A5024711093- Schizophrenia research and treatment
- Tryptophan and brain disorders
- Stress Responses and Cortisol
- Treatment of Major Depression
- Diet and metabolism studies
- Advanced Neuroimaging Techniques and Applications
- Physical Activity and Health
- Family Support in Illness
- Mental Health Treatment and Access
- Substance Abuse Treatment and Outcomes
- Cancer survivorship and care
- Child and Adolescent Psychosocial and Emotional Development
- Obesity, Physical Activity, Diet
- Palliative Care and End-of-Life Issues
- Maternal Mental Health During Pregnancy and Postpartum
- Mental Health Research Topics
- Eating Disorders and Behaviors
- Mental Health and Psychiatry
The University of Melbourne
2015-2024
Orygen
2023-2024
Orygen Youth Health
2015-2020
Abstract Background Inflammation contributes to the pathophysiology of major depressive disorder (MDD), and anti-inflammatory strategies might therefore have therapeutic potential. This trial aimed determine whether adjunctive aspirin or rosuvastatin, compared with placebo, reduced symptoms in young people (15–25 years). Methods YoDA-A, Youth Depression Alleviation Anti-inflammatory Agents, was a 12-week triple-blind, randomised, controlled trial. Participants were (aged 15–25 years)...
Clinical trials have not established the optimal type, sequence, and duration of interventions for people at ultrahigh risk psychosis.
Abstract Aim There is growing support for the role of inflammation and oxidative stress in pathophysiology major depressive disorder (MDD). This has led to development novel strategies targeting treatment depression. Rosuvastatin aspirin have well‐documented, anti‐inflammatory antioxidant properties. The aim Y outh D epression A lleviation: Augmentation with an agent ( YoDA‐A ) study determine whether individuals receiving adjunctive agents, rosuvastatin experience a reduction severity MDD...
Since the late 1990s, there has been a worldwide surge of scientific interest in pre-psychotic phase, resulting introduction several clinical tools for early detection. The predictive accuracy these limited, motivating need methodological and perspectival improvements. EASE manual supports systematic assessment anomalous self-experience, proposes an overall model understanding how most psychotic experiences may be initially generated on basis unifying, fundamental, pre-reflective distortion...
Aims: Both substance use and mental illness commonly onset during adolescence or young adulthood, rates of in people with are disproportionately high. This baseline data paper from a clinical trial testing an integrated early intervention for health problems aims to 1) describe the characteristics participants enrolled; 2) compare current without lifetime diagnosis Substance Use Disorder (SUD) terms psychiatric symptoms, functioning, use. Methods: Seventy-nine aged 12-25 years high...