A5104883744- Renal Diseases and Glomerulopathies
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Mesenchymal stem cell research
- Cerebral Palsy and Movement Disorders
- Vasculitis and related conditions
- Glioma Diagnosis and Treatment
- Spinal Cord Injury Research
- Autoimmune Bullous Skin Diseases
- Cell Adhesion Molecules Research
- Pituitary Gland Disorders and Treatments
- Peripheral Neuropathies and Disorders
- Dermatological and COVID-19 studies
- Neurogenesis and neuroplasticity mechanisms
- Fetal and Pediatric Neurological Disorders
- Multiple Myeloma Research and Treatments
- Drug Transport and Resistance Mechanisms
- Parathyroid Disorders and Treatments
- Meningioma and schwannoma management
- Muscle and Compartmental Disorders
- Advances in Oncology and Radiotherapy
- Traumatic Ocular and Foreign Body Injuries
- Traumatic Brain Injury and Neurovascular Disturbances
- Stroke Rehabilitation and Recovery
- Abdominal Trauma and Injuries
- Healthcare Systems and Challenges
Yashoda Hospital
2023
Lokmanya Tilak Municipal General Hospital and Lokmanya Tilak Municipal Medical College
2006-2023
Neurogen Brain & Spine Institute
2010-2021
Post Graduate Institute of Medical Education and Research
2016
All India Institute of Medical Sciences
2014
All India Institute of Medical Sciences Bhopal
2014
CSIR National Physical Laboratory of India
2014
All India Institute of Medical Sciences Raipur
2014
Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital
2006
There was much progress in the field of Neurorestoratology year 2022. It included highlighting advances understanding pathogenesis neurological diseases, neurorestorative mechanisms, and clinical treatments as compiled 2022 yearbook Neurorestoratology. is still controversy about whether amyloid β-protein tau protein deposition are reasons for or results Alzheimer's disease (AD) pathology. The fabricated images important key articles that speculated on AD were found. Cholinergic deficiency...
Spinal cord injury (SCI) is catastrophic damage for patients, their family, and society. Researchers clinicians have been trying to find neurorestorative methods recover injured functions structures. Cell therapy one of the effective therapeutic strategies SCI. And it can partially restore neurological functions, which are once thought as permanent deficits. Currently, cells being used therapeutically in clinic include olfactory ensheathing (OECs), mononuclear (MNCs), mesenchymal stromal...
Background: The analysis of a renal biopsy is made complex by multifactorial etiologies involving different compartments. Recent proteomic data, pattern-based classification, and better understanding various glomerular diseases have underscored the importance immunohistology as an integral part diagnostic evaluation biopsies. These include immunofluorescence on formalin-fixed paraffin-embedded tissue (IF-P), IgG subclass staining, typing amyloid other organized deposits, classification...
Plasma cell neoplasms represent autonomous proliferations of plasma cells and can manifest as diffuse myeloma with systemic involvement (plasma or multiple myeloma), monoclonal gammopathy undetermined significance (MGUS), variants such indolent myeloma, smoldering osteosclerotic leukaemia non-secretory myeloma. Localized neoplastic proliferation presents solitary plasmacytoma bone extramedullary plasmacytoma. Involvement orbit occur a plasmacytoma, part in the clinical outcome being...
Desmoplastic infantile gangliogliomas (DIGs) are rare intracranial, cystic tumors, usually detected within the first 2 years of life. Histologically, these tumors characterized by intense desmoplasia and a divergent astrocytic neuronal differentiation. Less than 60 well‐documented cases this extremely tumor reported in literature. We present case 10‐month‐old male child presenting with large, cystic, intracranial lesion having characteristic histological features DIG. In addition, also...
Cast nephropathy is the most frequent pattern of renal involvement in multiple myeloma characterized by presence tubular casts with characteristic morphology that are composed monotypic (either kappa or lambda) light chains as seen immunofluorescence microscopy. Rarely these may show evidence amyloidogenesis and assume a unique morphology, which needs to be appreciated for arriving at accurate diagnosis. We present case an elderly male presenting features acute kidney injury detected...
Abstract Background COVID-19 infection in kidney transplant recipients often lead to allograft dysfunction. The injury has various histopathological manifestations. Our case illustrates the unusual combination of rejection, acute secondary oxalate nephropathy and SARS CoV-2 as cause irreversible failure. Case presentation A 56 year old renal recipient presented with a history fever diarrhoea for preceding 4 weeks, tested positive Sars-CoV2 on nasal swab was found have severe dysfunction,...
Multicentric Gliomas, both supratentorial and infratentorial, with varying histopathological picture is extremely rare. We report a unique occurrence of such combination in 50-year-old man who presented features elevated intracranial pressure, ataxia vertigo. Magnetic resonance imaging showed diffuse non-enhancing lesion the temporal lobe insula another non-contigous well defined enhancing cerebellum. Both lesions had mass effect. The were decompressed; first then cerebellar lesion....
Collapsing glomerulopathy (CG) is a pathological entity characterized by collapse and wrinkling of glomerular tuft, podocyte dedifferentiation hyperplasia. CG may be idiopathic or secondary to other diseases. has been described with IgA nephropathy, membranous glomerulopathy, diabetic lupus nephritis. However, till date there no report in association the anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV). Here, we present case that developed during follow-up AAV biopsy...
Sharma, Alok MS, MCh; Pandey, Ajay Diyora, Batuk MS; Shah, Sanjay DNB; Sayal, Parag MBBS; Dwivedi, Nishant MBBS Author Information
Monoclonal secretion of light chains can affect the kidney with varied morphologic manifestations. Myeloma cast nephropathy, proximal tubulopathies, monoclonal immunoglobulin deposition disease, amyloidosis, and tubulointerstitial nephritis are often noted in renal biopsy these patients. Most histopathological manifestations only one compartment nephron (tubules, capillaries, glomerulus). Case reports a combination nephropathy chain disease also reported literature. Here we report an unusual...
Giant axonal neuropathy is a rare disorder of autosomal recessive inheritance, morphologically characterized by accumulation neurofilaments in enlargements preterminal regions central and peripheral axons. We present 7-year-old girl with thick tightly curled lackluster hair suffering from giant neuropathy. The diagnosis was confirmed on the brain MRI which showed white matter abnormalities anterior posterior periventricular as well cerebellar matter. In view same, patient given intrathecal...
Mucosal-derived galactose-deficient IgA is central to the pathogenesis of primary nephropathy (IgAN). Recent reports suggest similar in Henoch-Schonlein purpura (HSP) and secondary IgAN. Its role other IgA-containing glomerular diseases still under investigation. It can be detected glomeruli with recently described antibody KM55. We aimed evaluate KM55 by immunostaining a wide spectrum diseases.After standardization colocalization case IgAN, 60 cases including HSP, chronic liver disease...
Dear Editor, A variety of kidney leasions are seen in patients with rheumatois arthritis (mesangial glomerulonephritis, IgA nephropathy, membranous etc.), tubulointerstitium (interstitial nephritis), and the vessels (rheumatoid vasculitis).[1] Amyloidosis is also long-standing RA often AA type as described literature.[2] We report a case lady multiple joint deformities who presented to us proteinuria backache. Her investigations revealed anemia (hemoglobin 10.5 g/dl), normal renal functions...