Toshinobu Kazui

ORCID: 0000-0003-1501-9639
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About
Contact & Profiles
Research Areas
  • Cardiac Valve Diseases and Treatments
  • Mechanical Circulatory Support Devices
  • Cardiac Structural Anomalies and Repair
  • Aortic Disease and Treatment Approaches
  • Infective Endocarditis Diagnosis and Management
  • Congenital Heart Disease Studies
  • Cardiac Arrest and Resuscitation
  • Cardiac and Coronary Surgery Techniques
  • Cardiovascular Function and Risk Factors
  • Aortic aneurysm repair treatments
  • Cardiac, Anesthesia and Surgical Outcomes
  • Atrial Fibrillation Management and Outcomes
  • Cardiac Arrhythmias and Treatments
  • Cardiac pacing and defibrillation studies
  • Transplantation: Methods and Outcomes
  • Cardiac Imaging and Diagnostics
  • Infectious Aortic and Vascular Conditions
  • Heparin-Induced Thrombocytopenia and Thrombosis
  • Cardiac tumors and thrombi
  • Venous Thromboembolism Diagnosis and Management
  • Coronary Artery Anomalies
  • Cardiac electrophysiology and arrhythmias
  • Heart Failure Treatment and Management
  • Orthopedic Infections and Treatments
  • Pulmonary Hypertension Research and Treatments

University of Arizona
2015-2024

Banner - University Medical Center Tucson
2015-2024

Banner Health
2022

Jewish Hospital
2012-2016

Barnes-Jewish Hospital
2012-2016

Cardiovascular Center Hokkaido Ohno Hospital
2006-2014

Washington University in St. Louis
2013-2014

St. Luke's International Hospital
2009-2011

Iwate Medical University
2002-2008

Hamamatsu University School of Medicine
2007

Right ventricular failure is a serious complication after left assist device placement. A 70-year-old male in decompensated heart with right the placement of device. single dual-lumen PROTEKDuo cannula was inserted percutaneously via internal jugular vein to draw blood from atrium and return into pulmonary artery using CentriMag system, by passing failing ventricle. The patient successfully weaned In comparison two-cannula conventional procedures, this ventrivular system improves...

10.1186/s13019-016-0515-y article EN cc-by Journal of Cardiothoracic Surgery 2016-08-04

Heparin-induced thrombocytopenia (HIT) is an immune reaction usually secondary to unfractionated heparin. Anticoagulation management critical in patients while on extracorporeal membrane oxygenation (ECMO) prevent thromboembolism and for the optimal functioning of circuit. We identified five with respiratory failure at our hospital managed ECMO last 2 years that were treated HIT. A brief clinical course their are discussed. also briefly review literature best evidence such patients.

10.1051/ject/201749054 article EN Journal of ExtraCorporeal Technology 2017-03-01

Objective Although the advent of ablation technology has simplified and shortened surgery for atrial fibrillation, only bipolar clamps have reliably been able to create transmural lesions on beating heart. Currently, there are no devices capable reproducibly creating long linear in right left atria needed perform a Cox-Maze procedure. This study evaluated performance novel suction-assisted radiofrequency device that uses both monopolar energy from an epicardial approach Methods Six domestic...

10.1097/imi.0b013e3182a77f2b article EN Innovations Technology and Techniques in Cardiothoracic and Vascular Surgery 2013-06-01

We report two cases of non-obstructive mesenteric ischemia (NOMI), a rare but potentially lethal complication after cardiovascular surgery, which was successfully managed. In both (a 74-year-old chronic hemodialysis patient who underwent emergency aortic valve replacement and coronary artery bypass graft (CABG), abdominal aneurysm operation), NOMI occurred early postoperatively (on day 8 22, respectively). They suffered from severe pain, confusion, metabolic acidosis. Contrast-enhanced...

10.5761/atcs.cr.10.01654 article EN cc-by-nc-nd Annals of Thoracic and Cardiovascular Surgery 2011-09-15

10.1016/j.jtcvs.2015.07.074 article EN publisher-specific-oa Journal of Thoracic and Cardiovascular Surgery 2015-07-29

Thrombosis within the membrane oxygenator (MO) during extracorporeal oxygenation (ECMO) can lead to sudden dysfunction with deleterious effects patient. The purpose of this study was identify predictors circuit exchange ECMO. This is a single-center, retrospective all patients who received ECMO at our institution from January 2010 December 2015. Changes in potential markers were compared on Day 3 vs. 0 before MO exchange. Of 150 ECMO, there 58 exchanges 35 patients. Mean duration 21.1...

10.1051/ject/201951061 article EN Journal of ExtraCorporeal Technology 2019-06-01

The pathogenicity of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has been attributed to its ability enter through the membrane-bound angiotensin-converting enzyme 2 (ACE2) receptor. Therefore, it heavily speculated that inhibitor (ACEI) or angiotensin receptor blocker (ARB) therapy may modulate SARS-CoV-2 infection. In this study, exposure human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) and endothelial cells (hECs) identified significant differences in protein...

10.1016/j.stemcr.2021.08.018 article EN cc-by-nc-nd Stem Cell Reports 2021-08-31

Current techniques to describe atrial function are limited by their load dependency and hence do not accurately reflect intrinsic mechanical properties. To assess the impact of fibrillation on function, combined pressure-volume relationships (PVR) measured conductance catheters were used evaluate right (RA) left (LA) atrium in 12 isoflurane-anesthetized pigs. Biatrial PVR recorded over a wide range volumes during transient caval occlusion at baseline sinus rhythm (SR), after onset rapid...

10.1152/ajpheart.01170.2011 article EN AJP Heart and Circulatory Physiology 2012-04-14

Maintaining mechanical circulatory support (MCS) device patients in a specified therapeutic range for anticoagulation remains challenging. Subtherapeutic international normalized ratios (INRs) occur frequently while on warfarin therapy. An effective anticoagulant bridge strategy may improve the care of these patients. This retrospective review MCS with subtherapeutic INRs compared an intravenous unfractionated heparin (UFH) subcutaneous enoxaparin or fondaparinux strategy. Native...

10.1097/mat.0000000000000747 article EN ASAIO Journal 2018-01-11

A retrospective study was performed to determine the appropriateness of aortic root remodeling with annuloplasty (m-Yacoub operation).A group 60 patients valve disease concomitant dilated or dissected ascending aorta, who underwent surgery between 1997 and 2003, were evaluated. Nineteen whose valves well preserved (mean age: 57.8+/-13.2 years) m-Yacoub operation without leaflet suspension. The average follow-up period 34.5+/-19.0 months. There no operative hospital deaths. Preoperatively, 16...

10.1253/circj.71.207 article EN Circulation Journal 2007-01-01

This study aimed at identifying the ideal right-to-left shunt-fraction to improve cardiac output (CO) and systemic perfusion in pulmonary arterial hypertension (PHT).Atrial septostomy (AS) has been a high-risk therapeutic option for symptomatic drug-refractory patients with PHT. Results have unpredictable due limited knowledge of optimal shunt-quantity.In nine dogs, an 8-mm shunt-prosthesis was inserted between superior vena cava (SVC) left atrium. With artery (PA) banding, mean (± SEM)...

10.1002/ccd.24458 article EN Catheterization and Cardiovascular Interventions 2012-04-18
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