A5025904295- Digital Radiography and Breast Imaging
- Advanced X-ray and CT Imaging
- Medical Imaging Techniques and Applications
- Lung Cancer Diagnosis and Treatment
- Advanced MRI Techniques and Applications
- MRI in cancer diagnosis
- Radiation Dose and Imaging
- Radiomics and Machine Learning in Medical Imaging
- Radiology practices and education
- Atomic and Subatomic Physics Research
- AI in cancer detection
- Breast Lesions and Carcinomas
- Shoulder Injury and Treatment
- Antifungal resistance and susceptibility
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Orthopedic Surgery and Rehabilitation
- Advanced Radiotherapy Techniques
- Fungal Infections and Studies
- Peripheral Artery Disease Management
- Disaster Response and Management
- Shoulder and Clavicle Injuries
- Aortic aneurysm repair treatments
- Venous Thromboembolism Diagnosis and Management
- Cancer Diagnosis and Treatment
- Photoacoustic and Ultrasonic Imaging
Charité - Universitätsmedizin Berlin
2002-2023
Humboldt-Universität zu Berlin
2002-2022
Freie Universität Berlin
2022
University of Göttingen
1995-2000
Auguste-Viktoria-Klinik
2000
Klinikum St. Georg
2000
Fischer (Germany)
1996
Leiden University
1991-1994
Universitätsmedizin Göttingen
1994
Medizinische Hochschule Hannover
1987-1993
Voriconazole is a broad-spectrum triazole that active against aspergillus species. We conducted randomized trial to compare voriconazole with amphotericin B for primary therapy of invasive aspergillosis.
Background.Computed tomography (CT) of the chest may be used to identify halo sign, a macronodule surrounded by perimeter ground-glass opacity, which is an early sign invasive pulmonary aspergillosis (IPA). This study analyzed CT findings at presentation from large series patients with IPA, assess prevalence these imaging and evaluate clinical utility for identification this potentially life-threatening infection. Methods.Baseline 235 IPA who participated in previously published were...
Purpose Our goal was to demonstrate possible pitfalls in the CT diagnosis of retained surgical sponges (textilomas) and evaluate impact gas bubbles inside a textiloma. Method Thirteen patients with textilomas were investigated 3 weeks 8 years after surgery. Twelve 13 removed within first examination. Eight samples placed water bath for 6 months. Serial performed document presence persistence bubbles. Results The radiopaque marker textiloma seen nine but did not lead all patients. In seven...
PURPOSE: To evaluate the effects of tracking and volume contrast material on dual-phase helical computed tomography (CT) liver. MATERIALS AND METHODS: CT was performed in 120 consecutive patients. Either 100 mL (groups 1 2) or 3 4) injected at a rate 4 mL/sec. In groups 3, scanning delay fixed, whereas 2 4, delays were determined individually by means semiautomatic bolus device. The arterial phase began when splenic enhancement greater than 10 HU ended hepatic 20 HU, which characterized...
The influence of viewing time on the detectability subtle and obvious lung cancers was studied. Frontal chest radiographs 40 patients with cancers, healthy control subjects were shown to four observers for different times (0.25 second, 1 4 seconds, unlimited time). Receiver operating characteristic analysis used compare lesions. Performance degraded as decreased. true-positive fractions 30% 70% at 0.25 second 74% 98% time, respectively, a given false-positive fraction 20%. Thus, even...
We determined whether contrast-enhanced color Doppler sonography can differentiate benign from malignant enlarged cervical lymph nodes in head and neck tumors.Ninety-four 39 adult patients (32 men seven women; age range, 30-81 years) were examined with B-mode unenhanced sonography. All had carcinoma of the oral cavity. Histologically, lymphadenitis was found 57 metastases 37 nodes. Geometric dimension, texture, margin node detection location vessels noted. Histology imaging findings...
A major concern about combined pulmonary CT angiography (PCTA) and venography (CTV) refers to the additional radiation exposure patient. The purpose of this paper is analyze organ dose, effective gonadal dose PCTA CTV. Effective in CTV were calculated. Also measured was doses with thermoluminescence dosimeters six patients who underwent PCTA/CTV. risk from PCTA/CTV low. Nevertheless, increases by a significant factor use procedure should be limited younger patients.
To assess the value of dynamic magnetic resonance (MR) imaging in patients with mammographically detected suspicious microcalcifications.Sixty-three (age range, 31-84 years; mean age, 56 years) clustered microcalcifications underwent MR breast before surgical biopsy. was performed a 1.5-T unit and two-dimensional fast low-angle shot sequence flip angle 80 degrees. Thirty-two axial sections, 4 mm thick without interval gaps, were acquired five times after administration gadopentetate...
PURPOSE: To evaluate two different systems for magnetic resonance (MR) imaging-guided breast intervention. MATERIALS AND METHODS: Thirty-four patients with 34 lesions detected exclusively contrast material-enhanced MR imaging underwent 51 interventional procedures (23 needle biopsies and 28 preoperative wire localizations) systems. An add-on device surface coils was used in 25 cases, a dedicated single biopsy coil 26. For biopsies, material aspirated nonmagnetic 19.5-gauge needles....
