- Trypanosoma species research and implications
- Mosquito-borne diseases and control
- Iron Metabolism and Disorders
- Research on Leishmaniasis Studies
- Child Nutrition and Water Access
- Malaria Research and Control
- Maternal and Neonatal Healthcare
- Parasites and Host Interactions
- Insect symbiosis and bacterial influences
- Indigenous Health and Education
- Science and Education Research
- Cardiomyopathy and Myosin Studies
- Hemoglobinopathies and Related Disorders
- Parasitic Infections and Diagnostics
- Phytochemistry Medicinal Plant Applications
- Streptococcal Infections and Treatments
- Enterobacteriaceae and Cronobacter Research
- Venomous Animal Envenomation and Studies
- Education during COVID-19 pandemic
- Complement system in diseases
- Cell Adhesion Molecules Research
- Environmental and biological studies
- Otolaryngology and Infectious Diseases
- Global Health and Surgery
- Hematological disorders and diagnostics
Instituto Evandro Chagas
2004-2022
Ministério da Saúde
2003-2022
Ministério da Saúde
2009-2021
Fundação Oswaldo Cruz
2016
University of Palermo
2008
Secretaria da Saúde
2007
Hospital Clínico Universitario de Caracas
2006
Universidade do Estado do Pará
2004
Universidade Federal do Pará
2003
Fundação Saúde
2001
Chagas disease is a neglected chronic condition with high burden of morbidity and mortality. It has considerable psychological, social, economic impacts. The represents significant public health issue in Brazil, different regional patterns. This document presents the evidence that resulted Brazilian Consensus on Disease. objective was to review standardize strategies for diagnosis, treatment, prevention, control country, based available scientific evidence. consensus articulation strategic...
Chagas disease is a neglected chronic condition that presents high morbidity and mortality burden, with considerable psychological, social, economic impact.The represents significant public health issue in Brazil, different regional patterns.This document the evidence resulted Brazilian Consensus on Disease.The objective was to review standardize strategies for diagnosis, treatment, prevention, control of country, based available scientific evidence.The consensus collaboration contribution...
Foram estudados 233 casos de fase aguda da doença Chagas, oriundos do Pará, Amapá e Maranhão, observados no período 1988 a 2005, cento sessenta deles retrospectivamente 2002 setenta três prospectivamente 2003 2005. Entre os 78,5% (183/233) faziam parte surtos provavelmente por transmissão oral, acometendo em média 4 pessoas 21,5% (50/233) eram isolados. considerados agudos aqueles que apresentaram exames parasitológicos diretos (a fresco, gota espessa ou Quantitative Buffy Coat - QBC) e/ou...
An outbreak of Chagas disease occurred in Mazagão, Amapá, Brazilian Amazon 1996. Seventeen 26 inhabitants presented symptoms compatible with acute and were submitted to parasitological serological tests. All 17 positive at least one test 11 also IgM or IgG anti-Trypanosoma cruzi positive. The nine asymptomatic patients negative for parasites was anti-T. cruzi. Sixty-eight triatomines captured (66 Rhodnius pictipes; two Panstrongylus geniculatus); 45 infected T. (43 R. P. geniculatus)....
Lista de Siglas/Abreviaturas 18 F-FDG – fluordesoxiglicose marcado com flúor-18 123 I-MIBG meta-iodo-benzil-guanidina iodo-123 […] Diretriz da SBC sobre Diagnóstico e Tratamento Pacientes Cardiomiopatia Doença Chagas 2023
Abstract Oropouche fever has reemerged in Parauapebas and Porto de Moz municipalities, Pará State, Brazil. Serologic analysis (immunoglobulin M–ELISA) virus isolation confirmed (OROV) both municipalities. Nucleotide sequencing of 2 OROV isolates from each location indicated genotypes I (Parauapebas) II (Porto Moz)
Four cases of serious cardiac attacks by autochthonous Trypanosoma cruzi infection from the Brazilian Amazon are reported; three them occurred in micro-epidemic episodes. The manifestations included sudden fever, myalgia, dyspnea and signs heart failure. Diagnosis was confirmed specific exams, especially QBC (Quantitative Buffy Coat) natural xenodiagnosis. Despite treatment with benznidazol, patients died myocarditis, renal failure tamponade. authors call attention to emergence this disease...
Acute Chagas disease (ACD) is caused by Trypanosoma cruzi. ACD outbreaks due to probable oral transmission occur regularly in small family gatherings that are exposed contaminated foods. We studied two cohorts of residents on islands the Breves and Bagre municipalities, July August 2007, identify risk factors recommend preventative measures. Of 25 cases identified both cohorts, 13 (52%) were men, most frequent symptoms fever (96%),asthenia (80%), myalgia (76%), abdominal pain (64%),...
