A5035605418- Respiratory viral infections research
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Cystic Fibrosis Research Advances
- Respiratory Support and Mechanisms
- Neonatal Respiratory Health Research
- Ethics and Legal Issues in Pediatric Healthcare
- Neurogenetic and Muscular Disorders Research
- Cardiac Arrest and Resuscitation
- Congenital Anomalies and Fetal Surgery
- Global Health and Surgery
- RNA modifications and cancer
- Migraine and Headache Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Hearing, Cochlea, Tinnitus, Genetics
- Pleural and Pulmonary Diseases
- Trigeminal Neuralgia and Treatments
- Ophthalmology and Eye Disorders
- Lung Cancer Diagnosis and Treatment
- Maternal and fetal healthcare
- Cardiovascular Syncope and Autonomic Disorders
- Trauma and Emergency Care Studies
- Global Maternal and Child Health
- Maternal and Perinatal Health Interventions
- Immunodeficiency and Autoimmune Disorders
Mediclinic City Hospital
2021-2024
Queen's Hospital
2022
Mohammed Bin Rashid University of Medicine and Health Sciences
2020-2021
Ministry of Health
2019
Groote Schuur Hospital
2018
University of Cape Town
2018
Population Health Research Institute
2018
University of KwaZulu-Natal
2018
National Hospital Niamey
2018
McMaster University
2018
Maternal and neonatal mortality is high in Africa, but few large, prospective studies have been done to investigate the risk factors associated with these poor maternal outcomes.A 7-day, international, prospective, observational cohort study was patients having caesarean delivery 183 hospitals across 22 countries Africa. The inclusion criteria were all consecutive (aged ≥18 years) admitted participating centres elective non-elective during 7-day period. To ensure a representative sample,...
COVID-19 has infected over 123 million people globally. The first confirmed case in the United Arab Emirates (UAE) was reported on January 29, 2020. According to studies conducted early epicenters of pandemic, fared mildly pediatric population. To date, there is a lack published data about infection among children Arabian region.This study aims investigate clinical characteristics, laboratory findings, treatment, and outcomes with COVID-19.This cross-sectional, multicenter included admitted...
Spinal muscular atrophy (SMA) manifests with progressive motor neuron degeneration, leading to muscle weakness. Onasemnogene abeparvovec is a US Food and Drug Administration-approved gene replacement therapy for SMA. This study aimed present short-term data of children in the United Arab Emirates (UAE) treated onasemnogene abeparvovec, particularly context requiring invasive ventilatory support via tracheostomy.
Patients with spinal muscular atrophy type 1 (SMA-1) requiring invasive ventilation can be eligible for gene therapy if they tolerate at least 8 h off per day. We aimed to assess the short-term safety and efficacy of (onasemnogene abeparvovec; Zolgensma) on respiratory function in SMA-1 patients ventilated via tracheostomy pre-gene therapy. A prospective cohort study included 22 patients. were weaned daily by optimizing ventilator settings duration, using cough augmentation, managing...
Tobacco in any form is harmful. There an alarming increase consumption of Alternative Products (ATPs). Midwakh one the most used ATP UAE, particularly amongst adolescents. In addition to harmful levels cobalt, chromium, cadmium, Iron and lead, has higher nicotine tar content when compared shisha cigarettes. We report a 14-year-old adolescent male, who presented with Acute Lung Injury within 24 hours following first attempt smoking, presentation remarkably similar E-Cigarettes or Vaping...
<b>Background:</b> Hearing loss is a major health and social problem that affects everyday life.Patients with Cystic Fibrosis (CF) are at high risk of hearing as result receiving multiple courses aminoglycoside antibiotics.In addition some patients also carry the mitochondrial mutation m.1555A>G which leads to severe rapid onset when exposed aminoglycosides.Identifying essential early recognize, prevent treat. <b>Aim:</b> To evaluate current practice assessment in CF among UK centers....
MethodsData were prospectively collected from 975 eligible patients (554 females; 583 Caucasians; age range = 4.5-18.1 years) with headaches.Patients included only if they > 4 years old and had suffered headache course for 6 months or 5 separate attacks.We have adopted previous descriptions of terms anatomical sites location [1].Side locked unilateral (SLUH) is defined as a that all time fixed unilaterally never changed side.Headache diagnosis was made on the basis ICHD -II, 2004...
