Shinya Kohyama

ORCID: 0000-0003-1632-1960
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About
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Research Areas
  • Intracranial Aneurysms: Treatment and Complications
  • Cerebrovascular and Carotid Artery Diseases
  • Vascular Malformations Diagnosis and Treatment
  • Acute Ischemic Stroke Management
  • Neurosurgical Procedures and Complications
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Moyamoya disease diagnosis and treatment
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Cerebral Venous Sinus Thrombosis
  • Venous Thromboembolism Diagnosis and Management
  • Vascular Procedures and Complications
  • Meningioma and schwannoma management
  • Central Venous Catheters and Hemodialysis
  • Stroke Rehabilitation and Recovery
  • Aortic Disease and Treatment Approaches
  • Coronary Interventions and Diagnostics
  • Advanced MRI Techniques and Applications
  • Retinal Imaging and Analysis
  • Aortic aneurysm repair treatments
  • Glaucoma and retinal disorders
  • Infectious Aortic and Vascular Conditions
  • Cardiovascular and Diving-Related Complications
  • Kruppel-like factors research
  • Infective Endocarditis Diagnosis and Management
  • Infectious Diseases and Tuberculosis

Saitama Medical University
2016-2025

Saitama International Medical Center
2009-2024

Shinshu University
2024

Saitama Prefecture
2020-2024

National Sagamihara Hospital
2023

St. Jude Medical Center
2014

National Defense Medical College
2001-2007

Fukuoka University
2006

Osaka University
2004-2005

St. Luke's-Roosevelt Hospital Center
2003

BACKGROUND AND OBJECTIVES: Although carotid endarterectomy (CEA) and artery stenting (CAS) reduce the risk of stroke, their efficacy in improving decreased vision is unclear. This study aims to evaluate effects CEA CAS on ocular blood flow (OBF) visual acuity (VA) patients with stenosis, while also exploring possible relevance postoperative microembolisms recovery. METHODS: The results 78 procedures (CEA, 39; CAS, 39) performed 76 stenosis were prospectively analyzed. OBF was measured using...

10.1227/neu.0000000000003379 article EN Neurosurgery 2025-02-17

Most cases with chronic subdural hematoma (CSDH) are treated by simple irrigation and drainage, then more than eighty percent of them result in good recovery. But we sometimes encounter intractable re-collection, which is considered repeated bleeding from macrocapillary the capsule. Embolization middle meningeal artery (MMA) to be useful eliminate blood supply this structure. The authors experienced seven CSDH MMA embolization no recurrence took place all for up 15 months. Endovascular...

10.1177/15910199070130s121 article EN Interventional Neuroradiology 2007-03-01

Preoperative embolization of meningioma is commonly performed; however, there no consensus on the best embolic material to reduce intraoperative blood loss and surgery time.We retrospectively assessed safety efficacy 56 cases preoperative middle meningeal artery with N-butyl cyanoacrylate (NBCA) in 105 for meningioma. We also defined a tumor volume ratio compensate bias caused by volume, analyzed limited (the embolized group n = 52, non-embolized 21) convexity, parasagittal region, falx,...

10.1177/1591019915590537 article EN Interventional Neuroradiology 2015-06-26

Abstract Increase in intracellular Ca 2+ [Ca ]i regulates many biological functions including apoptosis, but the protein(s) linking and apoptosis are not completely understood. We have previously shown that IP3R‐deficient cells resistant to T‐cell receptor (TCR)‐induced due lack of release from endoplasmic reticulum (ER) calcineurin activation. Here we show caspase‐9 ‐3 activated after TCR stimulation, consistent with resistance these apoptosis. However, also demonstrate Bcl‐2 expression is...

10.1002/cbf.1050 article EN Cell Biochemistry and Function 2003-12-18

Aneurysmal recanalization is a problem with endovascular coiling and one of its risk factors the low volume embolization ratio (VER). The first coil VER (1st VER) believed to be critical for obtaining high VER. main objective this study was evaluate potentially useful selecting optimal 1st coiling.609 initial saccular aneurysmal treatments performed between January 2010 December 2014 at our institution were included in retrospective study. Attempted procedures, retreatment cases,...

