- Cardiac, Anesthesia and Surgical Outcomes
- Airway Management and Intubation Techniques
- Anesthesia and Sedative Agents
- Hemodynamic Monitoring and Therapy
- Enhanced Recovery After Surgery
- Anesthesia and Neurotoxicity Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Tracheal and airway disorders
- Intracranial Aneurysms: Treatment and Complications
- Foreign Body Medical Cases
- COVID-19 and healthcare impacts
- Cancer and Skin Lesions
- Intraoperative Neuromonitoring and Anesthetic Effects
- Nausea and vomiting management
- Intensive Care Unit Cognitive Disorders
- Renal function and acid-base balance
- Meningioma and schwannoma management
- Tumors and Oncological Cases
- Diet and metabolism studies
- Electrolyte and hormonal disorders
- Healthcare cost, quality, practices
- Spinal Cord Injury Research
- Liver Disease and Transplantation
- Contact Dermatitis and Allergies
- Anesthesia and Pain Management
Beth Israel Deaconess Medical Center
2018-2023
Harvard University
2018-2023
Creative Commons
2022
National Patient Safety Foundation
2020
American Society of Anesthesiologists
2020
Duke University Hospital
1969-2018
Duke Medical Center
1969-2018
Mednax (United States)
2017
Medica (United States)
2017
Maidstone and Tunbridge Wells NHS Trust
2015
Intraoperative awareness in patients undergoing general anesthesia is an infrequent but well-described adverse outcome. The reported incidence of this phenomenon between 0.1% and 0.9%.With institutional review board approval, the authors reviewed continuous quality improvement data from 3 yr (2002-2004) at locations where physician group provided anesthesia. Board-certified anesthesiologists supervising certified registered nurse anesthetists care team model practice delivered all...
BACKGROUND: It is unclear whether intraoperative arterial hypotension associated with postoperative delirium. We hypothesized that within a range frequently observed in clinical practice increased odds of delirium after surgery. METHODS: Adult noncardiac surgical patients undergoing general anesthesia at 2 academic medical centers between 2005 and 2017 were included this retrospective cohort study. The primary exposure was hypotension, defined as the cumulative duration an mean pressure...
Clinical and morphologic features of seven T-cell lymphomas the large cell type are described. The tumors were grouped into those with irregular (3 cases) round regular nuclei (4 cases). In both groups, variation in size, numerous histiocytes vessels, many mitoses distinguishing features. only 1 case nucleus group was there relatively little size a paucity histiocytes. Abundant polyribosomes, long strands rough endoplasmic reticulum, lysosomal granules prominent electron microscopic groups...
CONSTANT, ERRIKOS M.D.; ROYER, JOHN R. POLLARD, RICHARD J. LARSEN, ROBERT D. POSCH, JOSEPH L. M.D. Author Information
When tracheal intubation is difficult or unachievable before surgery during an emergent resuscitation, this a critical safety event. Consensus algorithms and airway devices have been introduced in hopes of reducing such occurrences. However, evidence improved clinical practice related to their introduction lacking. Therefore, we selected large perioperative database spanning 2002 2015 look for changes annual rates failed intubation.Difficult (more than three attempts) (unsuccessful,...
1The Grace Hospital, Detroit, Michigan Division of Surgery, Section Colon and Rectal Surgery. Pathology.
BACKGROUND: Intraoperative cerebral blood flow is mainly determined by perfusion pressure and autoregulation of vasomotor tone. About 1% patients undergoing noncardiac surgery develop ischemic stroke. We hypothesized that intraoperative hypotension within a range frequently observed in clinical practice associated with an increased risk perioperative stroke 7 days after surgery. METHODS: Adult surgical general anesthesia at Beth Israel Deaconess Medical Center Massachusetts General Hospital...
Summary: Topiramate (TPM) is a novel antiepileptic medication (AED) with at least three mechanisms of action. A possible fourth mechanism, that carbonic anhydrase inhibitor, also may contribute to its properties. We report patient intractable epilepsy and normal renal function who developed anion gap metabolic acidosis, which worsened during elective surgery for temporal lobectomy. believe this side effect TPM can become clinically significant surgery, concomitant use another potentially the...
While continuation of β-blockers (BBs) perioperatively has become a national quality improvement measure, the relationship between BB withdrawal and mortality cardiovascular-related critical indicators not been studied in contemporary cohort patients undergoing noncardiac surgery.For this retrospective study, assurance database large community-based anesthesiology group practice was used to identify 410,288 surgical cases, 18 years age or older, who underwent elective emergent procedures...
To verify a safe location of the endotracheal tube (ETT), palpation ETT at sternal notch is time-honored technique: After anesthetic induction and confirmation orotracheal intubation, patient's head placed in neutral position. The withdrawn or advanced while gentle, repetitive pressure applied with fingers level suprasternal notch. Simultaneously, pilot balloon held other hand. When distends from notch, secured. We tested efficacy this technique men women who underwent general anesthesia....
Routine workflows were redesigned during the first surge of COVID-19 pandemic to standardize perioperative management patients and minimize risk viral exposure transmission staff members. Just-in-time (JIT), in situ simulation training was adopted implement urgent change, value which a public health crisis has not previously been explored.Implementation workflow changes setting accomplished through JIT, training, delivered over period 3 weeks participants from anesthesia, nursing, surgery,...
Objective: To describe the incidence of difficult and failed intubations in obstetric patients during a 6 year period monitored by quality assurance program together with American Society Anesthesiologists Physical Status (ASA PS) scores, obesity (body mass index >30 kg/m2).Methods: Following Institutional Review Board approval, data about who experienced unanticipated or from 2010 to 2015 was obtained database large, community-based anesthesiology group practice. The employs standardized...
Hypotensive transfusion reactions, which account for almost 3% of all are associated with patients treated angiotensin-converting enzyme inhibitors. The current hypothesis suggests that they caused by bradykinin-induced vasodilation in the absence allergic, hemolytic, or septic mechanisms. hypotension observed frequently is unresponsive to conventional therapy catecholamines. suggested intraoperative management includes cessation and washing red blood cells before replacement. We present a...
To verify a safe location of the endotracheal tube (ETT), palpation ETT at sternal notch is time-honored technique: After anesthetic induction and confirmation orotracheal intubation, patient's head placed in neutral position. The withdrawn or advanced while gentle, repetitive pressure applied with fingers level suprasternal notch. Simultaneously, pilot balloon held other hand. When distends from notch, secured. We tested efficacy this technique men women who underwent general anesthesia....
Volatile and intravenous anesthetics have substantial effects on physiological functions, notably influencing neurological function susceptibility to injury. Despite the importance of anesthetic approach, data its relative risks or benefits during surgical clipping endovascular treatments for unruptured intracranial aneurysms (UIAs) remains scant. We investigated whether using volatile alone in combination with propofol infusion yields superior outcomes following UIA obliteration....