A5089998159- Mycorrhizal Fungi and Plant Interactions
- Plant Pathogens and Fungal Diseases
- Fungal and yeast genetics research
- Evolution and Genetic Dynamics
- Plant and animal studies
- Genomics and Phylogenetic Studies
- Plant Disease Resistance and Genetics
- Lichen and fungal ecology
- Chromosomal and Genetic Variations
- Plant-Microbe Interactions and Immunity
- Yeasts and Rust Fungi Studies
- Insect and Arachnid Ecology and Behavior
- Fungal Biology and Applications
- Forest Insect Ecology and Management
- Evolutionary Game Theory and Cooperation
- Parasite Biology and Host Interactions
- Photosynthetic Processes and Mechanisms
- Protist diversity and phylogeny
- Plant and fungal interactions
- Genetic diversity and population structure
Wageningen University & Research
2009-2022
Uppsala University
2019-2022
Laboratory of Molecular Genetics
2015
The genomes of eukaryotes are full parasitic sequences known as transposable elements (TEs). Here, we report the discovery a putative giant tyrosine-recombinase-mobilized DNA transposon,
Abstract In multicellular organisms, there is a potential risk that cheating mutants gain access to the germline. Development from single-celled zygote resets relatedness among cells its maximum value each generation, which should accomplish segregation of non-cheaters and thereby protect cooperation. Here we provide crucial direct comparison between high- low-relatedness conditions test this hypothesis. We allow two variants fungus Neurospora crassa evolve, one with without ability form...
Meiotic drive is the preferential transmission of a particular allele during sexual reproduction. The phenomenon observed as spore killing in multiple fungi. In natural populations Podospora anserina , seven killer types ( Psk s) have been identified through classical genetic analyses. Here we show that Spok gene family underlies s. combination genes at different chromosomal locations defines and creates hierarchy within population. We identify two novel homologs located large (74–167 kbp)...
Abstract Allorecognition, the capacity to discriminate self from conspecific non-self, is a ubiquitous organismal feature typically governed by genes evolving under balancing selection. Here, we show that in fungus Podospora anserina , allorecognition loci controlling vegetative incompatibility ( het genes), define two reproductively isolated groups through pleiotropic effects on sexual compatibility. These emerge antagonistic interactions of unlinked het-r (encoding NOD-like receptor) and...
Allorecognition, the ability to distinguish "self" from "nonself" based on allelic differences at allorecognition loci, is common in all domains of life. Allorecognition restricts opportunities for social parasitism, and therefore crucial evolution cooperation. However, maintenance diversity provides a paradox. If costly relative cooperation, alleles will be favored. Thus, cost may reduce genetic variation upon which crucially relies, prediction now known as "Crozier's paradox." We establish...
The objective of this study was to explore the evolutionary history morphologically recognized filamentous ascomycete Neurospora tetrasperma, and reveal genetic reproductive relationships among its individuals populations. We applied both phylogenetic biological species recognition a collection strains representing geographic diversity N. tetrasperma. First, we were able confirm monophyletic origin Furthermore, found nine within morphospecies. When using traditional broad all investigated...
In filamentous fungi, allorecognition takes the form of heterokaryon incompatibility, a cell death reaction triggered when genetically distinct hyphae fuse. Heterokaryon incompatibility is controlled by specific loci termed het-loci. this article, we analyzed natural variation in one such fungal determinant, het-c locus ascomycete Podospora anserina. The determines an allogenic together with two unlinked het-d and het-e. Each allele incompatible subset het-e alleles. We variability at...
In the filamentous ascomycete Neurospora tetrasperma, a large (approx. 7 Mbp) region of suppressed recombination surrounds mating-type (mat) locus. While remainder genome is largely homoallelic, this recombinational suppression, extending over 1500 genes, associated with sequence divergence. Here, we used microarrays to examine how molecular phenotype gene expression level linked divergent region, and thus mating type. Culturing N. tetrasperma on agar media that induce sexual/female or...
The replication and segregation of multi-copy mitochondrial DNA (mtDNA) are not under strict control the nuclear DNA. Within-cell selection may thus favour variants with an intracellular selective advantage but a detrimental effect on cell fitness. High relatedness among mtDNA individual is predicted to disfavour such deleterious selfish genetic elements, experimental evidence for this hypothesis scarce. We studied opportunities suppressive in fungus Neurospora carrying mutator plasmid...
Abstract Some multicellular organisms can fuse because mergers potentially provide mutual benefits. However, experimental evolution in the fungus Neurospora crassa has demonstrated that free fusion of mycelia favours cheater lineages, but mechanism and evolutionary dynamics this exploitation are unknown. Here we show, paradoxically, all convergently evolved lineages have similar deficiencies. These mutants unable to initiate retain access wild-type with them. This asymmetry reduces...
Abstract Some multicellular organisms can fuse because mergers potentially provide mutual benefits. However, experimental evolution in the fungus Neurospora crassa has demonstrated that free fusion of mycelia favours cheater lineages, but mechanism and evolutionary dynamics dishonest exploitation are unknown. Here we show, paradoxically, all convergently evolved lineages have similar deficiencies. These mutants unable to initiate retain access wild-type with them. This asymmetry reduces...
The filamentous fungus Podospora anserina has been used as a model organism for more than 100 years and proved to be an invaluable resource in numerous areas of research. Throughout this period, P. embroiled number taxonomic controversies regarding the proper name under which it should called. most recent treatment proposed change important species Triangularia . results past changes indicate that broader research community is unlikely accept change, will lead nomenclatural instability...
Abstract The genomes of eukaryotes are full parasitic sequences known as transposable elements (TEs). Most TEs studied to date relatively small (50 – 12000 bp), but can contribute very large proportions genomes. Here we report the discovery a giant tyrosine-recombinase-mobilized DNA transposon, Enterprise , from model fungus Podospora anserina . Previously, described genomic feature called Spok block which is notable due presence meiotic drive genes gene family. ranges 110 kb 247 and be...
Abstract Meiotic drive is the preferential transmission of a particular allele at given locus during sexual reproduction. The phenomenon observed as spore killing in variety fungal lineages, including Podospora . In natural populations anserina , seven killers ( Psk s) have been identified through classical genetic analyses. Here we show that Spok gene family underlie killers. combination various genes different chromosomal locations defines and creates hierarchy within same population. We...
Meiotic drive is the preferential transmission of a particular allele during sexual reproduction. The phenomenon observed as spore killing in multiple fungi. In natural populations Podospora anserina, seven killer types (Psks) have been identified through classical genetic analyses. Here we show that Spok gene-family underlies Psks. combination genes at different chromosomal locations defines and creates hierarchy within same population. We identify two novel homologs located large (74-167...
Abstract S6.3 Fungal adaptation and evolution, September 22, 2022, 4:45 PM - 6:15 A total of 12 replicate populations initiated with a laboratory strain the ascomycete fungus Aspergillus nidulans evolved on synthetic minimal glucose agar medium for 1 year, using weekly transfers 1% produced asexual spores to fresh medium. This short-term evolution experiment (ASEX) was designed understand how filamentous fungi adapt growth limited carbon in spatially structured environment. We observed no...