A5056579654- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Orthopaedic implants and arthroplasty
- COVID-19 epidemiological studies
- Single-cell and spatial transcriptomics
- Electrospun Nanofibers in Biomedical Applications
- Tissue Engineering and Regenerative Medicine
- Dermatological and COVID-19 studies
- Pregnancy and preeclampsia studies
- Immune cells in cancer
- Iron Metabolism and Disorders
- Immune Response and Inflammation
- Hemoglobinopathies and Related Disorders
National Institute of Biomedical Imaging and Bioengineering
2022-2024
National Institutes of Health
2022-2024
The Wallace H. Coulter Department of Biomedical Engineering
2020
Georgia Institute of Technology
2020
ABSTRACT Due to a combination of asymptomatic or undiagnosed infections, the proportion United States population infected with SARS-CoV-2 was unclear from beginning pandemic. We previously established platform screen for positivity across representative US population, which we reported that almost 17 million Americans were estimated have had undocumented infections in Spring 2020. Since then, vaccine rollout and prevalence different variants further altered seropositivity trends within...
Immune responses to biomedical implants, wound healing, and diseased tissues often involve collagen deposition by fibroblasts other stromal cells. Dysregulated can lead complications such as biomaterial fibrosis, cardiac desmoplasia, liver pulmonary which ultimately result in losses of organ function or failure implants. Current vitro methods induce include growing the cells under macromolecular crowding conditions on fibronectin-coated surfaces. However, majority these have been...
The rat model is an important resource in biomedical research due to its similarities the human immune system and use for functional studies. However, because of preponderance mouse models foundational mechanistic immunological studies, there a relative lack diverse, commercially available flow cytometry antibodies profiling model. Available are often conjugated common fluorophores with similar peak emission wavelengths, making them hard distinguish on conventional cytometers restricting...
Abstract Dynamic pathogen exposure may impact the immunological response to SARS‐CoV‐2 (SCV2). One potential explanation for lack of severe SCV2‐related morbidity and mortality in Southeast Asia is prior related betacoronaviruses. Recent discoveries betacoronaviruses from horseshoe bats ( Rhinolophus sinicus ) Thailand, Laos, Cambodia suggest bat‐to‐human spillover exposures region. In this work, serum antibodies protein constructs SCV2 a representative bat coronavirus isolated (RshSTT182)...