A5091525679- Radiation Therapy and Dosimetry
- Advanced Radiotherapy Techniques
- Radiation Detection and Scintillator Technologies
- Radiation Dose and Imaging
- Nuclear Physics and Applications
- Medical Imaging Techniques and Applications
- Hepatocellular Carcinoma Treatment and Prognosis
- Advanced X-ray and CT Imaging
- Radiation Effects in Electronics
- Radiation Shielding Materials Analysis
- Nuclear reactor physics and engineering
- Graphite, nuclear technology, radiation studies
- Renal cell carcinoma treatment
- Liver Disease Diagnosis and Treatment
- Prostate Cancer Diagnosis and Treatment
- Cerebrospinal fluid and hydrocephalus
- Digital Radiography and Breast Imaging
- Advances in Oncology and Radiotherapy
- Ocular and Laser Science Research
- Brain Metastases and Treatment
- Hepatitis B Virus Studies
- Neutrino Physics Research
- Cancer, Hypoxia, and Metabolism
- Cancer Genomics and Diagnostics
- Glioma Diagnosis and Treatment
Samsung Medical Center
2015-2025
Sungkyunkwan University
2015-2023
Seoul National University Bundang Hospital
2022
Weatherford College
2022
National Cancer Center
2011-2013
Hanyang University
2008-2011
The purpose of this report is to describe the proton therapy system at Samsung Medical Center (SMC-PTS) including beam generator, irradiation system, patient positioning position verification respiratory gating and operating safety control review current status SMC-PTS.The SMC-PTS has a cyclotron (230 MeV) two treatment rooms: one room equipped with multi-purpose nozzle other dedicated pencil scanning nozzle. generator energy selection can lower protons down 70 MeV from maximum 230 MeV.The...
Patient's respiratory motion can significantly affect the treatment accuracy and efficiency of radiotherapy, making effective control essential. One option is gating therapy, which allows only during specific phases cycle but typically increases time. Therefore, optimizing beam-on-time (BoT) in therapy needed. This study examines BoT proton line-scanning for liver cancer patients, with aim minimizing We calculated beams 101 by using a simulated signal. was defined as ratio to total time, sum...
This study was conducted to compare clinical outcomes and treatment-related toxicities after stereotactic body radiation therapy (SBRT) with two different dose regimens for small hepatocellular carcinomas (HCC) ≤3 cm in size. Materials and.We retrospectively reviewed 44 patients liver-confined HCC treated between 2009 2014 SBRT. Total doses of 45 Gy (n = 10) or 60 34) 3 fractions were prescribed the 95% isodose line covering planning target volume. Rates local control (LC), intrahepatic...
In particle radiotherapy, range uncertainty is an important issue that needs to be overcome. Because high-dose conformality can achieved using a beam, small affect tumor control or cause normal-tissue complications. From this perspective, the treatment planning system (TPS) must accurate. However, there well-known inaccuracy regarding dose computation in heterogeneous media. This means verifying level one of prerequisites for TPS commissioning. We evaluated accuracy algorithm implemented...
Purpose This study aimed to evaluate the initial outcomes of proton beam therapy (PBT) for hepatocellular carcinoma (HCC) in terms tumor response and safety. Materials Methods HCC patients who were not indicated standard curative local modalities treated with PBT at Samsung Medical Center from January 2016 February 2017 enrolled. Toxicity was scored using Common Terminology Criteria Adverse Events (CTCAE) version 4.0. Tumor evaluated modified Response Evaluation Solid Tumors (mRECIST)....
Proton therapy is a rapidly progressing field for cancer treatment. Globally, many proton facilities are being commissioned or under construction. Secondary neutrons an important issue during the commissioning process of facility. The purpose this study to model and validate scanning nozzles at Samsung Medical Center (SMC) by Monte Carlo simulation beam commissioning. After commissioning, secondary neutron ambient dose from nozzle (Gantry 1) was simulated measured. This performed evaluate...
In theory, the sharp dose falloff at distal end of a proton beam allows for high conformal to target. However, conformity has not been fully achieved in practice, primarily due range uncertainty, which is approximately 4% and varies slightly across institutions. To address this issue, we developed new verification system prototype: multi-slit prompt-gamma camera (MSPGC). This features detection sensitivity, an advanced estimation algorithm, precise positioning system. We evaluated...
