Luis O. Leal

ORCID: 0000-0003-1630-3447
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About
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Research Areas
  • Respiratory Support and Mechanisms
  • Fungal Infections and Studies
  • Antifungal resistance and susceptibility
  • Neutropenia and Cancer Infections
  • Immunodeficiency and Autoimmune Disorders
  • Bone and Joint Diseases
  • Research on Leishmaniasis Studies
  • Long-Term Effects of COVID-19
  • Immune responses and vaccinations
  • Foot and Ankle Surgery
  • Immunotherapy and Immune Responses
  • COVID-19 Clinical Research Studies
  • Neonatal Respiratory Health Research
  • Shoulder and Clavicle Injuries
  • Lower Extremity Biomechanics and Pathologies
  • Inhalation and Respiratory Drug Delivery
  • Hip disorders and treatments

American Podiatric Medical Association
1991

We are learning that the host response to severe acute respiratory syndrome coronavirus 2 ( SARS-CoV-2) infection is complex and highly dynamic. Effective initial defense in lung associated with mild symptoms disease resolution. Viral evasion of immune can lead refractory alveolar damage, ineffective repair mechanisms, systemic inflammation organ dysfunction. The these patients variable include moderate and/or marked suppression. There unlikely be a "one size fits all" approach...

10.1093/cid/ciaa904 article EN cc-by-nc-nd Clinical Infectious Diseases 2020-06-29

Abstract Background Sargramostim (yeast-derived, glycosylated recombinant human granulocyte-macrophage colony-stimulating factor [rhu GM-CSF]) augments innate and adaptive immune responses accelerates hematopoietic recovery of chemotherapy-induced neutropenia. However, considerably less is known about its efficacy as adjunctive immunotherapy against invasive fungal diseases (IFDs). Methods The clinical courses 15 patients with pediatric malignancies IFDs treated adjunctively sargramostim at...

10.1093/ofid/ofac535 article EN cc-by-nc-nd Open Forum Infectious Diseases 2022-10-11

10.1016/s0891-8422(23)00471-8 article EN Clinics in Podiatric Medicine and Surgery 1991-07-01

10.1016/s0891-8422(23)00466-4 article Clinics in Podiatric Medicine and Surgery 1991-07-01
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