A5040661891- Dementia and Cognitive Impairment Research
- Alzheimer's disease research and treatments
- Blood Pressure and Hypertension Studies
- Alcoholism and Thiamine Deficiency
- Spatial Neglect and Hemispheric Dysfunction
- Aging, Health, and Disability
- Heart Rate Variability and Autonomic Control
- Epilepsy research and treatment
- Frailty in Older Adults
- Functional Brain Connectivity Studies
- Genetic Neurodegenerative Diseases
- Neurological Disorders and Treatments
- Glioma Diagnosis and Treatment
- Glycogen Storage Diseases and Myoclonus
- Medical research and treatments
- Memory and Neural Mechanisms
- Cardiovascular Health and Disease Prevention
- RNA modifications and cancer
- Pharmacological Effects and Toxicity Studies
Clinica Universidad de Navarra
2015-2025
Universidad de Navarra
2016
Early-onset Alzheimer disease (EOAD), which presents in patients younger than 65 years, has frequently been described as having different features from those of late-onset (LOAD). This review analyses the most recent studies comparing clinical presentation and neuropsychological, neuropathological, genetic, neuroimaging findings both types order to determine whether EOAD LOAD are entities or distinct forms same entity. We observed consistent differences between LOAD. Fundamentally, onset is...
Abstract Purpose Amnestic mild cognitive impairment (aMCI) is considered a precursor to Alzheimer’s disease (AD). Since cerebral amyloid aggregation and neurodegeneration can be detected at an early stage, it serve as diagnostic aid. This study aimed determine the predictive value of Amyloid-PET FDG-PET in determining progression AD among patients with aMCI. Methods recruited 145 aMCI from October 2013 March 2021. The were classified into four groups based on whether (A) (N) positive (+) or...
(1) Background: Both cerebral vascular disorders and cognitive decline increase in incidence with age. The role of disease hemodynamic changes the development deficits is controversial. objective this study was to assess cardiovascular response during cardiac stress testing neurologically asymptomatic individuals who developed impairment several years after previous testing. (2) Methods: This a retrospective cohort patients underwent between January 2001 December 2010. Patients were followed...
Abstract Background Alzheimer disease (AD) is the most common cause of dementia worldwide. It known that cerebral amyloid aggregation and neurodegeneration are first steps in physiopathology AD. In prodromal phase, a clinical diagnosis amnesic mild cognitive impairment (aMCI) can be stablished, but not all subjects with MCI have The objective this study was to determinate impact FDG PET on progression from aMCI AD dementia. Methods From October 2013 March 2021, we prospectively selected 145...
Preclinical, prodromal and dementia. In the phase, a clinical diagnosis of mild cognitive impairment (MCI) can be stablished. However, not all subjects with MCI have AD. Distinct groups proposed classifications that incorporate biomarkers to better diagnose this early AD phase. We wanted determinate utility IWG-2 NIA-AA using neuroimaging in practice, their impact on conversion selected 96 patients from our Memory Clinic. excluded older than 85 those structural brain lesion. Participants...
Abstract Background: Both cerebral vascular disorders and cognitive decline increase in incidence with age. The role of disease hemodynamic changes the development deficits is controversial. objective this study was to assess cardiovascular response during cardiac stress testing neurologically asymptomatic individuals who developed impairment several years after testing. Methods: This a retrospective cohort patients underwent between January 2001 December 2010. Patients were followed up...