- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Anesthesia and Sedative Agents
- Cardiac, Anesthesia and Surgical Outcomes
- Airway Management and Intubation Techniques
- Cardiac Arrest and Resuscitation
- Anesthesia and Pain Management
- Neonatal Respiratory Health Research
- Anesthesia and Neurotoxicity Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- SARS-CoV-2 and COVID-19 Research
- Hemodynamic Monitoring and Therapy
- Ion channel regulation and function
- Pain Mechanisms and Treatments
- Gastroesophageal reflux and treatments
- Atrial Fibrillation Management and Outcomes
- Gastric Cancer Management and Outcomes
- Photoreceptor and optogenetics research
- Nausea and vomiting management
- Bariatric Surgery and Outcomes
- Cannabis and Cannabinoid Research
- Sepsis Diagnosis and Treatment
- Long-Term Effects of COVID-19
- Vaccine Coverage and Hesitancy
- Artificial Intelligence in Healthcare and Education
Harvard University
2021-2025
Beth Israel Deaconess Medical Center
2021-2025
University of Jordan
2019-2025
Albert Einstein College of Medicine
2024-2025
Montefiore Medical Center
2024-2025
Heinrich Heine University Düsseldorf
2024
Düsseldorf University Hospital
2024
Royal Holloway University of London
2024
Pain and Rehabilitation Medicine
2024
Hadassah Medical Center
2022
The number of COVID-19 (Coronavirus Disease 2019) cases in Jordan is rising rapidly. A serious threat to the healthcare system appears on horizon. Our study aims evaluate preparedness Jordanian frontline doctors worsening scenario. It has a questionnaire-based cross-sectional structure. questionnaire was designed according knowledge about virus transmission and protective measures, adherence protection guidelines, psychological impacts affecting doctors. Institutional factors doctors’...
BACKGROUND: It is unclear whether intraoperative arterial hypotension associated with postoperative delirium. We hypothesized that within a range frequently observed in clinical practice increased odds of delirium after surgery. METHODS: Adult noncardiac surgical patients undergoing general anesthesia at 2 academic medical centers between 2005 and 2017 were included this retrospective cohort study. The primary exposure was hypotension, defined as the cumulative duration an mean pressure...
COVID-19 (coronavirus disease 2019) vaccines induce immunity through different mechanisms. The aim of this study is to compare the titers specific antibodies in subjects vaccinated with either Pfizer-BioNTech vaccine or Sinopharm vaccine. This prospective observational cohort included Jordanian adults two doses, 21 days apart, aforementioned vaccines. Titers were collected 6 weeks after administration second dose. Overall, 288 participants included, which 141 administered vaccine, while 147...
Mechanical power during ventilation estimates the energy delivered to respiratory system through integrating inspiratory pressures, tidal volume, and rate into a single value. It has been linked lung injury mortality in acute distress syndrome, but little evidence exists regarding whether concept relates patients with healthy lungs. This study hypothesized that higher mechanical is associated greater postoperative failure requiring reintubation undergoing general anesthesia. In this...
Vaccination is the most promising strategy to counter spread of Coronavirus Disease 2019 (COVID-19). Vaccine hesitancy a serious global phenomenon, and therefore aim this cross-sectional study was explore effect educational background, work field, social media on attitudes towards vaccination in Jordan. We compared between medical personnel who were direct contact with patients non-medical individuals at Jordan University Hospital terms demographics, knowledge about COVID-19 vaccines, rumors...
Previous studies linked a high intensity of ventilation, measured as mechanical power, to mortality in patients suffering from "classic" ARDS. By contrast, mechanically ventilated with diagnosis COVID-19 may present intact pulmonary mechanics while undergoing ventilation for longer periods time. We investigated whether an association between higher power and is modified by COVID-19.This retrospective study included critically ill, adult who were at least 24 h March 2020 December 2021...
Lung-protective mechanical ventilation strategies have been proven beneficial in the operating room (OR) and ICU. However, differential practices ventilator management persist, often resulting adjustments of parameters when transitioning patients from OR to
Background: Recruitment maneuvers are used in patients with ARDS to enhance oxygenation and lung mechanics. Heterogeneous chest-wall mechanics lead unpredictable transpulmonary pressures could impact recruitment maneuver success. Tailoring care based on individualized pressure might optimize recruitment, preventing overdistention. This study aimed identify the optimal for effective explore its association baseline characteristics. Methods: We performed post hoc analysis Esophageal Pressure...
