A5052393431- Sperm and Testicular Function
- Reproductive Biology and Fertility
- Reproductive Health and Technologies
- Digital Holography and Microscopy
- Advanced X-ray Imaging Techniques
- Computational Drug Discovery Methods
- Innovative Microfluidic and Catalytic Techniques Innovation
- Optical measurement and interference techniques
- Reproductive biology and impacts on aquatic species
- Digital Imaging for Blood Diseases
- Near-Field Optical Microscopy
- Hepatitis C virus research
- Domain Adaptation and Few-Shot Learning
- AI in cancer detection
- Bee Products Chemical Analysis
University of Hyderabad
2016-2024
Manipal Academy of Higher Education
2011-2017
Kasturba Medical College, Manipal
2011-2017
Male reproductive function has recently attracted increasing attention due to reports on time-related decline in semen quality. Furthermore, regional differences the quality have also been reported.To investigate among large cohort of infertile individuals at a level, terms sperm concentration, total motility, morphology and incidence azoospermia over period 13 years.University infertility clinic Kasturba Hospital, Manipal which is tertiary healthcare centre serving general...
This paper presents a method for classifying zebrafish images captured before and after drug administration. Leveraging the power of transfer learning fine-tuning, approach effectively overcomes challenges limited datasets in biomedical imaging. By employing pre-trained convolutional neural network (CNN) as base model, allows us to utilize learned features from large-scale image datasets, significantly reducing training time computational resources. Fine-tuning specific layers model on our...
Objective:The aim of this experimental prospective study was to investigate the efficacy single and combination sperm wash methods for their ability isolate DNA intact spermatozoa.Material Methods: Sperm damage introduced by local testicular irradiation in male mice extent quantified comet assay.The spermatozoa were subjected (swim up or density gradient method) also a techniques.The integrity various sub-fractions techniques evaluated. Results:The amount damaged did not differ between...
We present results from non-interferometric quantitative phase imaging (QPI) for thickness estimation and morphological analysis of human spermatozoa. QPI along with algorithms image processing enable localization quantification subcellular structures spermatozoa, including the acrosomal, nuclear, mid-piece, tail regions. This approach based on transport intensity equation (TIE) using a simple brightfield microscope renders nanometric depth sensitivity, allowing precise structural resolution...
Most living cells are optically transparent which makes it difficult to visualize them under bright field microscopy. Use of contrast agents or markers and staining procedures often followed observe these cells. However, most toxic not applicable for live cell imaging. In the last decade, quantitative phase imaging has become an indispensable tool morphological characterization objects without any markers. this paper, we report noninterferometric sperm by solving transport intensity...
Unsymmetrical urea is a ubiquitous moiety in pharmaceuticals, providing linkage between pharmacophores. The assembly of an unsymmetrical bridge various therapeutic agents can be accomplished through several approaches. Conventional methods involving hazardous compounds such as phosgene and isolated isocyanates pose safety concerns; safe surrogate phosgene, namely CDI, popularly employed for the construction both symmetrical urea. While use CDI small-scale synthesis NCEs popular strategy,...