A5086210858- Autism Spectrum Disorder Research
- Family and Disability Support Research
- Child Development and Digital Technology
- Child Nutrition and Feeding Issues
- Attention Deficit Hyperactivity Disorder
- Behavioral and Psychological Studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Culinary Culture and Tourism
- Perfectionism, Procrastination, Anxiety Studies
- Neural and Behavioral Psychology Studies
- Music History and Culture
- Impact of Technology on Adolescents
- Language Development and Disorders
- Bipolar Disorder and Treatment
- Virology and Viral Diseases
King's College London
2018-2024
University of Oxford
2019
Autistic children can have difficulty generalising treatment effects beyond the immediate context. Paediatric Autism Communication Therapy (PACT) has been successful when delivered in clinic. Here we tested Therapy-Generalised (PACT-G) intervention combined between home and education settings for its overall effect mechanistic transmission of across contexts.In this parallel, single-blind, randomised, controlled trial, recruited autistic aged 2-11 years urban or semi-urban areas Manchester,...
Background There are very few mechanistic studies of the long‐term impact psychosocial interventions in childhood. The parent‐mediated Paediatric Autism Communication Therapy (PACT) RCT showed sustained effects on autistic child outcomes from pre‐school to mid‐childhood. We investigated mechanism by which PACT intervention achieved these effects. Methods Of 152 children randomised receive or treatment as usual between 2 and 5 years age, 121 (79.6%) were followed 5–6 after endpoint at a mean...
Despite increasing use of social media and the potential benefits for people with anxiety (SA) disorder, little is known about online experience SA. Our study aimed to investigate occurrence cognitive behavioral processes during a series off-line Facebook (FB)-based tasks among individuals high low levels Sixty-one undergraduates or SA were asked FB in laboratory setting, make an post, imagine three ambiguous scenarios. Participants reported higher throughout interaction effect, indicating...
Measuring outcomes for autistic children following social communication interventions is an ongoing challenge given the heterogeneous changes, which can be subtle. We tested and compared overall item-level intervention effects of Brief Observation Social Communication Change (BOSCC), Autism Diagnostic Schedule (ADOS-2) algorithm, ADOS-2 Calibrated Severity Scores (CSS) with aged 2-5 years from Preschool Trial (PACT). The BOSCC was applied to Module 1 ADOS assessments (ADOS-BOSCC). Among 117...
Anxiety is a prevalent and impairing co-morbidity among individuals with autism spectrum disorder (ASD), yet assessment measures, including screening tools, are seldom validated samples. We explored the psychometric properties of child parent reports Spence Children's Scale (SCAS) Screen for Related Disorder-71 (SCARED-71) 49 males ASD (10-16 years, 63% co-occurring anxiety). Both measures had excellent internal consistency fair-good parent-child agreement. The SCAS has higher proportion...
One core component of the Paediatric Autism Communication Therapy–Generalised involves supporting parents to change their interaction and communication style with child. This behaviour has been found affect child outcomes. Implementation science methodologies offer a range opportunities investigate how interventions are delivered in practice; however, few autism intervention studies have used such designs explore parents. We interviewed 27 explored use strategies after trial. employed...
Abstract We investigated autistic children’s generalisation of social communication over time across three settings during a play-based assessment with different adults and explore the potential moderating effects on age, nonverbal IQ level restricted repetitive behaviours. The abilities 248 children (2–11 years, 21% female, 22% single parent, 60% white) from UK sites were assessed 1984 video interactions in contexts interaction partners (parent/home, teaching assistant/school,...
Background Prior evidence suggests that behaviours closely related to the intervention delivered for autism are amenable change, but it becomes more difficult when generalising treatment effects beyond immediate context. Objectives The objectives were (1) test an early social communication designed promote child change in naturalistic contexts of both home and education, with additive effect on overall symptom outcomes, (2) conduct a mechanistic study investigating transmission within across...
A wealth of parent-report research shows adaptive functioning difficulties in autistic children, with influenced by a number child factors. Adaptive children is known to vary across settings; however, no has yet explored factors influencing education professional-report. This study investigated the rate and profile impairment, professional-reported skills 248 children. Twelve were < 3 years (min age for available normative data on function measure), so removed from analyses. Results...
Adults with attention-deficit/hyperactivity disorder (ADHD) or bipolar (BD) may display similar cognitive impairments and clinical symptoms, which might reflect shared mechanisms. Initial evidence indicates disorder-specific overlapping neurophysiological alterations using event-related potentials (ERPs) in individuals BD ADHD during attentional tasks, but it is unknown whether generalize across other processes tasks. We conduct the first comparison between women (n = 20), 20) control on...