A5005498425- Nutrition and Health in Aging
- Clinical Nutrition and Gastroenterology
- HIV-related health complications and treatments
- Frailty in Older Adults
- Child Nutrition and Feeding Issues
- HIV Research and Treatment
- HIV/AIDS drug development and treatment
- Body Composition Measurement Techniques
- Cancer survivorship and care
- Dietetics, Nutrition, and Education
- Child Nutrition and Water Access
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Childhood Cancer Survivors' Quality of Life
- Obesity, Physical Activity, Diet
- Nutritional Studies and Diet
- Cerebral Palsy and Movement Disorders
- Obesity and Health Practices
- Effects of Radiation Exposure
- Folate and B Vitamins Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cancer Diagnosis and Treatment
- Stoma care and complications
- Fibromyalgia and Chronic Fatigue Syndrome Research
- HIV/AIDS Research and Interventions
- Physical Activity and Health
Cooper University Health Care
2025
King's College London
2014-2025
Cooper Medical School of Rowan University
2025
Newcastle University
2017
Hull York Medical School
2017
Newcastle Hospitals - Campus for Ageing and Vitality
2017
University of Newcastle Australia
2017
University of Hull
2017
London School of Economics and Political Science
2017
MRC Biostatistics Unit
2017
Increased expenditure of energy at rest has been considered a contributing factor to the negative balance and weight loss that occur in patients with human immunodeficiency virus (HIV) infection. However, true determinant is not resting but total expenditure. We sought determine contribution changes HIV-associated wasting.
Dramatic global increases in future numbers of people with dementia have been predicted. No multicentre population-based study powered to detect changes over time has reported incidence. MRC Cognitive Function and Ageing Study (CFAS) undertook baseline interviews populations aged 65+ years England Wales (1989-1994). Three areas (CFAS I) were selected for new sampling two decades later (2008-2011) same geographical boundaries, approach methods II). At 2 CFAS I interviewed 5,156 (76% response)...
•This ESMO Clinical Practice Guideline provides key recommendations for managing cancer-related cachexia.•It covers screening, assessment and multimodal management of cancer cachexia.•All were compiled by a multidisciplinary group experts.•Recommendations are based on available scientific data the author's expert opinion.
Little is known about how the proportions of dependency states have changed between generational cohorts older people. We aimed to estimate years lived in different at age 65 1991 and 2011, new projections future demand for care.In this population-based study, we compared two Cognitive Function Ageing Studies (CFAS I CFAS II) people (aged ≥65 years) who were permanently registered with a general practice three defined geographical areas (Cambridgeshire, Newcastle, Nottingham; UK). These...
Abstract Background: Weight loss in patients with cancer is common and associated a poorer survival quality of life. Benefits from nutritional interventions are unclear. The present study assessed the effect dietary advice and/or oral supplements on survival, endpoints life weight receiving palliative chemotherapy for gastrointestinal non‐small cell lung cancers or mesothelioma. Methods: Participants were randomly assigned to receive no intervention, advice, supplement plus before start...
Malnutrition in patients with cancer is common and an adverse prognostic indicator. A questionnaire answered by 357 (72%) UK specialist oncological trainees suggests that they lack the ability to identify factors place at risk from malnutrition. Major barriers effective nutritional practice included of guidelines, knowledge time.
Background: The mechanisms by which dyslipidemia and lipoatrophy develop during antiretroviral therapy are not clear. No treatment of is currently established. Methods: This was an open-label randomized study HIV-positive individuals on a first-line containing stavudine (d4T) with either protease inhibitor (PI) or nonnucleoside reverse transcriptase (NNRTI) hypercholesterolemia (defined as total cholesterol >5.2 mmol/L >180 mg/dL) and/or viral load <50 copies/mL. Patients switched d4T to...
Background Therapy with a HIV protease inhibitor is associated elevations in cholesterol and triglycerides. HMG-CoA reductase inhibitors (`statins') are the established therapy for persons primary hypercholesterolaemia. Because of drug interactions, pravastatin may represent preferred choice those taking inhibitors. Design A randomized, open-label comparative 24 week trial dietary advice alone or 31 male patients on inhibitor-based regimens greater than 12 weeks viral load < 500 copies/ml >...
We test the hypothesis that human immunodeficiency virus (HIV)-related weight loss is accompanied by inappropriately large losses of fat-free mass (FFM). Our secondary aims were to examine whether FFM increases during gain and compare several techniques for measuring change. was measured at intervals averaging 5 months in 21 AIDS patients means skinfold thickness (SF), dual-energy x-ray absorptiometry (DEXA), total body water (TBW), bioelectrical impedance using equation manufacturer...
This study examines small intestinal absorption-permeability, inflammation and ileal structure function in HIV-positive male homosexuals.Thirty HIV-seropositive homosexuals at various stages of disease underwent absorption permeability 111indium leukocyte studies (for quantification inflammation). Twenty-six men with AIDS had a dual radioisotopic test (whole body retention tauro 23-[75Se]-selena 25-homocholic acid 58cobalt-labelled cyanocobalamine), 17 ileocolonoscopy terminal biopsy.Well,...