A5002893015- Pneumonia and Respiratory Infections
- Respiratory viral infections research
- Bacterial Infections and Vaccines
- Streptococcal Infections and Treatments
- SARS-CoV-2 and COVID-19 Research
- Neonatal and Maternal Infections
- Influenza Virus Research Studies
- Orthopedic Infections and Treatments
- Hematological disorders and diagnostics
- Telemedicine and Telehealth Implementation
- Cerebrospinal fluid and hydrocephalus
- Toxin Mechanisms and Immunotoxins
- Sepsis Diagnosis and Treatment
- Nail Diseases and Treatments
- Parvovirus B19 Infection Studies
- Infectious Encephalopathies and Encephalitis
- Viral Infections and Outbreaks Research
- Peptidase Inhibition and Analysis
- Cystic Fibrosis Research Advances
- Long-Term Effects of COVID-19
- RNA regulation and disease
- Neonatal skin health care
- Infectious Diseases and Tuberculosis
- SARS-CoV-2 detection and testing
- Antibiotics Pharmacokinetics and Efficacy
Tokyo Metropolitan Children's Medical Center
2022-2025
Nagano Children's Hospital
2024
Office of Infectious Diseases
2024
Yokohama Rosai Hospital
2018-2021
Keio University
2021
Public Health England
2020
Japan Organization of Occupational Health and Safety
2018-2019
Abstract Background Parechovirus-A (PeV-A), especially PeV-A3, is a common cause of viral sepsis and encephalitis in neonates young infants (age < 4 months). The strict infection control measures non-pharmaceutical interventions the coronavirus disease 2019 (COVID-19) pandemic affected epidemiological profiles community-acquired diseases. However, effects on epidemiology PeV-A this age group are unknown. Methods This prospective multicenter observational study was conducted between...
Abstract Background Respiratory viruses can spread within healthcare facilities despite stringent infection prevention measures. Although healthcare-associated respiratory virus infections (HARVI) pose a significant risk to children, pediatric HARVI are understudied. The present study aimed evaluate the impact of on children following SARS-CoV-2 pandemic at tertiary children’s hospital. Methods This retrospective enrolled inpatients aged ≤18 years who were hospitalized Tokyo Metropolitan...
Abstract Background Although parainfluenza virus type 4 (PIV-4) typically causes mild respiratory illnesses in children, it can cause severe diseases occasionally. It is not known Whether viral load of PIV-4 could correlate with severity. This study aimed to assess the relationship between and disease’s severity children. Viral figure shows illness load.There was no correlation Methods A retrospective at Tokyo Metropolitan Children's Medical Center from April October 2023 screened...
Acute bacterial arthritis (ABA) is a serious, pediatric infection that can result in motor comorbidities. Normally, joint fluid white blood cell (WBC) count of 50,000 or more cells/mm 3 used to make presumptive diagnosis ABA. This study evaluated the utility WBC for diagnosing ABA confirmed by positive culture result.
Introduction. Recently, a Haemophilus influenzae clone with low susceptibility to quinolones emerged in paediatric patients Japan. Isolates of this survived for long time when exposed the therapeutic concentration quinolones, despite being classified as 'susceptible' under criteria Clinical and Laboratory Standards Institute. In present study, we report first outbreak 2018.Aim. Our aim was characterise an H. quinolones.Methodology. All isolates (n=62), collected at Japanese teaching hospital...
During influenza epidemics, Japanese clinicians routinely conduct rapid diagnostic tests (RIDTs) in patients with influenza-like illness, and positive test results are treated anti-influenza drugs within 48 h after the onset of illness. We assessed vaccine effectiveness (VE) inactivated (IIV) children (6 months–15 years old, N = 4243), using a test-negative case-control design based on RIDTs 2018/19 season. The VE against A(H1N1)pdm A(H3N2) was analyzed separately an RIDT kit specifically...
Acute coronavirus disease 2019 (COVID-19) is associated with chronic symptoms. These have been termed the "post COVID-19 condition." The data on this condition in children are still limited. We therefore aimed to elucidate characteristics of post condition.Children referred a long clinic were included at Tokyo Metropolitan Children's Medical Center between October 2021 and July 2022. Children another diagnosis those who failed meet criteria for excluded. Demographic clinical collected...
This review describes the epidemiology of group B Streptococcus (GBS) infection in infants Japan and discusses unresolved issues future perspectives. Guidelines for prevention vertical transmission were implemented 2008. The incidence early-onset disease has remained stable at approximately 0.10/1000 livebirths or less, which is lower than Europe North America. late-onset also low, but increased over last decade, with an estimated 0.29/1000 2020. National surveillance studies 2011-2015...
There is no report yet on the application of telemedicine in orthopedic practice Japan. With a focus patients with KOA, we investigated willingness to use by assessing factors such as patient's age, smartphone possession, hospital visiting time, and severity KOA.Data who regularly consulted surgeons at our institutions from April 2020 June were retrospectively analyzed using an electronic medical database. The diagnosed KOA according clinical radiological findings, Kellgren-Lawrence (KL)...
With the advent of multiplex polymerase chain reaction (PCR) using samples from a positive blood culture, time required to identify pathogen has significantly shortened few hours. It can help us select appropriate antimicrobial agents more quickly. The present study aimed assess impact PCR culture panel on administration agents.
To the Editors: Filobasidium magnum (formerly Cryptococcus magnus) is an environmental, yeast-like fungus generally regarded as having low pathogenicity.1 However, it has been reported in rare infections, including chronic periprosthetic shoulder arthritis,2 vaginitis3 and nasal colonization immunocompromised children.4 Here, we describe first case of catheter-related bloodstream infection caused by F. a 19-year-old female with Hirschsprung disease. The patient, history disease requiring...
Background: Hospital-related coronavirus disease 2019 (COVID-19) infection is of utmost concern among patients and health care workers. Expanding the use telemedicine may be required in daily outpatient practice; however, acceptance still low, especially older patients. In an orthopedic practice, no studies have investigated potential factors that can contribute to changes using telemedicine. Focusing on outpatients with knee osteoarthritis (KOA), we hypothesized a drastic surge number...
Abstract Background Septic arthritis is one of serious pediatric infections that could result motor comorbidities. Historically, joint fluid cell count 50,000 and over cells/mm3 has been used for presumptive diagnosis septic while awaiting culture result. Our aim study was to evaluate among patients confirmed with positive in children. Methods Patients were included at Tokyo Metropolitan Children's Medical Center from March 2010 2023. a pathogenic organism. negative without excluded....
Abstract Background Placement of ventriculoperitoneal (VP) shunt is an important treatment for pediatric hydrocephalus. Although prolonged perioperative antibiotic prophylaxis has theoretically no benefit in reducing device-associated infections, duration VP placement pediatrics not well established. As a part antimicrobial stewardship program (ASP), our ASP team recommended to stop sterile medical within 48 hours following surgery April 2017. Our aim this study was evaluate rate...