- Opioid Use Disorder Treatment
- Prenatal Substance Exposure Effects
- Assisted Reproductive Technology and Twin Pregnancy
- Substance Abuse Treatment and Outcomes
- Prenatal Screening and Diagnostics
- Poisoning and overdose treatments
- Reproductive Health and Technologies
- Cardiac Arrest and Resuscitation
- HIV, Drug Use, Sexual Risk
- Pain Management and Opioid Use
- Pregnancy and preeclampsia studies
- Maternal Mental Health During Pregnancy and Postpartum
- Health disparities and outcomes
- Census and Population Estimation
- Health Policy Implementation Science
- Demographic Trends and Gender Preferences
- Food Security and Health in Diverse Populations
- Public Health Policies and Education
- Data-Driven Disease Surveillance
- Forensic Toxicology and Drug Analysis
- Pharmaceutical Practices and Patient Outcomes
- Patient Satisfaction in Healthcare
- Anesthesia and Pain Management
- Homelessness and Social Issues
- Emergency and Acute Care Studies
Massachusetts Department of Public Health
2016-2025
Commonwealth of Massachusetts
2021-2024
Quality and Reliability (Greece)
2023
Boston University
2018-2021
University of Massachusetts Chan Medical School
2018
Boston Medical Center
2018
National Center for Chronic Disease Prevention and Health Promotion
2016
Centers for Disease Control and Prevention
2016
Boston Children's Hospital
2015
Opioid overdose survivors have an increased risk for death. Whether use of medications opioid disorder (MOUD) after is associated with mortality not known.
OBJECTIVE: To estimate fatal and nonfatal opioid overdose events in pregnant postpartum women Massachusetts, comparing rates individuals receiving not pharmacotherapy for use disorder (OUD). METHODS: We conducted a population-based retrospective cohort study using linked administrative vital statistics databases Massachusetts to identify with evidence of OUD who delivered liveborn neonate 2012–2014. described maternal sociodemographic, medical, substance characteristics, computed the year...
<h3>Importance</h3> Racial and ethnic disparities persist across key health substance use treatment outcomes for mothers infants. The of medications, such as methadone or buprenorphine, the opioid disorder (OUD) has been associated with improvements in infants; however, only half all pregnant women OUD receive these medications. extent to which maternal race ethnicity is medication treat OUD, duration type used during pregnancy are unknown. <h3>Objective</h3> To examine medications year...
Background Few studies have described the neuropsychological outcomes and frequency of structural brain or genetic abnormalities in adolescents with single ventricle who underwent Fontan procedure. Methods Results In a cross‐sectional, single‐center study, we enrolled 156 subjects ventricle, mean age 14.5±2.9 years, had undergone Scores entire cohort on standard battery tests were compared those normative populations to group 111 locally recruited healthy adolescents. They also magnetic...
To estimate the annual prevalence of opioid use disorder (OUD) in Massachusetts from 2011 to 2015.We performed a multisample stratified capture-recapture analysis OUD Massachusetts. Individuals identified 6 administrative databases for 2012 and 7 2013 2015 were linked at individual level included analysis. by age group, sex, county residence.The among people aged 11 years or older was 2.72% 2.87% 2012. Between 2015, increased 3.87% 4.60%. The greatest increase observed those youngest group...
Opioid overdose deaths remain high in the U.S. Despite having effective interventions to prevent deaths, there are numerous barriers that impede their adoption. The primary aim of HEALing Communities Study (HCS) is determine impact an intervention consisting community-engaged, data-driven selection, and implementation integrated set evidence-based practices (EBPs) on reducing opioid deaths.The HCS a four year multi-site, parallel-group, cluster randomized wait-list controlled trial. (n = 67)...
Use of assisted reproductive technology (ART) has been associated with increased risks for birth defects. Variations in defect according to type ART procedure have noted, but findings are inconsistent.To examine the prevalence defects among liveborn infants conceived and without evaluate certain procedures ART-conceived infants.Used linked surveillance, certificates, registry data 3 states (Florida, Massachusetts, Michigan). Methods ascertaining cases varied by state. Resident live births...
<h3>Importance</h3> Although hospitalizations for injection drug use–associated infective endocarditis (IDU-IE) have increased during the opioid crisis, utilization of and mortality associated with receipt medication use disorder (MOUD) after discharge from hospital among patients IDU-IE are unknown. <h3>Objective</h3> To assess proportion receiving MOUD hospitalization association mortality. <h3>Design, Setting, Participants</h3> This retrospective cohort study used a population registry...
ABSTRACT Background and Aims Benzodiazepines are commonly prescribed to patients with opioid use disorder receiving buprenorphine treatment, yet may increase overdose risk. However, benzodiazepines improve retention in care by reducing discontinuation thus prevent relapse illicit use. We aimed test the association between benzodiazepine prescription fatal overdose, non‐fatal all‐cause mortality discontinuation. Design Setting This was a retrospective cohort study using five individually...
Objectives To examine the effect of age on likelihood PIP opioids and adverse outcomes. Design Retrospective cohort study. Setting Data from multiple state agencies in Massachusetts 2011 to 2015. Participants Adult residents (N=3,078,163) who received at least one prescription opioid during study period; approximately half (1,589,365) aged 50 older. Measurements We measured exposure 5 types PIP: high‐dose opioids, coprescription with benzodiazepines, prescribers, pharmacies, continuous...
Opioid overdose deaths quintupled in Massachusetts between 2000 and 2016. Potentially inappropriate opioid prescribing practices (PIP) are associated with increases overdoses. The purpose of this study was to conduct spatial epidemiological analyses novel comprehensively linked data identify PIP hotspots.Sixteen administrative datasets, including prescription monitoring, medical claims, vital statistics, examiner data, covering >98% residents 2011-2015, were 2017 better investigate the...
Opioid-related overdose is increasingly linked to pregnancy-associated deaths, but factors associated with postpartum are unknown. We aimed estimate the strength of association between maternal and infant characteristics opioid-related overdose.Retrospective cohort study using a linked, population-level data set.Massachusetts, United States.Among women who delivered live infants in Massachusetts, USA 2012 2014, diagnosis OUD, prior non-fatal overdose, NAS high unscheduled health-care...
Abstract Background and aim Medically managed opioid withdrawal (detox) can increase the risk of subsequent overdose. We assessed association between mortality following detox receipt medications for use disorder (MOUD) residential treatment after detox. Design Cohort study generated from individually linked public health data sets. Setting Massachusetts, USA. Participants A total 30 681 patients with 61 819 episodes 2012 2014. Measurements Treatment categories included no post‐detox...
As overdoses continue to increase worldwide, accurate estimates are needed understand the size of population at risk and address health disparities. Capture-recapture methods may be used in place direct estimation nearly any geographic level (e.g., city, state, country) estimate with opioid use disorder (OUD). We performed a multi-sample capture-recapture analysis persons aged 18-64 years prevalence OUD Massachusetts from 2014 2020, stratified by sex race/ethnicity.