This study aimed to compare the early hematological dynamics and acute toxicities between proton beam craniospinal irradiation (PrCSI) photon (PhCSI) for pediatric brain tumors.We retrospectively reviewed patients with tumors who received (CSI). The average change in hemoglobin levels (ΔHbavg), absolute lymphocyte counts (ΔALCavg), platelet (ΔPLTavg) from baseline values was evaluated compared PrCSI PhCSI groups at 1 2 weeks after initiation of CSI, week before end radiotherapy, 3-4...
The risk of secondary cancers after radiation therapy has become an important issue, mainly because advanced treatment techniques such as 3-D conformal (CRT) and intensity-modulated (IMRT) tend to increase the dose out-of-field organs.Moreover, cancer patients' average survival period, following those advances in techniques, also increased, effectively raising risks for same levels exposure.In present study, organs were determined some representative cases CRT by measuring organ doses with...
The primary objective of this study was to measure secondary neutron dose during proton therapy using a detector that covers the entire energy range produced in therapy. We analyzed and compared treatment with passive scattering line scanning. ambient equivalents were measured 190 MeV wobbling line-scanning beam. center plastic water phantom (30 × 30 60 cm3) placed at isocenter. A Wide-Energy Neutron Detection Instrument (WENDI-2) located 1m from isocenter four different angles (0°, 45°, 90°...
The two-dosimeter method, which employs one dosimeter on the chest and other back, determines effective dose with sufficient accuracy for complex or unknown irradiation geometries. a suitable algorithm, neither significantly overestimates (in most cases) nor seriously underestimates dose, not even extreme exposure Recently, however, definition of itself was changed in ICRP Publication 103; that is, organ tissue configuration employed calculations along related weighting factors, modified. In...
Purpose The purpose of this study was to investigate the feasibility two‐dimensional (2D) dose distribution deconvolution using convolutional neural networks (CNNs) instead an analytical approach for in‐house scintillation detector that has a detector‐interface artifact in penumbra region. Methods Datasets 2D distributions were acquired from medical linear accelerator Novalis Tx. datasets comprise two different sizes square radiation fields and 13 clinical intensity‐modulated treatment...
Purpose: A new automatic quality assurance (AutoRCQA) system using a three‐dimensional scanner (3DS) with automation was developed to improve the accuracy and efficiency of (QA) procedure for proton range compensators (RCs). The performance evaluated clinical implementation. Methods: AutoRCQA consists measurement (3DMS) based on 3DS in‐house verification software (3DVS). To verify geometrical accuracy, planned RC data (PRC), calculated treatment planning (TPS), were reconstructed...
For accurate respiration gated radiation therapy, compensation for the beam latency of control system is necessary. Therefore, we evaluate deep learning models predicting patient signals and investigate their clinical feasibility. Herein, long short-term memory (LSTM), bidirectional LSTM (Bi-LSTM), Transformer are evaluated. Among 540 signals, 60 used as test data. Each remaining 480 was spilt into training validation data in a 7:3 ratio. A total 1000 ms signal sequence (T s ) entered to...
AbstractIn this study, a high-quality voxel model of Korean adult male was constructed using the Visible Human (VKH) project's serially sectioned anatomical images. The VKH images are transverse color photographs obtained from serial sectioning an cadaver (164 cm, 55 kg) at 0.2 mm intervals. A total 28 organs and tissues were segmented with photographic height weight model, VKH-Man, is 164 cm 59.6 kg, respectively. resolution 1.875 × 2 mm. developed implemented into Monte Carlo particle...
The aim of this work was to study the feasibility proton radiography (pRad) as a patient-specific range compensator (RC) quality assurance (QA) tool and validate its clinical utility by performing QA on RCs having three kinds possible defects. In order achieve pRad for single EBT film, beam currents were modulated with new weighting factors, maximizing linearity optical-density-to-thickness ratio. Two RCs, examined be accurately manufactured planned, selected estimate our pRad. optical...