Zhenrui Zhao

ORCID: 0000-0003-1510-9263
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About
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Research Areas
  • Plant and fungal interactions
  • Mycorrhizal Fungi and Plant Interactions
  • Fungal Biology and Applications
  • Nerve injury and regeneration
  • Plant Diversity and Evolution
  • RNA modifications and cancer
  • Paleontology and Stratigraphy of Fossils
  • Cancer Immunotherapy and Biomarkers
  • Inflammatory mediators and NSAID effects
  • Bone Tissue Engineering Materials
  • Osteoarthritis Treatment and Mechanisms
  • Entomopathogenic Microorganisms in Pest Control
  • Spine and Intervertebral Disc Pathology
  • Spinal Cord Injury Research
  • Plant Surface Properties and Treatments
  • Anesthesia and Pain Management
  • Immunotherapy and Immune Responses
  • Wound Healing and Treatments
  • Shoulder Injury and Treatment
  • Plant and Fungal Species Descriptions
  • Cellular Mechanics and Interactions
  • Chemical synthesis and alkaloids
  • 3D Printing in Biomedical Research
  • Synthesis of heterocyclic compounds
  • Pesticide and Herbicide Environmental Studies

Lanzhou University
2016-2025

First Hospital of Lanzhou University
2022

Ministry of Agriculture and Rural Affairs
2021-2022

Wuhan University of Science and Technology
2020

North Sichuan Medical University
2020

Abstract Endophytes generally increase antioxidant contents of plants subjected to environmental stresses. However, the mechanisms by which endophytes alter accumulation antioxidants in plant tissues are not entirely clear. We hypothesized that, stress situations, would simultaneously reduce oxidative damage and that be a consequence endophyte ability regulate expression genes. investigated effects fungal Epichloë gansuensis (C.J. Li & Nan) on damage, contents, representative genes...

10.1007/s00248-024-02391-2 article EN cc-by Microbial Ecology 2024-05-17

The present study was designed to explore the effects of endophyte Epichloë gansuensis on gene expression related plant hormone biosynthesis and response pathways content salicylic acid (SA) jasmonic (JA) hormones Achnatherum inebrians, under different moisture conditions. Through a pot experiment transcriptome analysis, we found total 51 differentially expressed genes (DEGs) pathways, including 12 auxin genes, 8 cytokinin (CTK) 3 gibberellin (GA) 7 abscisic (ABA) ethylene (ET) JA 4 SA...

10.3390/jof7080640 article EN cc-by Journal of Fungi 2021-08-06

In bone tissue engineering, biological scaffolds are designed with structural and functional properties that closely resemble the extracellular environment, aiming to establish a microenvironment conducive osteogenesis. Macrophages hold significant potential for promoting osteogenesis modulating behavior of tumor cells. Multiple coculture experiments macrophages osteoblasts have demonstrated macrophage polarization significantly impacts Therefore, exploring biomaterials can modulate holds...

10.1021/acsbiomaterials.4c00589 article EN ACS Biomaterials Science & Engineering 2024-08-28

Photosynthesis is essential for the growth of all green plants, and presence an Epichloë endophyte enhances photosynthesis Achnatherum inebrians (drunken horse grass, DHG), including when it under attack by fungal pathogens. However, few studies have examined mechanism increased photosynthetic activity at molecular level A. pathogen stress. The present study investigated effects on net rate, intercellular CO2 concentration, stomatal conductance, transpiration rate DHG plants a Blumeria...

10.3390/jof8111201 article EN cc-by Journal of Fungi 2022-11-14

The cuticular wax serves as the outermost hydrophobic barrier of plants against nonstomatal water loss and various environmental stresses. An objective this study was to investigate contribution mutualistic fungal endophyte Epichloë gansuensis leaf Achnatherum inebrians under different soil moisture availability. Through a pot experiment gas chromatography-mass spectrometry (GC-MS) analysis, our results indicated that hydrocarbons were dominant components wax, proportion alcohols, aldehydes,...

10.3390/jof8070725 article EN cc-by Journal of Fungi 2022-07-12

Abstract This study aimed to evaluate the analgesic effect of magnesium sulfate combined with a levobupivacaine periarticular cocktail in early postoperative period after total knee arthroplasty (TKA). A 60 patients who underwent primary unilateral TKA our department from March 2018 May 2019 were prospectively selected and randomly divided into trial group (30 20 mL 250 mg + 50 triamcinolone 25 0.9% normal saline) control saline). Visual analog scale (VAS) scores at 6, 12, 24, 48, 72 hours...

10.1055/s-0040-1710364 article EN The Journal of Knee Surgery 2020-05-20

As a heterogeneous and aggressive disease, osteosarcoma (OS) faces great challenges to prognosis individualized treatment. Hence, we explore the role of immune-related genes in predicting responsiveness immunotherapy targeted therapies patients with OS based on immunological landscape osteosarcoma. Based database Therapeutical Applicable Research Generate Effective Treatments (TARGET), single-sample gene set enrichment analysis (ssGSEA) was used obtain scores 29 immune characteristics. A...

10.3389/fmolb.2021.783915 article EN cc-by Frontiers in Molecular Biosciences 2022-01-20

Photosynthesis is essential for the growth of all green plants, and presence Epichloë endophyte enhances photosynthesis Achnatherum inebrians (drunken horse grass, DHG), including under attack by fungal pathogens. However, few studies have examined mechanism increased photosynthetic activity at molecular level A. when pathogen stress. The present study investigated effects on net rate, intercellular CO 2 concentration, stomatal conductance, transpiration rate DHG plants Blumeria graminis...

10.2139/ssrn.4202048 article EN SSRN Electronic Journal 2022-01-01

Cuticular wax plays a critical role as plant protectant against various environmental stresses. We predicted that the presence of mutualistic fungal endophyte Epichloë gansuensis in Achnatherum inebrians would change both composition leaf cuticular plants aged during growing season and gene expression levels associated with biosynthesis pathway. Endophyte-infected (EI) endophyte-free (EF) A. were established for four-month pot experiment. In agreement our prediction, E. can at different...

10.3390/agriculture12081154 article EN cc-by Agriculture 2022-08-04

Spinal cord injury (SCI) is a spinal nerve dysfunction secondary to trauma. Until now, still no appropriate drug with unclear etiology. Therefore, it develop effective SCI treatment methods. Herein, we intended detect the impact of miR-129-5p in After establishment mouse model, animals received intrathecal injection agomir-miR-129-5p or normal saline. Then, miR-129-5p’s effect was evaluated by assessing motor function, tissue edema, apoptosis and inflammation mice upon treatments potential...

10.1166/jbt.2023.3197 article EN Journal of Biomaterials and Tissue Engineering 2023-01-01
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