- Methane Hydrates and Related Phenomena
- Earthquake Detection and Analysis
- Nuclear Materials and Properties
- Radical Photochemical Reactions
- Genomics and Phylogenetic Studies
- Enzyme Production and Characterization
- Advanced biosensing and bioanalysis techniques
- Catalytic C–H Functionalization Methods
- Microbial Community Ecology and Physiology
- Fusion materials and technologies
- Advanced Nanomaterials in Catalysis
- Cardiac Ischemia and Reperfusion
- Nanoplatforms for cancer theranostics
- Sulfur-Based Synthesis Techniques
- High-Temperature Coating Behaviors
- Cardiac Valve Diseases and Treatments
- Geophysics and Gravity Measurements
- Lipid metabolism and biosynthesis
- Redox biology and oxidative stress
- Metabolomics and Mass Spectrometry Studies
- Antioxidant Activity and Oxidative Stress
- Microbial Metabolism and Applications
- Enzyme Structure and Function
- Analytical chemistry methods development
- Molecular Sensors and Ion Detection
Shandong Academy of Sciences
2017-2024
Qilu University of Technology
2016-2024
China General Nuclear Power Corporation (China)
2024
Chongqing Jiaotong University
2023
University of Leicester
2023
Beijing Anzhen Hospital
2008-2022
Capital Medical University
2008-2022
Chengdu University of Traditional Chinese Medicine
2020
California University of Pennsylvania
2020
Shanghai Jiao Tong University
2019
Abstract Herein, an environmentally friendly electrochemical approach is reported that takes advantage of the captodative effect and delocalization to generate nitrogen‐centered radicals (NCRs). By changing reaction parameters electrode material feedstock solubility, dearomatization enabled a selective dehydrogenative C−N versus N−N bond formation reaction. Hence, pyrido[1,2‐ ]benzimidazole tetraarylhydrazine frameworks were prepared through sustainable transition‐metal‐ exogenous...
Molecular electrophotocatalysis has emerged as a powerful strategy for the development of sustainable synthetic protocols. With proof-of-concept, we exploited versatile electrophotocatalytic deaminative alkylation approach. Mechanistic investigation indicated that in situ recycling alkyl radicals was key point. Notably, ligand modification and late-stage functionalization pharmaceuticals were also established, highlighting its feasibility practical utilization.
Cooperation between organelles is essential to maintain the normal functions of cells. Lipid droplets (LDs) and nucleoli, as important organelles, play an role in activities However, due lack appropriate tools, situ observation interaction them has been rarely reported. In this work, taking into full consideration pH charge differences LDs a pH-triggered reversible fluorescent probe (LD-Nu) was constructed based on cyclization-ring-opening mechanism. The vitro titration experiment 1H NMR...
A kind of biomaterial with antibacterial and mechanical properties was prepared using gelatin (GE) as a raw material. GE modified by epoxy quaternary ammonium salt (QAS) then cross-linked tannic acid (TA). Analysis the Fourier transform infrared spectroscopy (FTIR) results showed that cationic group grafted onto reaction amino QAS, cross-linking occurred between active groups TA under alkaline conditions. The degree determined fluorescence method via derivative fluorescamin. influence on...
Synthetic photoelectrochemistry shows significant advantages in handling of reactive intermediates via a sustainable way and has developed to be the frontier single electron transfer chemistry. The exploration new photoelectrocatalysts, especially uncommon metal-based ones, will contribute exploitation synthetic strategies. Benefiting from reversible redox ability photoactivity, cerium salt is expected become photo-electro-response medium generate active species. In this work, with green...
Protease-producing bacteria are widespread in ocean sediments and play important roles degrading sedimentary nitrogenous organic materials. However the diversity of proteases involved such processes remain largely unknown especially for communities enclosed sea bays. Here, we investigated extracellular protease-producing their protease types Laizhou Bay. A total 121 bacterial isolates were obtained from sediment samples 7 sites characterized. The abundance cultivable was about 104 CFU g-1...
Caffeic acid has been indicated to benefit cholesterol balance, but the effect of pure caffeic on atherosclerosis in vivo not tested. Given that and Alzheimer's disease share common features including distracted lipid balance chronic inflammation, concurrent effects atherosclerotic lesions cognitive decline were explored here by using ApoE-/- mice model. A two months' administration 20 mg/kg or saline was given once days intraperitoneally 5-month-old female mice. We found treatment reduced...
The current small-scale synthesis and relatively large size of Cu2O have limited its practical applications. Herein, we developed a hydrolysis strategy to prepare phase-pure networks composed small granules (ca. 25 nm) on gram scale. preparation involves in situ hydrolyzing the Hx[CuxCl2x] complexes prereduced N,N′-dimethylformamide (DMF). DMF-soluble are critical for homogeneous nucleation CuCl seeds subsequent hydrolysis, allowing separate control over growth stages regulate formation...
Abstract Social media platforms, as complex socio-technical ecosystems, have reshaped the way individuals access, share, and interpret information. The interplay of diverse users, rapid content flow, intricate network structures exemplifies complexity science domain, where dynamic interactions give rise to emergent patterns influence opinion formation. In this perspective, we review three key areas intelligent information dissemination on social media: (1) rumor fake news detection, (2)...
Our goal was to establish two new predictive models of prostate cancer determine whether require a biopsy when the prostate-specific antigen level is in diagnostic gray zone. A retrospective analysis 197 patients undergoing with antigens between 4 and 10 ng ml−1 conducted. Of these, 47 were confirmed have cancer, while remaining 150 diagnosed benign disease after examining pathology. Two multivariate logistic regression established including age, volumes, free/total ratio, density using SPSS...
Esterases represent an important class of enzymes with a wide variety industrial applications. A novel hormone-sensitive lipase (HSL) family esterase, Est19, from the Antarctic bacterium Pseudomonas sp. E2-15 is identified, cloned, and expressed. The enzyme possesses GESAG motif containing active serine (S) located within highly conserved catalytic triad Ser155, Asp253, His282 residues. efficiency (kcat/Km) Est19 for pNPC6 substrate 148.68 s−1mM−1 at 40 °C. Replacing Glu154 juxtaposed to...
The effect of FeCrAl sublayer composition on the microstructure and lead-bismuth eutectic corrosion behavior FeCrAl/YSZ (Yttria-stabilized zirconia) composite coatings was systematically investigated by SEM XRD. results show that as a diffusion barrier bonding layer is beneficial to improve resistance coatings. After corrosion, slow-growing, continuous, protective Al-rich oxide formed at interface between YSZ sublayer, which effectively hinders inward oxygen atoms outward iron atoms....