A5091713074- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- Cardiac, Anesthesia and Surgical Outcomes
- Infective Endocarditis Diagnosis and Management
- Cardiac tumors and thrombi
- Cardiac Imaging and Diagnostics
- Congenital Heart Disease Studies
- Intensive Care Unit Cognitive Disorders
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac and Coronary Surgery Techniques
- Anesthesia and Neurotoxicity Research
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Cardiovascular Effects of Exercise
- Coronary Interventions and Diagnostics
- Cardiac Arrest and Resuscitation
- Acute Kidney Injury Research
- Pericarditis and Cardiac Tamponade
- Hemodynamic Monitoring and Therapy
- Cardiovascular Function and Risk Factors
- Traumatic Brain Injury and Neurovascular Disturbances
- Aortic Disease and Treatment Approaches
- Aortic aneurysm repair treatments
- Cardiac electrophysiology and arrhythmias
- Tracheal and airway disorders
Rabindranath Tagore Medical College
2019-2025
Ahmedabad Civil Hospital
2013-2024
Miller Children's & Women's Hospital
2013-2023
University of California, Los Angeles
2022
University Hospital Coventry
2000-2021
University of Minnesota
2021
Valley Medical Center
2021
University of Washington
2021
University of Hawaii System
2021
Medical University of the Americas
2021
Abstract Background Atypical teratoid/rhabdoid tumor (AT/RT) of the central nervous system (CNS) is a rare embryonal neoplasm early childhood with dismal outcome and no current uniformly accepted treatment. Given its highly aggressive nature predilection for dissemination at diagnosis, intensive multimodal therapy required. Materials Methods Nineteen children newly diagnosed CNS AT/RT were treated on head start (HS) III protocol. Treatment consisted surgical resection, 5 cycles induction...
Statins play a key role in the management of atherosclerotic cardiovascular disease for both primary and secondary prevention. However, their increasing usage has correspondingly led to higher incidence adverse effects, with muscle symptoms being most common. An intriguing drug interaction exists between ticagrelor high-intensity statins, which may exacerbate effects statin-induced rhabdomyolysis, leading significant consequences. This study was conducted examine profile patients who have...
Background and Aims: The effect of vitamin C on vasopressor requirement in critically ill patients have been evaluated previously. We aimed to evaluate the C, hydrocortisone thiamine mortality post-operative adult cardiac surgical with septic shock. Methods: About 24 shock were randomised into Group 1 (receiving matching placebo per day for 4 days) 2 6 g 400 mg 200 days). Vasopressor dose over days therapy was primary endpoint, whereas in-hospital secondary endpoint. Results: APACHE IV...
Abstract Background Sargramostim (yeast-derived, glycosylated recombinant human granulocyte-macrophage colony-stimulating factor [rhu GM-CSF]) augments innate and adaptive immune responses accelerates hematopoietic recovery of chemotherapy-induced neutropenia. However, considerably less is known about its efficacy as adjunctive immunotherapy against invasive fungal diseases (IFDs). Methods The clinical courses 15 patients with pediatric malignancies IFDs treated adjunctively sargramostim at...
Journal Article Hyperperfusion and cerebral dysfunction. Effect of differing acid-base management during cardiopulmonary bypass Get access European Cardio-Thoracic Surgery, Volume 7, Issue 9, September 1993, Pages 457–463, https://doi.org/10.1016/1010-7940(93)90274-F Published: 01 1993
Myocardial fibrosis occurs in end-stage heart failure secondary to mitral regurgitation (MR), but it is not known whether this present before onset of symptoms or myocardial dysfunction. This study aimed characterise chronic severe primary MR on histology, compare tissue characterisation cardiovascular magnetic resonance (CMR) imaging, and investigate associations with symptoms, left ventricular (LV) function, exercise capacity. Patients class I IIa indications for surgery underwent CMR...
<b>Aim:</b> Long standing mitral valve disease is usually associated with severe pulmonary hypertension. Perioperative hypertension a risk factor for right ventricular (RV) failure and cause morbidity mortality in patients undergoing replacement. Phosphodiesterase 5 inhibitor-sildenafil citrate widely used to treat primary There lack of evidence effects oral sildenafil on secondary due disease. The study aims assess the effectiveness preoperative incidence RV replacement surgery.<br>...
Objective: Transposition of the great arteries is a common congenital heart disease.Arterial switch gold standard operation for this complex in presence intramural coronary artery surgically most demanding even experienced hands.We are presenting our experience with modified technique arterial operation.Methods: This prospective study involves 450 patients undergoing at institute from April 2006 to December 2013 (7.6 years).Eighteen underwent artery.The patterns and used detailed...
Reinstitution of step-up care (recidivism) following cardiac surgery may be associated with increased mortality. This has, however, not been widely reported.We, therefore, studied 8113 consecutive patients who underwent coronary artery bypass grafting (CABG), valve replacement/repair or combined valve+CABG between January 1996 and December 2003 to determine the reasons for readmission intensive unit (ICU) their outcomes in terms length stay (i) ICU (ii) hospital (iii) in-hospital mortality...
Early goal-directed therapy (EGDT) provides preset goals to be achieved by intravenous fluid and inotropic with earliest detection of change in the hemodynamic profile. Improved outcome cardiac surgery patients has been shown perioperative volume optimization, while postoperative intensive care unit (ICU) stay can decreased improving oxygen delivery. Our aim this study was EGDT undergoing elective surgery.This is a prospective single institute involving total 478 patients. Patients were...
Improving tissue oxygenation is one of most important tasks in management low cardiac output. Central venous oxygen saturation (ScvO2) and lactate are established criteria for monitoring the adequacy oxygenation. The venous-to-arterial carbon dioxide difference [P(v-a)CO2] inversely associated with output.To study use P(v-a)CO2/C(a-v)O2 ratio as a marker output during Cardiopulmonary Bypass (CPB) paediatric surgical patients.The present was prospective observational conducted over period...
The optimal management of chronic severe primary degenerative mitral regurgitation (MR) is to repair the valve but identification timing surgery remains challenging. Current guidelines suggest 'watchful waiting' until onset symptoms or left ventricular (LV) dysfunction these have been challenged as promoting 'rescue surgery'. Better predictors are required inform decision-making in relation necessity and surgery. Chronic volume overload a stimulus for adverse adaptive LV remodelling....