PURPOSE: To evaluate the usefulness of broadband ultrasound attenuation in prediction osteoporosis. MATERIALS AND METHODS: Broadband measurements calcaneus and dual x-ray absorptiometry (DXA) lumbar spine femoral neck were obtained 400 patients (295 female 105 male), 135 whom classified as having Correlation coefficients between DXA calculated. RESULTS: Patients with osteoporosis showed a statistically significant decrease compared healthy (59.7 dB/MHz +/- 1.3 [standard deviation] vs 75.1...
A guiding attachment is described that transforms a conventional magnetic resonance (MR) imaging surface coil into stereotaxic biopsy unit. Eight patients, aged 38-66 years (mean, 54 years), with suspect breast lesions detected exclusively at contrast material-enhanced MR underwent MR-guided needle this Diagnostic material was successfully aspirated in all patients (four carcinomas, three fibroadenomas, and one intraductal hyperplasia), the diagnosis subsequently confirmed surgical biopsy....
MR arthrography of the shoulder with gadopentetate dimeglumine: influence concentration, iodinated contrast material, and time on signal intensity.L Kopka, M Funke, U Fischer, D Keating, J Oestmann E GrabbeAudio Available | Share
The diagnostic performance of high-field-strength magnetic resonance (MR) imaging (1.5 T) for detection liver metastases was compared with that computed tomography (CT). All patients (n = 52) underwent preoperative screening by means MR T1-weighted, proton-density-weighted, and T2-weighted pulse sequences CT scanning unenhanced, incremental dynamic bolus-enhanced, delayed contrast medium-enhanced techniques. Diagnostic evaluated receiver operating characteristic analysis in which 800 images...
PURPOSE: To measure infrarenal abdominal aortic aneurysms and assess the implications potential obstacles for placement of an endovascular graft undergoing clinical testing in Europe. MATERIALS AND METHODS: Helical computed tomography was used to 77 (77 patients) distances between renal arteries bifurcation. RESULTS: Mean length 8.2 cm; mean distance arteries, 2.7 diameter 1.5 cm distal 1.9 minimal perfused lumen, 2.5 cm. Thirteen extended into common iliac artery; 40 reached The luminal...
The advantages of imaging the chest with digital storage phosphor radiography (SR) may be nullified by its spatial resolution, which is lower than that conventional film (FR). To test reader detection performance two modalities under clinical conditions, authors compared 140-kVp isoexposure SR (system resolution: 0.2 mm, 10 bits) and FR images a variety abnormalities proved computed tomography (CT) (157 patients, 244 abnormalities, 5,652 observations, six readers). In all tests, was as good...
The aim of this study was to evaluate the roles 67Ga-citrate and 99Tcm-methylene diphosphonate (99Tcm-MDP) planar single photon emission tomographic (SPET) imaging in patients with vertebral osteomyelitis. Thirty (22 females, 8 males) aged 62.7±16.4 years (mean±s) were enrolled prospectively between May 1995 1998. had been on antibiotics for 7±4 weeks prior study. Histology available all but nine mild infections, who evaluated by a combination magnetic resonance (MRI), clinical laboratory...
To evaluate age- and gender-related mechanical properties bone mineral density (BMD) of the proximal humerus at different levels regions.Mechanical indentation testing, DXA, QCT, pQCT radiogrammetry (Cortical Index, CI) were carried out in 70 freshly harvested humeri from 46 human cadavers (23 females, 23-males; median age 70.5 years).In female group, a high correlation between BMD was found (rho = 0.62 to -0.70, p < 0.01) with statistically significant differences specimens patients 69...
The detectability of malignant tumor-derived microcalcifications with conventional mammography was compared to that digital images (2000×2510 pixels by 10 bits) derived from a storage phosphor–based radiography system capable 5 line pair/mm resolution at identical exposure factors (30 kVp, 250 mAs, 65 cm film–focus distance). Microcalcifications (50–800 microns in diameter) were randomly superimposed on preserved human breast specimen. ROC analysis based 480 observations made four readers...
A software-driven device for bolus-triggered start of helical computed tomography (CT) was evaluated in liver studies 30 patients with suspected metastatic disease. Compared results a control group who underwent conventional contrast material-enhanced CT, the study had significantly higher and more constant parenchymal enhancement (P < .05, Mann-Whitney U test). This technique helps optimize findings at contrast-enhanced CT.
Observer performance with four unsharp mask filtering algorithms for storage phosphor chest radiographs was compared that conventional screen-film in the detection of three types simulated lung disease: nodules, fine lines, and micronodule clusters. Previously studied parameter sets (small [1.4-mm] medium [5-mm] filter masks) two new (large [2.5-cm] ultralarge [7-cm] were by means receiver operating characteristic analysis. With small masks, nodule inferior to achieved other modes. Use masks...
Diagnostic performance with storage phosphor radiography is influenced by exposure parameters and digital filtering algorithms. The authors compared the detectability of cortical lesions in excised human femoral shafts on state-of-the-art screen-film radiographs radiographs. For system, effect varying (photon flux tube voltage) unsharp mask (kernel size enhancement factor) was tested. Analysis receiver operating characteristics performed for 10,560 observations made eight radiologists. Under...