The objective of this report is to describe treatment outcomes over a four-year period patients with acute Chagas disease in the Amazon region Brazil. An outbreak low-income district urban Belém, September 2000, affected 11 people simultaneously, indicating likelihood indirect, oral transmission Trypanosoma cruzi. Prior treatment, underwent physical and clinical tests; blood samples were processed immunofluorescence assay (IFA) quantitative buffy coat (QBC). Following benznidazole,...
A total of 179 individuals with acute Chagas disease mainly transmitted by oral source, from Pará and Amapá State, Amazonian, Brazil were included during the period 1988 to 2005. Blood samples used survey peripheral blood for T. cruzi hemoparasites quantitative buffy coat (QBC), indirect xenodiagnosis, culture serology detection IgM anti-T. IgG antibodies immunofluorescence assay (IFA) hemagglutination (HA). All assays performed pre-treatment (0 days) repeated 35 (±7) 68 (±6) days after...
Os autores mostram os principais achados clínicos relativos ao acometimento cardíaco, em pacientes portadores de doença Chagas aguda mais um episódio microepidemia familiar na Amazônia brasileira. Foram estudados 13 com aguda, procedentes do município Abaetetuba-PA e submetidos à avaliação clínica cardiológica, eletrocardiograma ecocardiograma. As extra-sístoles supraventriculares e/ou ventriculares ocorreram 38,5% dos casos. Bloqueios ramo direito bloqueios átrio-ventriculares 1º 2º graus,...
Recaídas que podem ocorrer com o tratamento convencional de longa duração para malária por P. vivax, são em parte devido a parcial adesão do paciente ao tratamento. A utilização esquemas terapêuticos curta pode proporcionar melhor tratamento, mantendo eficácia e tolerância minimizando efeitos adversos. Com objetivo testar 2 doses reduzidas cloroquina P.vivax , comparando-o esquema clássico, os autores estudaram 120 pacientes, diagnosticados pela gota espessa, idade superior 12 anos,...
with the objective of evaluating shortened therapeutic outlines effective in vivax malaria treatment, we accomplished an open, prospective study allocating 234 patients distributed at random into eight groups. Six groups used oral arthemisin as blood esquizonticide different doses for one day and other two received chloroquine a single dose. The primaquine was hypnozoiticide all They daily dose 30mg course five or seven days clearance parasitaemia treated (independent dosage) faster than...
Reação cruzada nos testes sorológicos entre doença de Chagas e leishmaniose visceral em regiões endêmicas para ambas as doençasReacción en las pruebas serológicas
ABSTRACT A family of four, including a 24-year-old female, presented to our laboratory in December 2006 with prolonged febrile syndrome unknown etiology. After extensive screening, acute Chagas disease was confirmed by positive T. cruzi blood culture, combined clinical, epidemiological and serological findings. The young her parents husband received daily dose benznidazole, but she developed serious drug intolerance amenorrhea. Her treatment interrupted pregnancy about 12 weeks gestational...
OBJETIVOS: Destacar o perfil clínico-laboratorial de malária e hepatite aguda viral em dois grupos crianças, ressaltando semelhanças diferenças entre os quadros; subsidiar aumento da sensibilidade clínica presunção diagnóstica precoce na infância. MÉTODOS: Foram estudados 30 a dez anos idade, portadoras primo infecção malárica ou aguda, confirmados pela pesquisa plasmódio marcadores virais A B. As crianças foram submetidas às seguintes avaliações no primeiro dia atendimento: hemograma,...
ABSTRACTThis article aims to assess the cardiac impairment associated with acute infections by Trypanosoma considering conduction abnormalities and rhythm during phase of disease after treatment in a case series study Chagas' indigenous Amazon. The individuals included this were grouped into two cohorts: cohort I comprised patients undergoing stage disease; II same re-evaluated an average period 3.9 years treatment. electrocardiographic evaluation was based both on restored...
Dupla abordagem de infecções por Trypanosoma cruzi e/ou Plasmodium spp.aplicada ao diagnóstico doença Chagas e exposição vetorial triatomínica na Amazônia brasileira Dual approach of and
Malaria regions of the Amazon basin have been characterized by difficult access and non-compliance patients to treatment. In an attempt assess schizonticide efficacy chloroquine in a single dose 600 mg, authors realized double-blind, placebo-controlled trial 132 outpatients with vivax malaria. Patients were distributed into two groups: group CPLA, given mg (single dose) on first day treatment, doses placebo second third days. Group CHLO, 450 day. Geometric means parasite density during...