A5077377042- Oral microbiology and periodontitis research
- Oral and gingival health research
- HIV/AIDS oral health manifestations
- Streptococcal Infections and Treatments
- Enzyme Production and Characterization
- Plant Pathogenic Bacteria Studies
- Glycosylation and Glycoproteins Research
Malmö University
2023-2024
Genovis (Sweden)
2023-2024
Lund University
2016
Aim: The aim of this study was to identify and characterize EndoS-like enzymes in Streptococcus dysgalactiae subspecies (SDSD). Materials & methods: PCR, DNA sequencing, recombinant protein expression, lectin blot, ultra high performance liquid chromatography analysis a chitinase assay were used ndoS-like genes EndoSd. Results: EndoSd found four SDSD strains. hydrolyzes the chitobiose core glycan on IgG. amino acid sequence is 70% identical EndoS S. pyogenes, but it has unique C-terminal...
MUC5B is the predominant glycoprotein in saliva and instrumental establishment maintenance of multi-species eubiotic biofilms oral cavity. Investigations aciduric Lactobacillaceae family, its role emphasizes diversity across different genera proteolytic systems involved nutritional utilization mucins. We have characterized a protease from Limosilactobacillus fermentum, MdpL (Mucin degrading Limosilactobacillus) with high protein backbone similarity commensals that exploit mucins for...
Oral biofilms, comprising hundreds of bacteria and other microorganisms on oral mucosal dental surfaces, play a central role in health disease dynamics. Streptococcus oralis , key constituent these contributes significantly to the formation which, serving as an early colonizer microcolony scaffold. The interaction between S. orally predominant mucin, MUC5B, is pivotal biofilm development, yet mechanism underlying MUC5B degradation remains poorly understood. This study introduces MdpS (Mucin...