Abstract Objectives Pain affects about one in every five persons and is considered a major global health burden. Hyphaene thebaica (Arecaceae), medicinal plant used Cameroon, fruit pulp are macerated orally administered traditional medicine to treat various ailments, including hypertension, pain, inflammation. This study aimed evaluate the pain-killing effect of extracts H. mice. Methods Aqueous (AEHT) methanol (MEHT) were prepared from , followed by qualitative phytochemical analysis. The...

Botanicals have shown promise in mitigating antibiotic resistance bacteria. This study examined the efficacy of methanolic extracts from two food plants ( Nephelium lappaceum and Hyphaene thebaica ), alone combination with antibiotics, against critical class priority bacteria, including multi-drug resistant (MDR) strains clinical isolates Staphylococcus aureus , Klebsiella pneumoniae Pseudomonas aeruginosa Enterobacter aerogenes Escherichia coli . The herbals underwent testing using a...

<title>Abstract</title> <bold>Background: </bold>Gastric ulcers are a common gastrointestinal disorder for which there is need to search better prevention method or treatment options. Accordingly, the aim of this study was assess protective effect combination <italic>Psidium guajava</italic> and <italic>Aloe vera</italic> extracts against ethanol-induced gastric in rats. <bold>Methodology: </bold>The ulcer induced rats using one oral dose absolute ethanol (5mL/kg body weight). A <italic>P....

Background: Gastric ulcers are a common gastrointestinal disorder for which there is need to search better prevention method or treatment options. Accordingly, this study aimed assess the protective effect of combination Psidium guajava and Aloe vera extracts against ethanol-induced gastric in rats. Methods: The ulcer was induced rats using one oral dose absolute ethanol (5 mL/kg body weight (b.w)). A P. A. at doses 125, 250 500 mg/kg b.w omeprazole 20 were given by gavage daily 21 days...

Abstract Background Nauclea pobeguinii is a plant species found in the centre region of Cameroon. The stem bark this traditionally used to ease pain and cure inflammation. Method This study was undertaken evaluate effects doses 150 300 mg/kg aqueous methanolic extracts from on acute pain, chronic inflammation induced by formalin arthritis zymosan A rats. Oxidative stress parameters such as catalase, malondialdehyde nitric oxide were measured rats subjected standard diclofenac at 5 mg/kg....

Entada africana (Mimosaceae) was reported to have analgesic and antioxidant properties. The present study is aimed at investigating the effects of root aqueous extract (EA) on an experimental model endometriosis. performed in rats orally treated with EA doses 127.5, 255, 510 mg/kg. Microgynon® 30 served as reference substance. Estradiol valerate oxytocin were used induce dysmenorrhea. Endometrial implant levels catalase malondialdehyde (MDA) allowed estimating tissue oxidative status....

Objective: To explore anti-hyperalgesic properties of methanol extract Piptadeniastrum africanum stem bark (PAME) and it possible action mechanism. Methods: PAME was tested on carrageenan induced hyperalgesia using plantar test (thermal) analgesymeter (mechanical) in rats, prostaglandin E2 (PGE2) mechanical vincristine neuropathic pain rat, both with analgesymeter. Modulators NO/ cGMP/K+ channel pathway endogenous opioids receptor antagonists and/or agonists were used to determine the...

This study investigated the effect of spirulina ethanolic extract (SEE) on quality ram semen during low-temperature liquid storage and relationship between sperm features. Ejaculates were collected from five Djallonké rams, pooled, extended with Tris-egg yolk (TEY) enriched 0 (control), 20 (SEE20), 40 (SEE40), 80 µg/mL (SEE80) SEE to reach concentration 200×106 spz/mL, stored at 4 °C for 72 h. Extended samples assessed total motility, progressive motion characteristics, viability, membrane...

Background Petersianthus macrocarpus (P. Beauv.) Liben (Lecythidaceae) is a plant used in Cameroonian folk medicine to cure ailments such as inflammation and pain. Previous work showed that aqueous (AEPM) methanol (MEPM) extracts from the stem bark of P. possess acute analgesic activities. The present study evaluates whether same could inhibit persistent hyperalgesia induced by complete Freund's adjuvant (CFA) rats. Methods Inflammatory pain was intraplantar injection CFA into left hind paw...

Background Boerhavia coccinea (Nyctaginaceae) is an herbaceous plant used for the treatment of pain. The aim this study was to evaluate antinociceptive and anti-inflammatory activities aqueous (AEBC) ethanol (EEBC) extracts as well major fractions (F1, F2 F3) from EEBC. Methods effect evaluated using formalin test. AEBC, EEBC F1 were selected further acutely (24 h) chronically (16 days) in Complete Freund's Adjuvant (CFA)-induced persistent inflammatory pain their antihyperalgesic effects....

Purpose: This work assesses the antiulcerogenic and antiulcer properties of aqueous extract Pittosporum mannii shows at what dosage this plant would not be any danger to patient.&#x0D; Methodology: The its bark, orally administered doses 35, 75, 150 300mg/kg, has been experimented on acute (HCl/EtOH (150mM HCl in 60% ethanol); ligature pylorus) chronic ulcers (acetic acid; 0.05 ml 30% acetic acid) induced rats.&#x0D; Findings: results from these experiments show that: barks possesses...