- Intensive Care Unit Cognitive Disorders
- Anesthesia and Neurotoxicity Research
- Anesthesia and Sedative Agents
- Obstructive Sleep Apnea Research
- Sleep and Wakefulness Research
- Neuroscience of respiration and sleep
- Cardiac, Anesthesia and Surgical Outcomes
Harvard University
2022-2024
Technical University of Munich
2021-2024
Katharinenhospital
2022-2024
Beth Israel Deaconess Medical Center
2022-2024
Klinikum rechts der Isar
2021-2024
Klinikum Stuttgart
2022-2024
Friedrich-Alexander-Universität Erlangen-Nürnberg
2018
Universitätsklinikum Erlangen
2018
BACKGROUND: Patients suffering from obstructive sleep apnea (OSA) experience chronic disturbances and desaturation, factors that have been associated with postoperative delirium can be aggravated after anesthesia for complex procedures. We investigated whether OSA is anesthesia, this association modified by procedural complexity. METHODS: Hospitalized patients ≥60 years who underwent general or sedation procedures of moderate-to-high complexity between 2009 2020 at a tertiary health care...
Abstract Background With increasing age older patients are at higher risk for cognitive decline after surgery. Even tailored anesthesia procedures in remain a high postoperative disorder. Additional stress derived from anxiety and itself can negatively impact outcomes. The objective of this study was to evaluate the general versus regional on disorder indicators perioperative elderly undergoing Methods In single center prospective between December 2014 November 2015, 46 aged 50 85 years...
The obstructive sleep apnea syndrome (OSAS) is characterized by temporary cerebral hypoxia which can cause cognitive dysfunction. On the other hand, induced neurocognitive deficits are detectable after general anesthesia. objective of this study was to evaluate impact a high risk OSAS on postoperative dysfunction intravenous In single center trial between June 2012 and 2013 43 patients aged 55 80 years with an estimated hospital stay at least 3 days undergoing surgery were enrolled. Patients...
The obstructive sleep apnea syndrome (OSAS) is characterized by intermittent cerebral hypoxia which can cause cognitive alterations. Likewise, induced neurocognitive deficits are detectable after general anesthesia using volatile anesthetics. objective of this study was to evaluate the association between a moderate high risk patients OSAS and postoperative dysfunction anesthesia.In single center prospective, observational May 2013 September 2013, 46 aged 55 80 years with an estimated...
Abstract Purpose Postoperative delirium (POD) in patients with obstructive sleep apnea (OSA) is associated increased mortality and healthcare costs. In this study, we investigated the association of OSA risk, serum biomarkers for central nervous ischemia (S100B NSE), POD. Methods After research ethics approval, completed STOP BANG assessment before undergoing elective surgery. Blood was drawn S100B NSE measurement, cognitive performance tested using Montreal Cognitive Assessment (MoCA) at...