10.1136/neurintsurg-2016-012877 article EN Journal of NeuroInterventional Surgery 2017-01-27

Intra-and extracranial artery dissections are uncommon but significant causes of ischemic stroke and subarachnoid hemorrhage (SAH). While individual well-documented, simultaneous multiple vessels leading to both hemorrhagic strokes extremely rare. A 41-year-old man presented with acute onset headache, vomiting, loss consciousness. Imaging revealed arterial involving the bilateral internal carotid arteries vertebral (VAs). The patient was diagnosed SAH caused by a ruptured fusiform aneurysm...

10.25259/sni_167_2025 article EN Surgical Neurology International 2025-04-25

Advances in vascular reconstruction devices and coil technologies have made embolization a popular effective strategy for treatment of relatively wide-neck cerebral aneurysms. However, protrusion occurs occasionally, little is known about the frequency, risk factors thrombo-embolic complications.We assessed frequency 330 unruptured aneurysm cases, examined occurrence infarction by diffusion-weighted magnetic resonance imaging (DW-MRI).Forty-four instances were encountered during (13.3%...

10.1177/1591019915582375 article EN Interventional Neuroradiology 2015-04-01

Abstract Calcium (Ca 2+ ) release from the endoplasmic reticulum (ER) controls numerous cellular functions including proliferation, and is regulated in part by inositol 1,4,5‐trisphosphate receptors (IP3Rs). IP3Rs are ubiquitously expressed intracellular Ca ‐release channels found many cell types. Although IP3R‐mediated has been implicated biochemical pathways that modulate during cycle progression not known. Sequence analysis of IP3R1 reveals presence two putative phosphorylation sites for...

10.1002/jcb.10720 article EN Journal of Cellular Biochemistry 2003-11-05

Mechanically-induced vasospasm often occurs during guiding catheter insertion, occasionally preventing advancement to the desired location. Delicate manipulation would be impossible without proper positioning of catheters, and vasospasm-induced cerebral hypoperfusion may cause thrombotic complications. From June 2012 December 2013, we prospectively analyzed 150 endovascular treatment cases, excluding acute for frequency vasospasm, risk factors, countermeasures. The associated factors such as...

10.2176/nmc.oa.2014-0268 article EN cc-by-nc-nd Neurologia medico-chirurgica 2015-01-01

Cerebral vasospasm is an unelucidated complication of subarachnoid hemorrhage. Various treatments exist against cerebral vasospasms however, consensus on the optimal treatment lacking. We use clazosentan, which used to prevent vasospasm, with multidrug combinations. In this study, we aimed clarify initial results using clazosentan in combinations real world. retrospectively investigated 54 patients who were treated for hemorrhage and received clazosentan. compared these basis two groups:...

10.1016/j.hest.2024.01.004 article EN cc-by-nc-nd Brain Hemorrhages 2024-01-26

10.1016/j.jstrokecerebrovasdis.2017.07.033 article EN Journal of Stroke and Cerebrovascular Diseases 2017-09-01

Objective and Importance: Non-traumatic subdural hemorrhage (SDH) caused by dural arteriovenous fistula (DAVF) is rare usually accompanied intracerebral (ICH) and/or subarachnoid (SAH). This report describes a very case of DAVF that non-traumatic acute SDH without ICH or SAH, which subsequently progressed into chronic SDH.

10.1055/s-0028-1085456 article EN min - Minimally Invasive Neurosurgery 2009-02-01

Reperfusion therapy, such as intravenous tissue-plasminogen activator (IV-tPA) and mechanical thrombectomy (MT) for acute ischemic stroke, may increase the incidence of symptomatic seizure (ASS) post-stroke epilepsy (PSE). This study aimed to analyze effect predictors reperfusion therapy ASS PSE limited large-vessel occlusions (LVOs).

10.5797/jnet.oa.2024-0007 article EN cc-by-nc Journal of Neuroendovascular Therapy 2024-01-01
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