A5036234656- Obesity, Physical Activity, Diet
- Nutritional Studies and Diet
- Diet and metabolism studies
- Eating Disorders and Behaviors
- Diet, Metabolism, and Disease
- Fatty Acid Research and Health
- Birth, Development, and Health
- Consumer Attitudes and Food Labeling
- Nutrition, Genetics, and Disease
- Genetic Associations and Epidemiology
- Vitamin D Research Studies
- Breastfeeding Practices and Influences
- Regulation of Appetite and Obesity
- Stress Responses and Cortisol
- Child Nutrition and Feeding Issues
- Infant Nutrition and Health
- Liver Disease Diagnosis and Treatment
- School Health and Nursing Education
- Renal function and acid-base balance
- Maternal Mental Health During Pregnancy and Postpartum
- Health and Lifestyle Studies
- Gastroesophageal reflux and treatments
- Circadian rhythm and melatonin
- Biochemical Analysis and Sensing Techniques
- Adrenal Hormones and Disorders
Paderborn University
2021-2023
Evangelisches Krankenhaus Düsseldorf
2022-2023
University of Duisburg-Essen
2016-2022
Essen University Hospital
2019-2021
Marien Hospital Wesel
2016-2020
University of Bonn
2008-2016
TU Dortmund University
2016
Forschungsinstitut für Kinderernährung
2007-2015
University of Cologne
2008
OBJECTIVE. The study tested whether a combined environmental and educational intervention solely promoting water consumption was effective in preventing overweight among children elementary school. METHODS. participants this randomized, controlled cluster trial were second- third-graders from 32 schools socially deprived areas of 2 German cities. Water fountains installed teachers presented 4 prepared classroom lessons the group (N = 17) to promote consumption. Control 15) did not receive...
To examine the hypothesis that normalization of low circulating leptin levels in patients with anorexia nervosa ameliorates hyperactivity, three seriously ill females hyperactivity were treated off-label metreleptin (recombinant human leptin) for up to 14 days. Drive activity, repetitive thoughts food, inner restlessness, and weight phobia decreased two patients. Surprisingly, depression improved rapidly all No serious adverse events occurred. Due obvious limitations uncontrolled case...
In the present study relationship between consumption of different beverage groups and body-weight status in 5 years participation German adolescents was investigated. We used anthropometric dietary data from 3 d weighed records 244 subjects 9 18 age participating Dortmund Nutritional Anthropometric Longitudinally Designed (DONALD) study. Only with at least four out six possible were considered. A repeated-measures regression model (PROC MIXED) to analyse effect on status. BMI standard...
Abstract Objective Highly processed foods such as convenience usually have a high salt content and therefore might indirectly act adipogenic due to an increasing consumption of sugar-containing beverages (SCB). We examined the association between dietary body weight status. Design used data on urinary Na excretion indicator BMI standard deviation score (BMI-SDS) percentage fat (%BF) children adolescents participating in DONALD (Dortmund Nutritional Anthropometric Longitudinally Designed)...
While observational studies show an association between 25(OH)vitamin D concentrations and depressive symptoms, intervention studies, which examine the preventive effects of vitamin supplementation on development depression, are lacking. To estimate role lowered in etiology disorders, we conducted a two-sample Mendelian randomization (MR) study i.e., "depressive symptoms" (DS,
With this case report we support our medical hypothesis that metreleptin treatment ameliorates starvation related emotional, cognitive and behavioral symptomatology of anorexia nervosa (AN) show for the first time strong effects in a male patient with AN. A 15.9 year old adolescent severe AN eight-month duration was treated off-label metreleptin. Hyperactivity assessed accelerometry. Visual analogue scales (VAS), validated self- clinician rating lab results tracked changes from baseline to...
The authors prospectively examined whether change in dietary glycemic index (GI), load (GL), fiber intake, or whole-grain intake during puberty is associated with concurrent percentage of body fat (%BF) mass (BMI; weight (kg)/height)(2). Linear mixed-effects regression analyses were performed 215 participants from the Dortmund Nutritional and Anthropometric Longitudinally Designed (DONALD) Study (Dortmund, Germany) who possessed weighed 3-day records anthropometric data at onset (defined by...
Dietary fatty acids (FA) play a role in several (patho)physiological processes at any age, and different FA have effects on lipid status health outcome. The present study aims to describe the intake its main food sources population of healthy European adolescents assess variation as function non-dietary factors. was assessed with 24 h recall interviews 1804 aged 12·5–17·5 years. Usual intakes were calculated using multiple source method. Multilevel analyses, adjusting for centre, used...
In the present study relationship of sugar-sweetened beverage (SSB) consumption with intake single nutrients and total diet quality in German children adolescents was evaluated using a repeated-measures regression analysis model. We used dietary data from 7145 three-day weighed records 1069 subjects aged 2–19 years participating Dortmund Nutritional Anthropometric Longitudinally Designed (DONALD) Study. Intake macronutrients as percentage energy (%En), micronutrients reference values (intake...
Blood immunoreactive biomarkers, such as C-reactive protein (CRP), and metabolic abnormalities have been associated with schizophrenia. Studies comprehensively bidirectionally probing possible causal links between blood constituents liability to schizophrenia are lacking.To disentangle putative CRP levels in both directions, we conducted multiple univariable Mendelian-randomization (MR) analyses, ranging from fixed-effect inverse variance-weighted (IVW), weighted-median, MR Egger generalized...
Abstract Purpose While observational studies revealed inverse associations between serum vitamin D levels [25(OH)D] and depression, randomized controlled trials (RCT) in children adolescents are lacking. This RCT examined the effect of an untreated deficiency compared to immediate 3 supplementation on depression scores during standard day in-patient psychiatric treatment. Methods Patients with [25(OH)D ≤ 30 nmol/l] at least mild [Beck Depression Inventory II (BDI-II) > 13] ( n = 113) were...
Objective: The study analyzed the effect of a combined environmental and educational intervention solely promoting water consumption on incidence overweight among school children. Methods: 2,950 second third graders 32 elementary schools in socially deprived neighborhoods two German cities participated randomized controlled trial (August 2006–June 2007). In (N = 17), fountains were installed, each child received bottle, teachers performed classroom lessons to promote consumption. Control 15)...
Abstract An intervention study showed that promoting water consumption in schoolchildren prevented overweight, but a mechanism linking to overweight was not substantiated. We investigated whether increased replaced sugar-containing beverages and changes or influenced body weight outcomes. In secondary analysis of the Germany, we analysed combined longitudinal data from control groups. Body height were measured beverage self-reported by 24-h recall questionnaire at beginning end school year...
The COVID-19 pandemic and public measures have a direct impact on the nutrition situation; studies show changes in food consumption, eating behavior or body weight but complex pattern analyses of rarely exist.During first German lockdown, web-based survey was conducted among adults. It included 33 questions about intake, habits physical activity, as well anthropometrics sociodemographic factors. Patterns change were calculated based intake using two-step cluster analysis. To identify...