A5008736377- Lung Cancer Treatments and Mutations
- Lung Cancer Diagnosis and Treatment
- Lung Cancer Research Studies
- Colorectal Cancer Treatments and Studies
- Anesthesia and Pain Management
- Anesthesia and Neurotoxicity Research
- Anesthesia and Sedative Agents
- Cancer Genomics and Diagnostics
- Cancer-related molecular mechanisms research
- Ginseng Biological Effects and Applications
- Brain Metastases and Treatment
- Medical Imaging and Pathology Studies
- Pharmacological Effects of Natural Compounds
- Cancer Cells and Metastasis
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Airway Management and Intubation Techniques
- Cancer Treatment and Pharmacology
- Phytochemistry and Biological Activities
- Pain Mechanisms and Treatments
- Neuroendocrine Tumor Research Advances
- Spine and Intervertebral Disc Pathology
- Peptidase Inhibition and Analysis
- Gastric Cancer Management and Outcomes
- Nausea and vomiting management
- Cardiac Ischemia and Reperfusion
Union Hospital
2011-2024
Jilin University
2015-2024
Union Hospital
2014-2023
China Academy of Chinese Medical Sciences
2018-2023
Chongqing Academy of Chinese Materia Medica
2005-2023
Weatherford College
2023
Credo Reference (United States)
2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2010-2021
University of Benin
2021
Peking Union Medical College Hospital
2009-2018
Inadvertent intraoperative hypothermia (core temperature <36°C) is a frequently preventable complication with several adverse consequences. Our study aimed to determine the overall incidence of inadvertent and its risk factors associated clinical outcomes in this national survey China.We conducted cross-sectional 30 days postoperative follow-up from November 2014 through August 2015. A total 3132 eligible patients underwent general anesthesia were randomly selected 28 hospitals nationwide...
<b><i>Background:</i></b> Epidermal growth factor receptor (EGFR) mutations play essential roles in the treatment of non-small cell lung cancer (NSCLC) patients using EGFR tyrosine kinase inhibitors. Detection blood cell-free DNA (cfDNA) seems promising. However, mutation status plasma/serum is not always consistent with that tissues. <b><i>Objectives:</i></b> The aims this study were to compare statuses plasma those tissues and thus determine...
Abstract Background Breast cancer is one the most common cancers, making it second leading cause of cancer-related death among women. Long non-coding RNAs (lncRNAs), with tightly regulated expression patterns, also serve as tumor suppressor during tumorigenesis. The present study aimed to elucidate role LINC00968 in breast via WNT2-mediated Wnt2/β-catenin signaling pathway. Methods chip GSE26910 was utilized identify differential and WNT2. possible relationship LINC00968, transcriptional...
Objective:Evidences demonstrate that postoperative residual neuromuscular blockade (rNMB) is a primary and frequent anesthetic risk factor for complications. This study was designed to mitigate the paucity of data regarding occurrence degree rNMB in real-life setting.Methods:This prospective, multicenter, anesthetist-blind, observational enrolled 1571 Chinese adults undergoing elective open or laparoscopic abdominal surgery lasting ≤4 hours from 32 hospitals across China. The patients...
// Yu Zhang 1,* , Yan Xu Wei Zhong Jing Zhao 1 Minjiang Chen Li Longyun and Mengzhao Wang Department of Respiratory Medicine, Peking Union Medical College Hospital, College, Chinese Academy Sciences, Beijing, China * These authors have contributed equally to this study Correspondence to: Wang, email: Keywords : plasma cell-free DNA; droplet digital PCR; DNA concentration; epidermal growth factor receptor; advanced non-small cell lung cancer Received May 26, 2016 Accepted December 16,...
Objective. With the increasing incidence of diabetes mellitus (DM) combined with myocardial ischemia, how to reduce ischemia-reperfusion injury in DM patients has become a major problem faced by clinicians. We investigated therapeutic effects dexmedetomidine (DEX) on rats and its effect endoplasmic reticulum stress. Methods. SD SPF grade were randomly divided into 6 groups: non-DM sham operation group (NDM-S group), (NDM-IR (NDM-DEX group); diabetic (DM-S diabetes-reperfusion (DM-IR...
Paraneoplastic limbic encephalitis (PLE) is a rare autoimmune neurological syndrome observed in lung cancer patients. We retrospectively investigated the clinical characteristics, treatment responses, and prognoses 16 PLE patients who were subsequently diagnosed with cancer. Fifteen initially presented disturbance of consciousness, 13 disorientation, 12 seizures. Thirteen had autoantibodies, including eight gamma aminobutyric acid B receptor (GABABR) antibodies Hu antibodies. PET-CT revealed...
Neuropathic pain is an incapacitating disease that affects a large number of people worldwide, but effective therapies have not yet been established. microRNAs (miRs) are short non-coding RNAs participate in several biological processes and states, including neuropathic pain. Nevertheless, the precise role miRs regulating remains largely unknown. In present study, we investigated miR-218 using rat model chronic constriction injury (CCI). expression was induced studied spinal cord microglial...
Inadvertent intraoperative hypothermia (core temperature <36 °C) is a frequent but preventable complication of general anesthesia. Accurate risk assessment individual patients may help physicians identify at for and apply preventive approaches, which include active warming. This study aimed to develop validate risk-prediction model hypothermia. Two independent observational studies in China, the Beijing Regional Survey China National Survey, were conducted 2013 2014, respectively, determine...
Numerous reports have shown that cyclin-dependent kinase 5 (Cdk5), a proline-directed serine/threonine kinase, critically contributes to the induction and maintenance of chronic pain induced by peripheral inflammation nerve injury. Recent evidence has also suggested critical role an epigenetic mechanism in setting pain. The present study aims elucidate cyclic AMP response element-binding protein (CREB)-mediated upregulation Cdk5 its functional significance rats with neuropathic constriction...
Sophora japonica L. is widely consumed in China because of its medicinal and nutritional value. Its quality greatly affected by the accumulation metabolites, which varies with stage flower development. However, changes characteristics secondary metabolites during maturity remain unclear. Ultra-high-performance liquid chromatography coupled electrospray ionization-triple quadrupole-linear ion trap mass spectrometry (UPLC-ESI-QTRAP-MS/MS) revealed dynamic S. five flower-maturity stages. We...