Midwakh is one of the most used alternative tobacco products (ATPs) in UAE, particularly among adolescents. We report a 14-year-old adolescent male, who presented with acute lung injury within 24 hours following first attempt at smoking. A high-resolution computerized tomogram chest (HRCT) showed bilateral interstitial pneumonia and patchy consolidation. Flexible bronchoscopy revealed petechial haemorrhages oedematous bronchial walls. Mechanical ventilation was required for two weeks. The...
Abstract Background To date, coronavirus disease-2019 (COVID-19) has infected over 82 million people globally. The first confirmed case in the United Arab Emirates (UAE)was reported on 29th January 2020. Current data suggests that children with COVID-19 have a mild disease course. There is lack of extensive published about infection among Arabian Gulf region. Methods This cross-sectional multicenter study included admitted between March 1st and June 15th, 2020 to three large hospitals Dubai,...
<h3></h3> Although pleural effusion is a recognised (if unusual) complication of pancreatitis in adults, it very rare children. We present the case nine year-old male patient, previously well,who presented after holiday Thailand with chronic back pain. Initial investigations were clear but he was admitted two weeks later massive right sided requiring repeated draining. Investigation showed no evidence infection or malignancy, had serum amylase level 2096 (normal <106) and 35,240. His...
<b>Objectives:</b> The positive impact of optimal nutritional status and increasing BMI on clinical outcome including lung function in cystic fibrosis is established.Do improve with gastrostomy insertion? Evidence so far has been ambiguous.The aim this study was to measure changes BMI,BMI z score (FEV1 percentile predicted FVC predicted) pre post CF patients.We further assessed the number days IV antibiotics required gastrostomy. <b>Methods:</b> Data 10340 patients obtained from UK trust...
Evidence has shown that omalizumab is highly effective for the treatment of severe allergic asthma inadequately controlled on step 5 BTS guideline. <b>OBJECTIVE:</b> To evaluate efficacy Omalizumab in carefully selected group children with aged 6 -18 years. <b>METHOD:</b> This a retrospective observational study 19 treated minimum 4 months between 2011 and 2015.Number exacerbations(requiring oral corticosteroids ≥3 days),unscheduled hospital visits,HDU/PICU admissions,inhaled corticosteroid...
<h3>Aim</h3> Main goal of this study was to examine the clinical characteristics chronic lung disease (CLD) among premature infants on home oxygen. <h3>Methods</h3> Medical records 28 oxygen (mean = 6.8±4.6 months) were examined retrospectively. All diagnosed with CLD. Data including demographic information, duration ventilation, and medication collected. <h3>Results</h3> eligible (17/28 (60%) are males 15/28 (53%) white Caucasians) born under 30 weeks gestation (Range from 23 29+6 weeks)....
<h3>Aim</h3> A four year retrospective review of safety and efficacy Palivizumab in the prophylaxis respiratory syncytial virus (RSV) high risk infants. <h3>Background</h3> RSV is leading viral pathogen responsible for hospitalization with lower tract infection infants previous study reported a 55% reduction related hospitalizations passive immunoprophylaxis Paluvizimab<sup>1</sup>. <h3>Methods</h3> all requiring between 2006 2010. Inclusion criteria included children under 2 years chronic...
<h3>Aim</h3> A four-year retrospective review of the safety and efficacy Palivizimab in prophylaxsis respiratory syncitial virus (RSV) high risk infants <h3>Background</h3> RSV is leading viral pathogen responsiible for hospitalisation with lower tract infection infants. It accounts 20,000 admissions /year United Kingdom. 90% are infected by 2 years age. previous randomised controlled study reported a 55% reduction RSV-related hospitalisations passive immunoprophylaxis human monoclonal...
<h3>Introduction</h3> Many factors might influence length of chest drainage (LOCD) when managing parapneumonic effusions/empyema including effusion size, septations, extent pneumonia, presence air leaks, pathogen virulence, fibrinolytic therapy with urokinase and local policies. UK guidelines recommend using the same fixed volumes for infants all children older than a year regardless size. This preliminary retrospective survey was undertaken to determine whether there may be signal suggest...
Background Coronavirus disease-2019 (COVID-19) has infected over 20 million people globally. The first confirmed case in the United Arab Emirates (UAE) was reported on 29th January 2020. To date there is no published data about COVID-19 infection among children Arabian region. Objective describe epidemiologic, clinical and laboratory characteristics of hospitalized with Dubai, UAE Methods A cross-sectional multicentre study admitted between March 1st June 15th, 2020 to three large hospitals...