- Cancer-related molecular mechanisms research
- Calpain Protease Function and Regulation
- Angiogenesis and VEGF in Cancer
- Pain Mechanisms and Treatments
- Spaceflight effects on biology
- Traumatic Brain Injury and Neurovascular Disturbances
- Trace Elements in Health
- Retinoids in leukemia and cellular processes
- Iron Metabolism and Disorders
- Genetic and phenotypic traits in livestock
- Mitochondrial Function and Pathology
- Epigenetics and DNA Methylation
- Herpesvirus Infections and Treatments
- Zoonotic diseases and public health
- Bioinformatics and Genomic Networks
- Ion-surface interactions and analysis
- Lymphatic System and Diseases
- Mass Spectrometry Techniques and Applications
- Aluminum toxicity and tolerance in plants and animals
- Photosynthetic Processes and Mechanisms
- Esophageal Cancer Research and Treatment
- Cardiac Arrest and Resuscitation
- Heme Oxygenase-1 and Carbon Monoxide
- Cell death mechanisms and regulation
- Folate and B Vitamins Research
Tianjin Medical University
2017-2023
Shaanxi University of Science and Technology
2022
Second Affiliated Hospital of Zhengzhou University
2019
BGI Group (China)
2019
Chiba Cancer Center
1995
Chloride channels (CLCs) play critical roles in anion transport, stress adaptation, and ion homeostasis plants. Whereas their genomic wide indentification functional divergence tomato (Solanum lycopersicum) remain largely unexplored. In this study, we identified nine CLC genes the genome, classifying them into two evolutionarily distinct clades (Group I II) based on phylogenetic analysis. Structural dissection revealed conserved transmembrane domains (9-12 TMDs) motif patterns (e.g., motifs...
Previous studies have suggested a possible association among dietary zinc and vitamin B6 intake CVD mortality all-cause mortality. However, evidence on the of their interactions with remains unclear. This prospective study utilized data from US National Health Nutrition Examination Survey (NHANES) 1999 to 2016. After median follow-up 10.4 years, 4757 deaths were recorded 36,081 participants. Higher levels (≥9.87 mg/day) associated lower (hazard ratio (HR) = 0.85, 95% confidence interval...
Abstract Degradation of cyclin B was effectively suppressed when cells were treated with ALLN ( N ‐acetylleucylleucylnorleucinal) which inhibits proteasome, calpain and cysteine proteinase cathepsins. In order to examine protease degrades B, the effect a cathepsin inhibitor, cystatin α, investigated. The α gene inserted into an inducible expression vector, pMSG, transfected NIH3T3 mouse fibroblasts. induced in after treatment dexamethasone. Overexpression resulted increase amount suggesting...
Abstract Background Identification of molecular alterations damaged tissue in patients with neurological disorders can provide novel insight and potential therapeutic target for treatment the diseases. It has been suggested by animal studies that connexins (CXs), a family gap junction proteins, could contribute to neuronal cell death associate deficits during trauma‐induced damage. Nevertheless, whether specific CXs are involved traumatic brain injury ( TBI ) remained unexplored human...
Abstract Background Sheep milk is an attractive nutritional and functional food source. Some Dishevelled, Egl-10 pleckstrin (DEP) domain-containing proteins can regulate lactation performance in mammals. However, systematic study of the role sheep DEP family members regulating currently lacking. This aimed to reveal roles by exploring their genetic characteristics features at whole genome-wide level. Results Twenty were identified genome, they be divided into four major groups. Ka/Ks...
Molluscum contagiosum is a common, self-limiting infectious disease of the skin caused by molluscum virus (MCV).The primarily affects children, sexually active adults, and immunocompromised individuals.Transmission occurs direct contact.Therefore, usually detected in genitals patients.However, diagnosis intracranial infection difficult if skin/mucosa lessons are atypical or absent, presence cerebrospinal fluid has not been reported.We report very rare case virus.A 25-year-old girl was...
Objective To screen the differentially expressed lncRNA in peripheral blood mononuclear cells (PBMC) of patients with chronic heart failure(CHF). Methods PBMC were separated from CHF and healthy controls, 3 each group. Total RNA was extracted PBMC. Human microarray v4 chips (CapitalBio Co.) used to detect lncRNA. Fluorescence quantitative PCR (qPCR) for identification interesting lncRNA. Results 359 up-regulated 369 down-regulated found after analyzing data microarray. HELT-3...