Generation of coherent light with desirable amplitude and phase profiles throughout the optical spectrum is a key issue in technologies. Nonlinear wavefront shaping offers an exceptional way to achieve this goal by converting incident beam into (or beams) different frequency spatially modulated phase. The realization such conversion processes critically depends on matching velocities interacting waves, for which nonlinear photonic crystals (NPCs) quadratic nonlinearity have shown...
Tunable valence state and scintillation properties from Ce-doped gadolinium aluminoborosilicate glass scintillators for high-energy physics applications.
Background: Prevalence of chronic hepatitis C virus (HCV) infection is high among incarcerated persons in the United States. New, short-duration, high-efficacy therapies may expand treatment eligibility this population. Objective: To assess cost-effectiveness sofosbuvir for HCV populations. Design: Markov model. Data Sources: Published literature and expert opinion. Target Population: Treatment-naive men with chronic, genotype 1 monoinfection. Time Horizon: Lifetime. Perspective: Societal....
Sustained activation of autophagy and lipid accumulation in tubular epithelial cells (TECs) are both associated with the kidney fibrosis progression. Autophagy has been found involved metabolism regulation through a bi-directional mechanism inducing lipolysis as well promoting droplet formation. However, whether how influences remain unclear. In current study, we show that UUO-induced was significantly reduced when pharmacological inhibitor 3-MA or CQ administrated vivo vitro. Of interest,...
Abstract Nonlinear photonic crystals (NPCs) with spatially modulated second‐order nonlinear coefficients are indispensable in optics and modern photonics. To access full degrees of freedom the generation control coherent light at new frequencies, three dimensional (3D) NPCs have been recently fabricated employing femtosecond laser writing technique ferroelectric crystals. However, interaction efficiencies 3D so far rather low, which has a major barrier to further development. Here,...
Knee osteoarthritis (KOA) constitutes the prevailing manifestation of arthritis. Radiographs function as a common modality for primary screening; however, traditional X-ray evaluation confronts challenges such reduced sensitivity, subjective interpretation, and heightened misdiagnosis rates. The objective this investigation is to enhance validation optimization accuracy efficiency in KOA assessment by utilizing fusion deep learning techniques. This study aims develop highly accurate...
Background No consensus exists on screening to detect the estimated 2 million Americans unaware of their chronic hepatitis C infections. Advisory groups differ, recommending birth-cohort for baby boomers, only high-risk individuals, or no screening. We assessed one-time risk assessment and identify previously undiagnosed 40–74 year-olds given newly available treatments. Methods Findings A Markov model evaluated alternative risk-factor guided treatment strategies. Risk factors included drug...
Upper airway stimulation (UAS) is a new approach to treat moderate-to-severe obstructive sleep apnea. Recently, 12-month data from the Stimulation Treatment for Apnea Reduction (STAR) trial were reported, evaluating effectiveness of UAS in patients intolerant or non-adherent continuous positive pressure therapy. Our objective was assess cost-effectiveness U.S. payer perspective. A 5-state Markov model used predict cardiovascular endpoints (myocardial infarction [MI], stroke, hypertension),...
Abstract Nonlinear photonic crystals (NPCs) are transparent materials with a space‐dependent (often periodic) second‐order nonlinearity, which have been used extensively for the generation and control of coherent light at new frequencies. Thanks to recently introduced fabrication techniques capable 3D nonlinearity engineering, explorations nonlinear wave interaction improved or unique functionalities configurations become possible. Here, experimental example volume holography based on NPCs...
Background: Older adults constitute a large and growing proportion of the population have unique care needs in emergency department (ED) setting. The geriatric ED accreditation program aims to improve provided older by standardizing across accredited EDs (GED) through implementation geriatric-specific processes.
Background and Aims Chronic hepatitis C (HCV) is a liver disease affecting over 3 million Americans. Liver biopsy the gold standard for assessing fibrosis used as benchmark initiating treatment, though it expensive carries risks of complications. FibroTest non-invasive biomarker assay fibrosis, proposed screening alternative to biopsy. Methods We assessed cost-effectiveness alone or sequentially six strategies followed by treatment eligible U.S. patients: only; with ambiguous results; rule...
Nonlinear wavefront shaping in periodically poled ferroelectric crystals has received great attention because it offers a convenient way to generate structured light beam at new frequencies. In contrast structurally uniform beams like Laguerre-Gaussian or Hermite-Gaussian modes, here we demonstrate the possibility spatially varied optical bottle via frequency doubling process domain-engineered Sr0.61Ba0.39Nb2O6 (SBN) crystal. The nonlinear holography method was employed design modulation...