A5064556719- Metal complexes synthesis and properties
- SARS-CoV-2 and COVID-19 Research
- RNA Interference and Gene Delivery
- Pickering emulsions and particle stabilization
- Antibiotic Resistance in Bacteria
- Research on Leishmaniasis Studies
- Nosocomial Infections in ICU
- Essential Oils and Antimicrobial Activity
- Advancements in Transdermal Drug Delivery
- Dermatology and Skin Diseases
- Colorectal Cancer Screening and Detection
- vaccines and immunoinformatics approaches
- Communication and COVID-19 Impact
- Gastric Cancer Management and Outcomes
- Immune Response and Inflammation
- Electrospun Nanofibers in Biomedical Applications
- Computational Drug Discovery Methods
- Immune Cell Function and Interaction
- Hepatitis B Virus Studies
- Neonatal Respiratory Health Research
- Advanced Drug Delivery Systems
- Vaccine Coverage and Hesitancy
- Antibiotic Use and Resistance
- Prostate Cancer Treatment and Research
- Parvovirus B19 Infection Studies
Azienda Ospedaliera Citta' della Salute e della Scienza di Torino
2020-2025
University of Turin
2012-2022
The infections of multidrug-resistant organisms (MDROs) associated with duodenoscopes during endoscopic retrograde cholangiopancreatography (ERCP) procedure have become a significant cause for concern, especially in fragile patients. While the clinical impacts these are well-documented, their economic implications remain underexplored. This study assesses incidence and burden post-ERCP Italy using an administrative database. We conducted retrospective observational databases from A.O.U....
Glioblastoma, the most common primary brain tumor in adults, has an inauspicious prognosis, given that overcoming blood-brain barrier is major obstacle to pharmacological treatment of tumors. As neoangiogenesis plays a key role glioblastoma growth, US Food and Drug Administration approved bevacizumab (BVZ), antivascular endothelial growth factor antibody for recurrent patients whose initial therapy failed. In this experimental work, BVZ was entrapped solid lipid nanoparticles (SLNs) prepared...
The pandemic caused by the COVID-19 virus has required major adjustments to healthcare systems, especially infection control and antimicrobial stewardship. objective of this study was describe incidence multidrug-resistant (MDR) hospital-acquired infections (HAIs) antibiotic consumption during three waves compare it period before outbreak at Molinette Hospital, located in City Health Sciences, a 1200-bed teaching hospital with surgical, medical, intensive care units. We demonstrated an...
Floxuridine is a very effective drug with high potency in the treatment of various tumors but its utility limited by low efficiency cellular uptake. In order to improve floxuridine uptake, lipophilic prodrug (3',5'-distearoyl-5-fluoro-2'-deoxyuridine) was synthetized and loaded into behenic acid nanoparticles produced fatty coacervation technique. Generally, spherical shaped SLN mean diameters below 300 nm were obtained. Distearoyl-floxuridine entrapment (from 70.8 82.8%). Vitro cytotoxicity...
FMOC-isocyclosporine A, a fluorescent labeled cyclosporine was encapsulated in solid lipid nanoparticles (SLN) prepared by the coacervation technique, and its anti-inflammatory activity evaluated. The of labelled molecule, measured as inhibition TNF-α secretion, is similar to native one. SLN were compared commercial formulations, through measurement cytokine release drug uptake rat peripheral blood mononuclear cells. Drug-loaded inhibit secretion lower extent than probably due cells, but...