Summary Reversing neuromuscular blockade with sugammadex can eliminate residual paralysis, which has been associated postoperative respiratory complications. There are equivocal data on whether reduces these when compared neostigmine. We investigated the association of choice reversal drug complications and advanced healthcare utilisation. included adult patients who underwent surgery received general anaesthesia or neostigmine at two academic networks between January 2016 June 2021. The...
Background The treatment of intraoperative hypotension with phenylephrine may impair cerebral perfusion through vasoconstriction, which has been linked to postoperative delirium. hypothesis was that administration phenylephrine, compared ephedrine, is associated higher odds Methods A total 103,094 hospitalized adults undergoing general anesthesia for noncardiac, non-neurosurgical procedures between 2008 and 2020 at two tertiary academic healthcare networks in Massachusetts were included this...
Background High numbers of violence incidents against physicians are reported annually in both developing and developed countries. In Jordan, studies conducted on healthcare workers involved small number showed higher percentages exposure when compared to other investigations from the Middle East. This is a large study aiming comprehensively analyze phenomenon physicians’ community optimize future strategies countering it. Methods The has cross sectional, questionnaire-based design. It...
Vaccines are considered the best approach for countering COVID-19 pandemic. In this study, we compared early side effects associated with vaccination Sinopharm and Pfizer–BioNTech vaccines. Participants of observational cohort were interviewed based on semi-structured telephone interviews, enquiries about that developed after each dose these Overall, 1004 participants enrolled, which 51.1% received vaccine 48.9% vaccine. After first dose, 46.3% had an adverse reaction, injection site pain...
OBJECTIVES: High mechanical power and driving pressure (ΔP) have been associated with postoperative respiratory failure (PRF) may be important parameters guiding ventilation. However, it remains unclear whether high ΔP merely reflect patients poor system mechanics at risk of PRF. We investigated the effect on PRF in cohorts after exact matching by patients’ baseline compliance. DESIGN: Hospital registry study. SETTING: Academic hospital New England. PATIENTS: Adult undergoing general...
Queuing theory is the mathematical study of waiting lines customers in a service system such as fuel stations, supermarket check-out counters, post offices, cafeteria, and banking halls. In queuing theory, model constructed so that important characteristics systems can be obtained measure performance. The obvious cost implications range from idle time spent when queue builds up, which results man-hour loss, to loss goodwill, may occur are dissatisfied with system. However, bid increase rate,...
Background: Community pharmacists (CPs) are pivotal in healthcare delivery; they the first point of contact for services and trusted by patients. Their role goes beyond dispensing medications to encompass emergency care management, health promotion, management chronic diseases. The review aimed explore strategies strengthen CPs global primary service provision. Methods: search followed a framework described Arksey O'Malley, subsequently expanded Levac et al.. An extensive relevant academic...
Perioperative opioid use has been associated with adverse clinical outcomes. Additionally, disposal carries significant costs, due to the waste of pharmaceutical products and time needed by skilled labor report waste. In this study, we aimed estimate costs predict factors opioid-associated intraoperative product waste, as well evaluate whether higher doses are increased risk postoperative We included 170,607 patients undergoing general anesthesia receiving fentanyl, hydromorphone, or...
Background: Racial differences in postoperative atrial fibrillation (POAF) and stroke rates following noncardiac surgery are not well understood may be influenced by varying betablocker prescription patterns. 1 Methods: This multicentric retrospective observational study included 205,886 adult patients without pre-existing who underwent non-cardiac between 2005 2021 at two tertiary care academic healthcare networks the Bronx, New York, Boston, Massachusetts. The population consisted of...
Abstract Background and Objectives Previous studies reported a predisposition to major adverse cardiovascular or cerebrovascular events (MACCE) in patients consuming cannabis, which might be exacerbated by interventional surgical procedures. This study investigated the association of nonmedical cannabis use with MACCE after procedures surgery. Methods 288,923 adult undergoing noncardiac surgery between 2008 2020 at tertiary academic hospital Massachusetts, United States, were included. The...
BACKGROUND: Nondepolarizing neuromuscular blocking agents (ND-NMBAs) are dose-dependently associated with residual paralysis, delayed recovery, and prolonged hospitalization, factors that can predispose patients to postoperative delirium. We hypothesized blockade is a higher risk of delirium after surgery, this be mitigated by administration reversal agents. METHODS: In total, 53,772 adult hospitalized aged ≥60 years who underwent general anesthesia for noncardiac, nonneurosurgical,...